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#flozin — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #flozin, aggregated by home.social.

  1. If a physician practice could get somehow get their Medicare patients on #angiotensin blockade #flozin #nsMRA and #glp1 (e.g. secondary insurance or coinsurance) why would they partner with a #VBC and share cost savings from the drugs? Just write a script & use the ...

  2. electronic health record and appointment reminders to track and assist with adherence. Just two of the now generic #4pillars (angiotensin and #flozin) pack more punch than what the #VBC ever promised to deliver. In the angiotensin blocker, intolerant patients ...

  3. If a physician practice could get somehow get their Medicare patients on #angiotensin blockade #flozin #nsMRA and #glp1 (e.g. secondary insurance or coinsurance) why would they partner with a #VBC and share cost savings from the drugs? Just write a script & use the ...

  4. electronic health record and appointment reminders to track and assist with adherence. Just two of the now generic #4pillars (angiotensin and #flozin) pack more punch than what the #VBC ever promised to deliver. In the angiotensin blocker, intolerant patients ...

  5. This "living" guideline document will unlive many people with diabetes if applied.

    Why are guideline ppl addicted to sulfunylureas/nsulin/metformin ?

    Those are useful to lower A1c from stratospheric levels, but if we are thinking hard outcomes improvement, the answer is #flozin & #glp1

    #fail

  6. This "living" guideline document will unlive many people with diabetes if applied.

    Why are guideline ppl addicted to sulfunylureas/nsulin/metformin ?

    Those are useful to lower A1c from stratospheric levels, but if we are thinking hard outcomes improvement, the answer is #flozin & #glp1

    #fail

  7. This "living" guideline document will unlive many people with diabetes if applied.

    Why are guideline ppl addicted to sulfunylureas/nsulin/metformin ?

    Those are useful to lower A1c from stratospheric levels, but if we are thinking hard outcomes improvement, the answer is #flozin & #glp1

    #fail

  8. This "living" guideline document will unlive many people with diabetes if applied.

    Why are guideline ppl addicted to sulfunylureas/nsulin/metformin ?

    Those are useful to lower A1c from stratospheric levels, but if we are thinking hard outcomes improvement, the answer is #flozin & #glp1

    #fail

  9. This "living" guideline document will unlive many people with diabetes if applied.

    Why are guideline ppl addicted to sulfunylureas/nsulin/metformin ?

    Those are useful to lower A1c from stratospheric levels, but if we are thinking hard outcomes improvement, the answer is #flozin & #glp1

    #fail

  10. This "living" guideline document will unlive many people with diabetes if applied. Why are guideline ppl addicted to sulfunylureas/nsulin/metformin ? Those are useful to lower A1c from stratospheric levels, but if we are thinking hard outcomes improvement, the answer is #flozin & #glp1 #fail

  11. This "living" guideline document will unlive many people with diabetes if applied. Why are guideline ppl addicted to sulfunylureas/nsulin/metformin ? Those are useful to lower A1c from stratospheric levels, but if we are thinking hard outcomes improvement, the answer is #flozin & #glp1 #fail

  12. The results of #confidence were the best news today: combined treatment with #flozin #sglt2i and non steroidal #MRA cut by more than half the level of kidney damage markers (urine albumin/creatinine ratio). In every single trial to date cutting UACR has led to kidney protection

  13. The results of #confidence were the best news today: combined treatment with #flozin #sglt2i and non steroidal #MRA cut by more than half the level of kidney damage markers (urine albumin/creatinine ratio). In every single trial to date cutting UACR has led to kidney protection

  14. The results of #confidence were the best news today: combined treatment with #flozin #sglt2i and non steroidal #MRA cut by more than half the level of kidney damage markers (urine albumin/creatinine ratio). In every single trial to date cutting UACR has led to kidney protection

  15. The results of #confidence were the best news today: combined treatment with #flozin #sglt2i and non steroidal #MRA cut by more than half the level of kidney damage markers (urine albumin/creatinine ratio). In every single trial to date cutting UACR has led to kidney protection

