#foxp3 — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #foxp3, aggregated by home.social.
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1/ An elegant study from the Sakaguchi and Hori labs explores the role of Foxp3 in Tregs. Despite extensive work, many aspects of Treg biology remain unresolved. this work uncovers another piece of the puzzle.
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1/ An elegant study from the Sakaguchi and Hori labs explores the role of Foxp3 in Tregs. Despite extensive work, many aspects of Treg biology remain unresolved. this work uncovers another piece of the puzzle.
⬇️
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1/ An elegant study from the Sakaguchi and Hori labs explores the role of Foxp3 in Tregs. Despite extensive work, many aspects of Treg biology remain unresolved. this work uncovers another piece of the puzzle.
⬇️
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1/ An elegant study from the Sakaguchi and Hori labs explores the role of Foxp3 in Tregs. Despite extensive work, many aspects of Treg biology remain unresolved. this work uncovers another piece of the puzzle.
⬇️
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1/ An elegant study from the Sakaguchi and Hori labs explores the role of Foxp3 in Tregs. Despite extensive work, many aspects of Treg biology remain unresolved. this work uncovers another piece of the puzzle.
⬇️
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This level of scientific ignorance is unacceptable. You cannot draw conclusions about antigen-specific Treg inhibition from in vitro assays when they do not align with in vivo suppression readouts.
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This level of scientific ignorance is unacceptable. You cannot draw conclusions about antigen-specific Treg inhibition from in vitro assays when they do not align with in vivo suppression readouts.
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This level of scientific ignorance is unacceptable. You cannot draw conclusions about antigen-specific Treg inhibition from in vitro assays when they do not align with in vivo suppression readouts.
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This level of scientific ignorance is unacceptable. You cannot draw conclusions about antigen-specific Treg inhibition from in vitro assays when they do not align with in vivo suppression readouts.
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This level of scientific ignorance is unacceptable. You cannot draw conclusions about antigen-specific Treg inhibition from in vitro assays when they do not align with in vivo suppression readouts.
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Why do studies claiming #Treg induction by novel designer drugs test them only when given before or with antigen, rather than in established disease that more closely reflects human cases?
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Why do studies claiming #Treg induction by novel designer drugs test them only when given before or with antigen, rather than in established disease that more closely reflects human cases?
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Why do studies claiming #Treg induction by novel designer drugs test them only when given before or with antigen, rather than in established disease that more closely reflects human cases?
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Why do studies claiming #Treg induction by novel designer drugs test them only when given before or with antigen, rather than in established disease that more closely reflects human cases?
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Why do studies claiming #Treg induction by novel designer drugs test them only when given before or with antigen, rather than in established disease that more closely reflects human cases?
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The exclusive role of RORγt⁺ APCs in inducing or expanding Tregs in the periphery has been challenged. Back to square one.
https://www.biorxiv.org/content/10.64898/2026.02.26.707908v1
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The exclusive role of RORγt⁺ APCs in inducing or expanding Tregs in the periphery has been challenged. Back to square one.
https://www.biorxiv.org/content/10.64898/2026.02.26.707908v1
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The exclusive role of RORγt⁺ APCs in inducing or expanding Tregs in the periphery has been challenged. Back to square one.
https://www.biorxiv.org/content/10.64898/2026.02.26.707908v1
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The exclusive role of RORγt⁺ APCs in inducing or expanding Tregs in the periphery has been challenged. Back to square one.
https://www.biorxiv.org/content/10.64898/2026.02.26.707908v1
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The exclusive role of RORγt⁺ APCs in inducing or expanding Tregs in the periphery has been challenged. Back to square one.
https://www.biorxiv.org/content/10.64898/2026.02.26.707908v1
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【關鍵專訪】2025諾貝爾醫學獎：「調節性T細胞」像憲兵？相關研究為何曾被認為是「假的」？
julia 2025-10-07 14:13:00 CST
2025諾貝爾醫學獎昨（6）日揭曉，由美國學者布朗柯、藍斯德爾以及日本免疫學家坂口志文共享殊榮。究竟研究的內容是什麼？為何學者以「軍隊中的憲兵」來進行比喻？《關鍵評論網》邀請學者就這次獲獎的研究內容進行白話解說。
https://www.thenewslens.com/article/259513
#坂口志文 #日本 #負向調控 #免疫抑制 #自體免疫疾病 #調節性T細胞 #Foxp3 #布朗柯 #科學 #諾貝爾醫學獎 #諾貝爾獎 #免疫系統 #器官移植 #陳念榮 #藍斯德爾 -
13. In summary: tolerance to self is a fixed, static system established at birth. It does not change dynamically during an individual’s life.
#immunology
#tolerance
#selfnonself
#science
#theory
#Foxp3
#Tregs -
13. In summary: tolerance to self is a fixed, static system established at birth. It does not change dynamically during an individual’s life.
