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#mitochondrial — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #mitochondrial, aggregated by home.social.

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  1. Researchers identified the repurposed drug #Sildenafil as a highly promising and effective treatment capable of improving the disease course of Leigh Syndrome, a severe and previously untreatable #mitochondrial disorder affecting brain energy metabolism.
    #Neurology #CellBiology #MolecularBiology #Pharmaceutical #sflorg
    sflorg.com/2026/03/cbio0311260

  2. Researchers identified the repurposed drug #Sildenafil as a highly promising and effective treatment capable of improving the disease course of Leigh Syndrome, a severe and previously untreatable #mitochondrial disorder affecting brain energy metabolism.
    #Neurology #CellBiology #MolecularBiology #Pharmaceutical #sflorg
    sflorg.com/2026/03/cbio0311260

  3. Researchers identified the repurposed drug #Sildenafil as a highly promising and effective treatment capable of improving the disease course of Leigh Syndrome, a severe and previously untreatable #mitochondrial disorder affecting brain energy metabolism.
    #Neurology #CellBiology #MolecularBiology #Pharmaceutical #sflorg
    sflorg.com/2026/03/cbio0311260

  4. Researchers identified the repurposed drug #Sildenafil as a highly promising and effective treatment capable of improving the disease course of Leigh Syndrome, a severe and previously untreatable #mitochondrial disorder affecting brain energy metabolism.
    #Neurology #CellBiology #MolecularBiology #Pharmaceutical #sflorg
    sflorg.com/2026/03/cbio0311260

  5. Researchers identified the repurposed drug #Sildenafil as a highly promising and effective treatment capable of improving the disease course of Leigh Syndrome, a severe and previously untreatable #mitochondrial disorder affecting brain energy metabolism.
    #Neurology #CellBiology #MolecularBiology #Pharmaceutical #sflorg
    sflorg.com/2026/03/cbio0311260

  6. Researchers at Rice University and Baylor College of Medicine utilized a non-editing #CRISPR technique to safely increase #mitochondrial production in heart cells, improving cellular energy levels without causing cellular burnout or malfunction.
    #MolecularBiology #Bioengineering #Genetics #sflorg
    sflorg.com/2026/03/mbio0309260

  7. Researchers at Rice University and Baylor College of Medicine utilized a non-editing #CRISPR technique to safely increase #mitochondrial production in heart cells, improving cellular energy levels without causing cellular burnout or malfunction.
    #MolecularBiology #Bioengineering #Genetics #sflorg
    sflorg.com/2026/03/mbio0309260

  8. Researchers at Rice University and Baylor College of Medicine utilized a non-editing #CRISPR technique to safely increase #mitochondrial production in heart cells, improving cellular energy levels without causing cellular burnout or malfunction.
    #MolecularBiology #Bioengineering #Genetics #sflorg
    sflorg.com/2026/03/mbio0309260

  9. Researchers at Rice University and Baylor College of Medicine utilized a non-editing #CRISPR technique to safely increase #mitochondrial production in heart cells, improving cellular energy levels without causing cellular burnout or malfunction.
    #MolecularBiology #Bioengineering #Genetics #sflorg
    sflorg.com/2026/03/mbio0309260

  10. Researchers at Rice University and Baylor College of Medicine utilized a non-editing #CRISPR technique to safely increase #mitochondrial production in heart cells, improving cellular energy levels without causing cellular burnout or malfunction.
    #MolecularBiology #Bioengineering #Genetics #sflorg
    sflorg.com/2026/03/mbio0309260

  11. Paternal #mitochondrial inheritance is the transmission of mitochondrial DNA from a male parent to its offspring, a biological phenomenon recently proven to occur in plants far more frequently than the traditional paradigm of strict maternal inheritance dictates.
    #MolecularPlantPhysiology #Genetics #PlantBiology #Botany #sflorg
    sflorg.com/2026/03/bot03092601

