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#glp1ra — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #glp1ra, aggregated by home.social.

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  1. Comprehensive update on diabetic kidney disease, cardiokidney metabolic syndrome, screening, diagnosis, and modern pharmacological treatments including SGLT2 inhibitors and MRAs for improved cardiorenal outcomes. #dkd #CKD #SGLT2i #GLP1RA

    slideshare.net/slideshow/manag

  2. Comprehensive update on diabetic kidney disease, cardiokidney metabolic syndrome, screening, diagnosis, and modern pharmacological treatments including SGLT2 inhibitors and MRAs for improved cardiorenal outcomes. #dkd #CKD #SGLT2i #GLP1RA

    slideshare.net/slideshow/manag

  3. Comprehensive update on diabetic kidney disease, cardiokidney metabolic syndrome, screening, diagnosis, and modern pharmacological treatments including SGLT2 inhibitors and MRAs for improved cardiorenal outcomes. #dkd #CKD #SGLT2i #GLP1RA www.slideshare.net/slideshow/ma...

    Managing Diabetic Kidney Disea...

  4. I expect the #glp1ra online and in-real-life shaming and bullying to get worse after the publication of #SURPASS-CVOT #tirzepatide #dulaglutide.
    I think my #gigablock game will surpass (pun intended) my peak of the early pandemic era esp after I have gone through the egfr data.

  5. I expect the #glp1ra online and in-real-life shaming and bullying to get worse after the publication of #SURPASS-CVOT #tirzepatide #dulaglutide.
    I think my #gigablock game will surpass (pun intended) my peak of the early pandemic era esp after I have gone through the egfr data.

  6. I expect the #glp1ra online and in-real-life shaming and bullying to get worse after the publication of #SURPASS-CVOT #tirzepatide #dulaglutide. I think my #gigablock game will surpass (pun intended) my peak of the early pandemic era esp after I have gone through the egfr data.

  7. @AusSMC
    Yes! And (clear fluids excepted) consider a 24h fast before general anaesthesia. Nobody likes aspiration pneumonia.

    #medicine #GLP1A #GLP1RA #anesthesia

  8. @AusSMC
    Yes! And (clear fluids excepted) consider a 24h fast before general anaesthesia. Nobody likes aspiration pneumonia.

    #medicine #GLP1A #GLP1RA #anesthesia

  9. 1000% this .... the need for personalization of #glp1ra dose has been rather obvious (and, in fact, was the part of the rationale) behind AWARD-11

  10. 1000% this .... the need for personalization of #glp1ra dose has been rather obvious (and, in fact, was the part of the rationale) behind AWARD-11

  11. 1000% this .... the need for personalization of #glp1ra dose has been rather obvious (and, in fact, was the part of the rationale) behind AWARD-11

  12. The Dark Side of Weight Loss: GLP-1 RAs Linked to Increased Psychiatric Risks

    A groundbreaking study reveals a startling correlation between glucagon-like peptide-1 receptor agonist (GLP-1 RA) medications and heightened risks of depression, anxiety, and suicidal behavior in pat...

    news.lavx.hu/article/the-dark-

    #news #tech #GLP1RA #MentalHealth #ObesityTreatment

  13. HR = exp(-0.38-0.19) ~ 0.57 (43% reduction in bad kidney juju) which is very close to the estimate of 0.54 given by @brendonneuen.bsky.social by extrapolating the effect sizes of the trials available at that time. Conclusions: 1. #rstats can answer clinical questions 2. Use #GLP1RA + #flozin /

  14. The nice thing about knowing #rstats, is that one can often answer some clinical questions using public data. E.g. do I expect a benefit when combining #flozin and #Glp1RA in patients living with diabetes and kidney disease? Let's use 👇from www.sciencedirect.com/science/arti... to answer the Q 1/

  15. We are fully in Bayesian territory for such secondary analyses, so let's try to fit models for events (logistic) and event rates (poisson) in #rstats Both logistic and Poisson show that SGLT2i #flozin and #GLP1RA are associated with improvement in kidney outcomes. 2/

  16. The evidence is strong for #SGLT2i and moderate for #GLP1RA (but note that the source data was only designed to infer the effects of the SGLT2i, not the GLP1RA in diabetic kidney disease). Note that combining the 2 drugs has an estimated benefit of .... 3/

  17. Slidedeck from an internal presentation on diabetic kidney disease 👇 Nephrologist's take on the effect and impact of SGLT-2 inhibitors, GLP-1 RAs and ns-MRA on #Kidney Disease in people with #diabetes #flozin #sglt2i #MRA #GLP1RA #MedEd #MedSky #NephSky www.slideshare.net/slideshow/ne...

  18. Sorry, #dulaglutide med #trulicity; the more general description of these drugs is #glp1 receptor agonists.

    medscape.com/viewarticle/glp-1

    Apparently various professional orgs have been kinda all over the map on whether or not to hold such meds pre-op, but now they are coalescing -- still without formal evidence-based guidance, mind you -- around 24-hour liquid diet in preoperative phase, especially for higher doses of the meds for patients on weekly regimens.

    #glp #glp1ra #trulicity #mounjaro #healthcare

  19. Sorry, #dulaglutide med #trulicity; the more general description of these drugs is #glp1 receptor agonists.

    medscape.com/viewarticle/glp-1

    Apparently various professional orgs have been kinda all over the map on whether or not to hold such meds pre-op, but now they are coalescing -- still without formal evidence-based guidance, mind you -- around 24-hour liquid diet in preoperative phase, especially for higher doses of the meds for patients on weekly regimens.