#immunology
#tolerance
#selfnonself
#science
#theory
#Foxp3
#Tregs -
13. In summary: tolerance to self is a fixed, static system established at birth. It does not change dynamically during an individual’s life.
#immunology
#tolerance
#selfnonself
#science
#theory
#Foxp3
#Tregs -
13. In summary: tolerance to self is a fixed, static system established at birth. It does not change dynamically during an individual’s life.
#immunology
#tolerance
#selfnonself
#science
#theory
#Foxp3
#Tregs -
13. In summary: tolerance to self is a fixed, static system established at birth. It does not change dynamically during an individual’s life.
#immunology
#tolerance
#selfnonself
#science
#theory
#Foxp3
#Tregs -
Another study using auxin-inducible #Foxp3 degradation just after Rudensky lab’s preprint. Curious overlap. Parallel thinking or a race to publish? 🧬👀
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Another study using auxin-inducible #Foxp3 degradation just after Rudensky lab’s preprint. Curious overlap. Parallel thinking or a race to publish? 🧬👀
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Another study using auxin-inducible #Foxp3 degradation just after Rudensky lab’s preprint. Curious overlap. Parallel thinking or a race to publish? 🧬👀
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Another study using auxin-inducible #Foxp3 degradation just after Rudensky lab’s preprint. Curious overlap. Parallel thinking or a race to publish? 🧬👀
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Another study using auxin-inducible #Foxp3 degradation just after Rudensky lab’s preprint. Curious overlap. Parallel thinking or a race to publish? 🧬👀
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1/ 🧪 The Rudensky lab never shies away from using cutting-edge gene tech to study Tregs. Their latest approach? Reversible protein degradation via ubiquitination. 👀 #Immunology #Tregs #science #Foxp3
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1/ 🧪 The Rudensky lab never shies away from using cutting-edge gene tech to study Tregs. Their latest approach? Reversible protein degradation via ubiquitination. 👀 #Immunology #Tregs #science #Foxp3
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1/ 🧪 The Rudensky lab never shies away from using cutting-edge gene tech to study Tregs. Their latest approach? Reversible protein degradation via ubiquitination. 👀 #Immunology #Tregs #science #Foxp3
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1/ 🧪 The Rudensky lab never shies away from using cutting-edge gene tech to study Tregs. Their latest approach? Reversible protein degradation via ubiquitination. 👀 #Immunology #Tregs #science #Foxp3
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1/ 🧪 The Rudensky lab never shies away from using cutting-edge gene tech to study Tregs. Their latest approach? Reversible protein degradation via ubiquitination. 👀 #Immunology #Tregs #science #Foxp3
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2/💡 They engineered a system to reversibly degrade Foxp3, the master regulator of Treg identity. This lets them test what happens when #Foxp3 protein vanishes in adult mice. 🔄🧬
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2/💡 They engineered a system to reversibly degrade Foxp3, the master regulator of Treg identity. This lets them test what happens when #Foxp3 protein vanishes in adult mice. 🔄🧬
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2/💡 They engineered a system to reversibly degrade Foxp3, the master regulator of Treg identity. This lets them test what happens when #Foxp3 protein vanishes in adult mice. 🔄🧬
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2/💡 They engineered a system to reversibly degrade Foxp3, the master regulator of Treg identity. This lets them test what happens when #Foxp3 protein vanishes in adult mice. 🔄🧬
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2/💡 They engineered a system to reversibly degrade Foxp3, the master regulator of Treg identity. This lets them test what happens when #Foxp3 protein vanishes in adult mice. 🔄🧬
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6/ 🔬 These inconsistencies raise key questions about how Treg suppression works in different contexts. More research needed! 🏗️📖
What do you think? Drop your thoughts below! ⬇️💬
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6/ 🔬 These inconsistencies raise key questions about how Treg suppression works in different contexts. More research needed! 🏗️📖
What do you think? Drop your thoughts below! ⬇️💬
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6/ 🔬 These inconsistencies raise key questions about how Treg suppression works in different contexts. More research needed! 🏗️📖
What do you think? Drop your thoughts below! ⬇️💬
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6/ 🔬 These inconsistencies raise key questions about how Treg suppression works in different contexts. More research needed! 🏗️📖
What do you think? Drop your thoughts below! ⬇️💬
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6/ 🔬 These inconsistencies raise key questions about how Treg suppression works in different contexts. More research needed! 🏗️📖
What do you think? Drop your thoughts below! ⬇️💬
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1/ 📢 A new study was recently published in Science Translational Medicine investigating antigen specificity in Treg-mediated suppression of effector T cells in a celiac model. 🔬🍞
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1/ 📢 A new study was recently published in Science Translational Medicine investigating antigen specificity in Treg-mediated suppression of effector T cells in a celiac model. 🔬🍞
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1/ 📢 A new study was recently published in Science Translational Medicine investigating antigen specificity in Treg-mediated suppression of effector T cells in a celiac model. 🔬🍞