  12. Paternal #mitochondrial inheritance is the transmission of mitochondrial DNA from a male parent to its offspring, a biological phenomenon recently proven to occur in plants far more frequently than the traditional paradigm of strict maternal inheritance dictates.
    #MolecularPlantPhysiology #Genetics #PlantBiology #Botany #sflorg
    sflorg.com/2026/03/bot03092601

  13. Paternal #mitochondrial inheritance is the transmission of mitochondrial DNA from a male parent to its offspring, a biological phenomenon recently proven to occur in plants far more frequently than the traditional paradigm of strict maternal inheritance dictates.
    #MolecularPlantPhysiology #Genetics #PlantBiology #Botany #sflorg
    sflorg.com/2026/03/bot03092601

  14. Paternal #mitochondrial inheritance is the transmission of mitochondrial DNA from a male parent to its offspring, a biological phenomenon recently proven to occur in plants far more frequently than the traditional paradigm of strict maternal inheritance dictates.
    #MolecularPlantPhysiology #Genetics #PlantBiology #Botany #sflorg
    sflorg.com/2026/03/bot03092601

  15. Paternal #mitochondrial inheritance is the transmission of mitochondrial DNA from a male parent to its offspring, a biological phenomenon recently proven to occur in plants far more frequently than the traditional paradigm of strict maternal inheritance dictates.
    #MolecularPlantPhysiology #Genetics #PlantBiology #Botany #sflorg
    sflorg.com/2026/03/bot03092601

  16. #Mitochondrial complex I (CI) assembly in plants is a complex, crucial process.
    Chen et al. provide insights into CI assembly pathways in #maize 🌽and discuss the critical role of ZmGLDH and CRK1 in CI assembly.

    doi.org/10.1111/jipb.13958

    @wileyplantsci
    #PlantScience #JIPB #RNA #botany

  17. #Mitochondrial complex I (CI) assembly in plants is a complex, crucial process.
    Chen et al. provide insights into CI assembly pathways in #maize 🌽and discuss the critical role of ZmGLDH and CRK1 in CI assembly.

    doi.org/10.1111/jipb.13958

    @wileyplantsci
    #PlantScience #JIPB #RNA #botany

  18. Interesting episode of the Naked Scientist #podcast about #mitochondrial diseases and new treatment options overcast.fm AAH2bj3HOto

    Overcast

  19. #Mitochondrial proteins are synthesized with presequences that target them to the #mitochondrion, but why are some more efficient than others? This study identifies presequences which recruit Hsp90 co-chaperones & TOMM34 to confer prioritized import efficiency @PLOSBiology plos.io/4m6spBN

  20. #Mitochondrial proteins are synthesized with presequences that target them to the #mitochondrion, but why are some more efficient than others? This study identifies presequences which recruit Hsp90 co-chaperones & TOMM34 to confer prioritized import efficiency @PLOSBiology plos.io/4m6spBN

  21. #Mitochondrial proteins are synthesized with presequences that target them to the #mitochondrion, but why are some more efficient than others? This study identifies presequences which recruit Hsp90 co-chaperones & TOMM34 to confer prioritized import efficiency @PLOSBiology plos.io/4m6spBN

  22. #Mitochondrial proteins are synthesized with presequences that target them to the #mitochondrion, but why are some more efficient than others? This study identifies presequences which recruit Hsp90 co-chaperones & TOMM34 to confer prioritized import efficiency @PLOSBiology plos.io/4m6spBN

  23. #Mitochondrial proteins are synthesized with presequences that target them to the #mitochondrion, but why are some more efficient than others? This study identifies presequences which recruit Hsp90 co-chaperones & TOMM34 to confer prioritized import efficiency @PLOSBiology plos.io/4m6spBN

  24. What is the therapeutic potential of correcting mutations by base editing of the #MitochondrialGenome? This study shows that #mitochondrial #BaseEditing can indeed functionally create & correct mitochondrial pathogenic #mutations in patient-derived cells @PLOSBiology plos.io/3ZMa2K2