    #glp #glp1ra #trulicity #mounjaro #healthcare

  20. Today is Mounjaro day. Not only that, I get to bump up my dose. Hopefully by the end of the year I’ll be back to the maximum dose. We shall see how supply works out.

    #Diabetes #Mounjaro #GLP1RA

  21. I really wish content creators, especially large ones, that do news and news commentary, would stop referring to GLP-1 drugs as weight loss drugs. This erases the problem that diabetics face with access to this drug through these major shortages.

    This has been a diabetes drug for far longer than it was available for weight loss. And it’s only a second gen weight loss version of it that got popular.

    #Diabetes #GLP1RA #Ozempic #Mounjaro

  22. Looks like a processing error. Wonder if they tried to do it on Friday during the IT shitstorm.

    They had already ordered it so it was on hand when they retried and it went through.

    #Diabetes #GLP1RA #Mounjaro

  23. Well, CVS got a coverage rejection, but the Cigna app says it’s covered. Cigna seems to do mid-year formulary changes (has happened in the past) so who knows.

    #Diabetes #GLP1RA #Mounjaro

  24. Mounjaro is no longer covered by my insurance.

    Best healthcare in the world. /s

    (I don’t use it for weight loss)

    #Diabetes #GLP1RA #Mounjaro

  25. Mounjaro is no longer covered by my insurance.

    Best healthcare in the world. /s

    (I don’t use it for weight loss)

    #Diabetes #GLP1RA #Mounjaro

  26. So far, I'm having no negative side effects from restarting Mounjaro.

    I'm also not experiencing the appetite suppression.

    However, it seems my dawn/fotf is recovering on its own this morning without using insulin. So might be getting the benefits already.

    Will have to monitor.

    #Diabetes #Mounjaro #GLP1RA

  27. I was in a hurry to pick up my prescriptions. Tomorrow I will be going back to ask for an explanation how this is a 90 day supply of insulin.

    On the bright side, I did also get Mounjaro 5mg. So there’s that. I think I’m going to wait on restarting it so I can build up some buffer supply.

    #Diabetes #Mounjaro #GLP1RA #Insulin #Lyumjev

  28. Last night, while relaxing for the evening before bed, I was coasting around 110mg/dL BG. Which is super good for a diabetic. I went to bed. Benson woke me up because he needed to go potty and other attention (super rare for him to wake me up). I look at my watch and my CGM is reporting 180mg/dL. I pull up my app and it had spiked.

    I’m supposed to still have a semi-functional pancreas as a far progressed T2D. So I decided not to correct it.

    I floated around 170mg/dL all night and woke up to 190mg/dL and climbing.

    My next doctor’s visit is in July, where I will request a c-peptide test to see what the effect on endogenous insulin has been while losing access to Mounjaro. I don’t think my diagnosis should change from T2D, but as time goes on I suspect my c-peptide result might look like an early T1D diagnosis, which is a potential progression of T2D.

    Finally took that correction this morning.

    Fun times with diabetes.

    #Diabetes #T2D #BloodGlucose #Insulin #Mounjaro #GLP1RA #Frustration

  29. With my GLP-1 drugs basically completely out of my system, my insulin sensitivity is a bit shot. My insulin use has gone up a little bit due to my ratios changing. But with my low carb diet with intermittent fasting, it didn’t go up a lot.

    Need to update the doc with this info.

    Still no signs of when the Mounjaro shortage will let up.

    #Diabetes #T2D #GLP1RA #Insulin #Mounjaro #Shortage

  30. I did an experiment in my nutritional regimen for a few months, which resulted in weight gain instead of loss.

    I’ve reverted that change and went back to my old regimen. In less than a month I’ve already dropped the gained weight back off.

    And this is in spite of losing access to my GLP-1 medication and starting MDI.

    Now to lose even more weight!

    #WeightLoss #Diet #GLP1RA #Mounjaro #Insulin #Diabetes #T2D #Nutrition

  31. My doc insists on keeping some form of GLP-1 drug going, even if it’s not the one known to work best, and if she can only get me on a low dose despite being on max dose.

    And is being cagey about getting me going with MDI even if that will result in more reliable access to treatment.

    I’ve requested to keep the existing prescription, and push for the MDI option in the meantime.

    #Diabetes #T2D #Insulin #GLP1RA #Shortage #Mounjaro

  32. Mounjaro and Ozempic appear to no longer be available for ordering, apparently. At least for the doses I use. I now have an order in for Trulicity 3mg. I've been able to order the others in the past, only to watch them get cancelled, so this doesn't mean I'll get it.

    Again, I use this for diabetes management, not weight loss. I haven't seen weight loss benefits from it in many years.

    #Diabetes #T2D #GLP1RA #Mounjaro #Ozempic #Trulicity #Shortage

  33. So I can’t get Ozempic. I’m a week off of this drug class. My doc just essentially told me to ask the pharmacy what they can get so we can know our options. Just so we can get _something_. This is where we are.

    #Diabetes #T2D #GLP1RA

  34. @hswapnil @mike_johansen This is cool! We are working on medication specific guidelines to harmonize prescriptions of #Flozins, #GLP1ra, #nsMRA etc across #primarycare, #cardiology, #endocrinology and #nephrology, which has been a fun project. I think at our institution, nephrology prescribed most aggressively, but that is probably the effect of having Amy Mottl in our division.