  16. The results of #confidence were the best news today: combined treatment with #flozin #sglt2i and non steroidal #MRA cut by more than half the level of kidney damage markers (urine albumin/creatinine ratio). In every single trial to date cutting UACR has led to kidney protection

  17. The results of #confidence were the best news today: combined treatment with #flozin #sglt2i and non steroidal #MRA cut by more than half the level of kidney damage markers (urine albumin/creatinine ratio). In every single trial to date cutting UACR has led to kidney protection

  18. The results of #confidence were the best news today: combined treatment with #flozin #sglt2i and non steroidal #MRA cut by more than half the level of kidney damage markers (urine albumin/creatinine ratio). In every single trial to date cutting UACR has led to kidney protection

  19. Any veterinarians using bexagliflozin (Bexacat) off label for non diabetic kidney disease in cats? #flozin #ckd

  20. Any veterinarians using bexagliflozin (Bexacat) off label for non diabetic kidney disease in cats? #flozin #ckd

  21. Any veterinarians using bexagliflozin (Bexacat) off label for non diabetic kidney disease in cats? #flozin #ckd

  22. Any veterinarians using bexagliflozin (Bexacat) off label for non diabetic kidney disease in cats? #flozin #ckd

  23. Any veterinarians using bexagliflozin (Bexacat) off label for non diabetic kidney disease in cats? #flozin #ckd

  24. Any veterinarians using bexagliflozin (Bexacat) off label for non diabetic kidney disease in cats? #flozin #ckd

  25. The nice thing about knowing #rstats, is that one can often answer some clinical questions using public data. E.g. do I expect a benefit when combining #flozin and #Glp1RA in patients living with diabetes and kidney disease? Let's use 👇from www.sciencedirect.com/science/arti... to answer the Q 1/

  26. HR = exp(-0.38-0.19) ~ 0.57 (43% reduction in bad kidney juju) which is very close to the estimate of 0.54 given by @brendonneuen.bsky.social by extrapolating the effect sizes of the trials available at that time. Conclusions: 1. #rstats can answer clinical questions 2. Use #GLP1RA + #flozin /

  27. The nice thing about knowing #rstats, is that one can often answer some clinical questions using public data. E.g. do I expect a benefit when combining #flozin and #Glp1RA in patients living with diabetes and kidney disease? Let's use 👇from www.sciencedirect.com/science/arti... to answer the Q 1/

  28. We are fully in Bayesian territory for such secondary analyses, so let's try to fit models for events (logistic) and event rates (poisson) in #rstats Both logistic and Poisson show that SGLT2i #flozin and #GLP1RA are associated with improvement in kidney outcomes. 2/

  29. The nice thing about knowing #rstats, is that one can often answer some clinical questions using public data. E.g. do I expect a benefit when combining #flozin and #Glp1RA in patients living with diabetes and kidney disease? Let's use 👇from www.sciencedirect.com/science/arti... to answer the Q 1/

  30. The nice thing about knowing #rstats, is that one can often answer some clinical questions using public data. E.g. do I expect a benefit when combining #flozin and #Glp1RA in patients living with diabetes and kidney disease? Let's use 👇from www.sciencedirect.com/science/arti... to answer the Q 1/

  31. The nice thing about knowing #rstats, is that one can often answer some clinical questions using public data. E.g. do I expect a benefit when combining #flozin and #Glp1RA in patients living with diabetes and kidney disease? Let's use 👇from www.sciencedirect.com/science/arti... to answer the Q 1/

  32. Slidedeck from an internal presentation on diabetic kidney disease 👇 Nephrologist's take on the effect and impact of SGLT-2 inhibitors, GLP-1 RAs and ns-MRA on #Kidney Disease in people with #diabetes #flozin #sglt2i #MRA #GLP1RA #MedEd #MedSky #NephSky www.slideshare.net/slideshow/ne...