  25. What is the therapeutic potential of correcting mutations by base editing of the #MitochondrialGenome? This study shows that #mitochondrial #BaseEditing can indeed functionally create & correct mitochondrial pathogenic #mutations in patient-derived cells @PLOSBiology plos.io/3ZMa2K2

  26. What is the therapeutic potential of correcting mutations by base editing of the #MitochondrialGenome? This study shows that #mitochondrial #BaseEditing can indeed functionally create & correct mitochondrial pathogenic #mutations in patient-derived cells @PLOSBiology plos.io/3ZMa2K2

  27. What is the therapeutic potential of correcting mutations by base editing of the #MitochondrialGenome? This study shows that #mitochondrial #BaseEditing can indeed functionally create & correct mitochondrial pathogenic #mutations in patient-derived cells @PLOSBiology plos.io/3ZMa2K2

  28. What is the therapeutic potential of correcting mutations by base editing of the #MitochondrialGenome? This study shows that #mitochondrial #BaseEditing can indeed functionally create & correct mitochondrial pathogenic #mutations in patient-derived cells @PLOSBiology plos.io/3ZMa2K2

  29. #Fungal infections are hard to treat due to #DrugResistance. @blake_billmyre &co use a high-throughput #TNseq system in #Cryptococcus neoformans to identify >1400 essential genes & reveal a role for #mitochondrial genes in #fluconazole sensitivity @PLOSBiology plos.io/4dz3iVm

  30. #Fungal infections are hard to treat due to #DrugResistance. @blake_billmyre &co use a high-throughput #TNseq system in #Cryptococcus neoformans to identify >1400 essential genes & reveal a role for #mitochondrial genes in #fluconazole sensitivity @PLOSBiology plos.io/4dz3iVm

  31. #Fungal infections are hard to treat due to #DrugResistance. @blake_billmyre &co use a high-throughput #TNseq system in #Cryptococcus neoformans to identify >1400 essential genes & reveal a role for #mitochondrial genes in #fluconazole sensitivity @PLOSBiology plos.io/4dz3iVm

  32. #Fungal infections are hard to treat due to #DrugResistance. @blake_billmyre &co use a high-throughput #TNseq system in #Cryptococcus neoformans to identify >1400 essential genes & reveal a role for #mitochondrial genes in #fluconazole sensitivity @PLOSBiology plos.io/4dz3iVm

  33. #Fungal infections are hard to treat due to #DrugResistance. @blake_billmyre &co use a high-throughput #TNseq system in #Cryptococcus neoformans to identify >1400 essential genes & reveal a role for #mitochondrial genes in #fluconazole sensitivity @PLOSBiology plos.io/4dz3iVm

  34. “Variation of the mitochondrial genome has been also studied as possible source of incomplete penetrance. In fact, constitutive variants defining mtDNA haplogroup J have been found to increase penetrance in families with the m.11778G>A and, more consistently, with the m.14484T>C mutations.” #dna #isogg #mtdna #mitochondrial #haplogroupj

    onlinelibrary.wiley.com/doi/ab

  35. “Variation of the mitochondrial genome has been also studied as possible source of incomplete penetrance. In fact, constitutive variants defining mtDNA haplogroup J have been found to increase penetrance in families with the m.11778G>A and, more consistently, with the m.14484T>C mutations.” #dna #isogg #mtdna #mitochondrial #haplogroupj

    onlinelibrary.wiley.com/doi/ab

  36. “Variation of the mitochondrial genome has been also studied as possible source of incomplete penetrance. In fact, constitutive variants defining mtDNA haplogroup J have been found to increase penetrance in families with the m.11778G>A and, more consistently, with the m.14484T>C mutations.” #dna #isogg #mtdna #mitochondrial #haplogroupj

