#hypercholesterolemia — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #hypercholesterolemia, aggregated by home.social.
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busybee: fluffy rambles: Medications are expensive https://beesbuzz.biz/blog/8443-Medications-are-expensive #Hypercholesterolemia #ClottingDisorder #Fibromyalgia #Medication #Blog #HRT
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"We show that Aster-B and Aster-C are critical for nonvesicular #cholesterol movement in enterocytes...Enterocytes lacking Asters accumulate PM cholesterol and show endoplasmic reticulum cholesterol depletion. Aster-deficient mice have impaired cholesterol absorption and are protected against diet-induced #hypercholesterolemia. Finally, the #Aster pathway can be targeted with a small-molecule inhibitor to manipulate cholesterol uptake."
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-Time for a short #Introduction-
I am a group leader in #MedicinalChemistry at the University of Parma. My lab combines #chemical & #computational techniques to develop novel pharmacological tools to study different Chronic Diseases (#CysticFibrosis, #IBD, #Hypercholesterolemia, #Alzheimer, #Cancer) and Infective Agents (#SARSCoV2, #Enterovirus, #Flavivirus, #Monkeypox, #HIV).
We are particularly interested in the development of #MultiTarget inhibitors and open to new #collaborations in #DrugDiscovery.
#Tooting (sooner or later) about the #chemistry and #science