  33. The take home point for clinicians: don't stop the drugs thinking you will get much or a sustained legacy/carryover effect: #sglt2i #flozin drugs have a fast on and a fast off.

    x.com

  34. The take home point from the long term extension of the #sglt2i #flozin EMPA-KIDNEY trial is that the benefit washes VERY SOON after one stops the drug. www.nejm.org/doi/full/10.... A non-proportional hazards #stats analysis would have shown it directly, but it is also evident in the text

    Long-Term Effects of Empaglifl...

  35. social media discussions are a richer source of information for #Nephrology #Flozin edition than most other

    kireports.org/article/S2468-02

    yes, there's a selection bias in who responded to the survey

    h/t @kdjhaveri

  36. social media discussions are a richer source of information for #Nephrology #Flozin edition than most other

    kireports.org/article/S2468-02

    yes, there's a selection bias in who responded to the survey

    h/t @kdjhaveri

  37. social media discussions are a richer source of information for #Nephrology #Flozin edition than most other

    kireports.org/article/S2468-02

    yes, there's a selection bias in who responded to the survey

    h/t @kdjhaveri

  38. social media discussions are a richer source of information for #Nephrology #Flozin edition than most other

    kireports.org/article/S2468-02

    yes, there's a selection bias in who responded to the survey

    h/t @kdjhaveri

  39. social media discussions are a richer source of information for #Nephrology #Flozin edition than most other

    kireports.org/article/S2468-02

    yes, there's a selection bias in who responded to the survey

    h/t @kdjhaveri

  40. Endothelin blockade works (eg PRECISION, and PROTECT) but does cause sodium retention. What’s the best way to proactively prevent this? In the RCTs they exclude patients with HF or high BNP, and still see weight gain. Should they be combined with a natriuretic, as @ChristosArgyrop and others have suggested?

    In this small 🐀 study, adding a #Flozin to #Zibotentan did just that. Makes a lot of sense. Two good meds being synergistic. Let’s do a human trial now!

    academic.oup.com/ndt/advance-a

  41. Endothelin blockade works (eg PRECISION, and PROTECT) but does cause sodium retention. What’s the best way to proactively prevent this? In the RCTs they exclude patients with HF or high BNP, and still see weight gain. Should they be combined with a natriuretic, as @ChristosArgyrop and others have suggested?

    In this small 🐀 study, adding a #Flozin to #Zibotentan did just that. Makes a lot of sense. Two good meds being synergistic. Let’s do a human trial now!

    academic.oup.com/ndt/advance-a

  42. Endothelin blockade works (eg PRECISION, and PROTECT) but does cause sodium retention. What’s the best way to proactively prevent this? In the RCTs they exclude patients with HF or high BNP, and still see weight gain. Should they be combined with a natriuretic, as @ChristosArgyrop and others have suggested?

    In this small 🐀 study, adding a #Flozin to #Zibotentan did just that. Makes a lot of sense. Two good meds being synergistic. Let’s do a human trial now!

    academic.oup.com/ndt/advance-a

  43. Endothelin blockade works (eg PRECISION, and PROTECT) but does cause sodium retention. What’s the best way to proactively prevent this? In the RCTs they exclude patients with HF or high BNP, and still see weight gain. Should they be combined with a natriuretic, as @ChristosArgyrop and others have suggested?

    In this small 🐀 study, adding a #Flozin to #Zibotentan did just that. Makes a lot of sense. Two good meds being synergistic. Let’s do a human trial now!

    academic.oup.com/ndt/advance-a

  44. Endothelin blockade works (eg PRECISION, and PROTECT) but does cause sodium retention. What’s the best way to proactively prevent this? In the RCTs they exclude patients with HF or high BNP, and still see weight gain. Should they be combined with a natriuretic, as @ChristosArgyrop and others have suggested?

    In this small 🐀 study, adding a #Flozin to #Zibotentan did just that. Makes a lot of sense. Two good meds being synergistic. Let’s do a human trial now!

    academic.oup.com/ndt/advance-a