    onlinelibrary.wiley.com/doi/ab

  37. “Variation of the mitochondrial genome has been also studied as possible source of incomplete penetrance. In fact, constitutive variants defining mtDNA haplogroup J have been found to increase penetrance in families with the m.11778G>A and, more consistently, with the m.14484T>C mutations.” #dna #isogg #mtdna #mitochondrial #haplogroupj

    onlinelibrary.wiley.com/doi/ab

  38. “These findings suggest that elevated Functional Impact (FI) score of mtDNA variants might contribute to premature aging in young adulthood.” #isogg #dna #epigenetics #mtDNA #mitochondrial #biologicalclock

    pmc.ncbi.nlm.nih.gov/articles/

  39. “These findings suggest that elevated Functional Impact (FI) score of mtDNA variants might contribute to premature aging in young adulthood.” #isogg #dna #epigenetics #mtDNA #mitochondrial #biologicalclock

    pmc.ncbi.nlm.nih.gov/articles/

  40. “These findings suggest that elevated Functional Impact (FI) score of mtDNA variants might contribute to premature aging in young adulthood.” #isogg #dna #epigenetics #mtDNA #mitochondrial #biologicalclock

    pmc.ncbi.nlm.nih.gov/articles/

  41. “These findings suggest that elevated Functional Impact (FI) score of mtDNA variants might contribute to premature aging in young adulthood.” #isogg #dna #epigenetics #mtDNA #mitochondrial #biologicalclock

    pmc.ncbi.nlm.nih.gov/articles/

  42. “We detailed the genetic, clinical, and molecular profiles of two Han Chinese families with MDD. These families exhibited a range of depression severities and notably low penetrance of MDD. Additionally, distinctive mtDNA polymorphisms associated with haplogroups H2 were identified.” #isogg #dna #mtDNA #mitochondrial #epigenetics #geneadons

    tandfonline.com/doi/full/10.21

  43. “We detailed the genetic, clinical, and molecular profiles of two Han Chinese families with MDD. These families exhibited a range of depression severities and notably low penetrance of MDD. Additionally, distinctive mtDNA polymorphisms associated with haplogroups H2 were identified.” #isogg #dna #mtDNA #mitochondrial #epigenetics #geneadons

    tandfonline.com/doi/full/10.21

  44. “We detailed the genetic, clinical, and molecular profiles of two Han Chinese families with MDD. These families exhibited a range of depression severities and notably low penetrance of MDD. Additionally, distinctive mtDNA polymorphisms associated with haplogroups H2 were identified.” #isogg #dna #mtDNA #mitochondrial #epigenetics #geneadons

    tandfonline.com/doi/full/10.21

  45. “We detailed the genetic, clinical, and molecular profiles of two Han Chinese families with MDD. These families exhibited a range of depression severities and notably low penetrance of MDD. Additionally, distinctive mtDNA polymorphisms associated with haplogroups H2 were identified.” #isogg #dna #mtDNA #mitochondrial #epigenetics #geneadons

    tandfonline.com/doi/full/10.21

  46. #Space Travel Damages #Astronauts At The Cellular Level
    #Mitochondrial damage is causing accelerated a#ging in astronauts and could hamper long-term space missions
    The report produced by the Guy Foundation, an independent British research foundation, cited multiple causes behind the cellular damage: #radiation and #zerogravity. While residents on the International Space Station exercise constantly to stave off muscle and bone loss, there’s no workout to help your cells.
    jalopnik.com/space-travel-is-d

  47. #Space Travel Damages #Astronauts At The Cellular Level
    #Mitochondrial damage is causing accelerated a#ging in astronauts and could hamper long-term space missions
    The report produced by the Guy Foundation, an independent British research foundation, cited multiple causes behind the cellular damage: #radiation and #zerogravity. While residents on the International Space Station exercise constantly to stave off muscle and bone loss, there’s no workout to help your cells.
    jalopnik.com/space-travel-is-d