home.social

#acutemyeloidleukemia — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #acutemyeloidleukemia, aggregated by home.social.

  1. #scRNAseq of 18,900 pre-leukemic & leukemic cells reveals transformation of #Hematopoietic #StemCells into full-blown #AcuteMyeloidLeukemia, emphasizing the critical role of #RNAsplicing in the emergence & maintenance of #leukemia #PLOSBiology plos.io/3LOnfer

  2. #scRNAseq of 18,900 pre-leukemic & leukemic cells reveals transformation of #Hematopoietic #StemCells into full-blown #AcuteMyeloidLeukemia, emphasizing the critical role of #RNAsplicing in the emergence & maintenance of #leukemia #PLOSBiology plos.io/3LOnfer

  3. #scRNAseq of 18,900 pre-leukemic & leukemic cells reveals transformation of #Hematopoietic #StemCells into full-blown #AcuteMyeloidLeukemia, emphasizing the critical role of #RNAsplicing in the emergence & maintenance of #leukemia #PLOSBiology plos.io/3LOnfer

  4. "Here, we utilized unbiased genetic screens to map drug/gene interactions for a variety of clinically approved therapies used in the treatment of AML. This effort highlighted a unique genetic relationship between response to venetoclax and the function of specific RNA splicing factors."

    #AML #leukemia #venetoclax #BCL2 #Apoptosis #RNASplicing #AcuteMyeloidLeukemia

    cell.com/cancer-cell/fulltext/

  5. Recent studies have shown that #AcuteMyeloidLeukemia favors #OxPhos metabolism. This #ASH22 abstract from my colleagues demonstrates with in vitro and in vivo models that the use of #ammocidin, an inhibitor of electron transport chain complex V, works synergistically with low-dose #venetoclax to kill #AML cells. Stop by poster 2652 or read more about it here: ashpublications.org/blood/arti #leukemia #cancer #oncology #hematology #hemonc #science #medicine