#ecdna — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #ecdna, aggregated by home.social.
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Thrilled to see our work featured on the cover of Molecular Cell.
The image: an electron micrograph of an i-loop, the DNA structure we propose as a source of eccDNA formation. Almost like catching circular DNA formation in the act.
#MolecularCell #eccDNA #ecDNA #CancerResearch #GenomeInstability #DNARepair @MolecularCell
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Thrilled to see our work featured on the cover of Molecular Cell.
The image: an electron micrograph of an i-loop, the DNA structure we propose as a source of eccDNA formation. Almost like catching circular DNA formation in the act.
#MolecularCell #eccDNA #ecDNA #CancerResearch #GenomeInstability #DNARepair @MolecularCell
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Thrilled to see our work featured on the cover of Molecular Cell.
The image: an electron micrograph of an i-loop, the DNA structure we propose as a source of eccDNA formation. Almost like catching circular DNA formation in the act.
#MolecularCell #eccDNA #ecDNA #CancerResearch #GenomeInstability #DNARepair @MolecularCell
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Thrilled to see our work featured on the cover of Molecular Cell.
The image: an electron micrograph of an i-loop, the DNA structure we propose as a source of eccDNA formation. Almost like catching circular DNA formation in the act.
#MolecularCell #eccDNA #ecDNA #CancerResearch #GenomeInstability #DNARepair @MolecularCell
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Thrilled to see our work featured on the cover of Molecular Cell.
The image: an electron micrograph of an i-loop, the DNA structure we propose as a source of eccDNA formation. Almost like catching circular DNA formation in the act.
#MolecularCell #eccDNA #ecDNA #CancerResearch #GenomeInstability #DNARepair @MolecularCell
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Huge congratulations to @EZ_eta for leading the experimental work, and a big thank you to our collaborators at IIT for their Nanopore expertise, as well as to Michele Giannattasio head of the EM on Single Molecules Facility for his contribution to the structural analysis.
#eccDNA #ecDNA #CancerResearch #GenomeInstability #DNARepair #ReplicationStress
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Huge congratulations to @EZ_eta for leading the experimental work, and a big thank you to our collaborators at IIT for their Nanopore expertise, as well as to Michele Giannattasio head of the EM on Single Molecules Facility for his contribution to the structural analysis.
#eccDNA #ecDNA #CancerResearch #GenomeInstability #DNARepair #ReplicationStress
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Huge congratulations to @EZ_eta for leading the experimental work, and a big thank you to our collaborators at IIT for their Nanopore expertise, as well as to Michele Giannattasio head of the EM on Single Molecules Facility for his contribution to the structural analysis.
#eccDNA #ecDNA #CancerResearch #GenomeInstability #DNARepair #ReplicationStress
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How do cancer-associated extrachromosomal circular DNAs arise?
In our new manuscript, we show that single-strand DNA damage in repetitive sequences can trigger i-loop formation and eccDNA generation. What started at telomeres may reflect a much broader principle across the genome and help explain how ecDNA may emerge in cancer.
https://authors.elsevier.com/a/1n0wG3vVUPZO38#eccDNA #ecDNA #CancerResearch #GenomeInstability #DNARepair #ReplicationStress
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How do cancer-associated extrachromosomal circular DNAs arise?
In our new manuscript, we show that single-strand DNA damage in repetitive sequences can trigger i-loop formation and eccDNA generation. What started at telomeres may reflect a much broader principle across the genome and help explain how ecDNA may emerge in cancer.
https://authors.elsevier.com/a/1n0wG3vVUPZO38#eccDNA #ecDNA #CancerResearch #GenomeInstability #DNARepair #ReplicationStress
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How do cancer-associated extrachromosomal circular DNAs arise?
In our new manuscript, we show that single-strand DNA damage in repetitive sequences can trigger i-loop formation and eccDNA generation. What started at telomeres may reflect a much broader principle across the genome and help explain how ecDNA may emerge in cancer.
https://authors.elsevier.com/a/1n0wG3vVUPZO38#eccDNA #ecDNA #CancerResearch #GenomeInstability #DNARepair #ReplicationStress
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Safeguarding spermatogenesis from retrotransposon insertions by forming ecDNA.
#Transposons #Retrotransposons #ExtrachromosomalCircularDNA #ecDNA #Spermatogenesis #Drosophila #Preprint
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Safeguarding spermatogenesis from retrotransposon insertions by forming ecDNA.
#Transposons #Retrotransposons #ExtrachromosomalCircularDNA #ecDNA #Spermatogenesis #Drosophila #Preprint
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The papers, published simultaneously in Nature on Nov. 6, detail the prevalence and prognostic impact of the circles, called #ecDNA for extrachromosomal DNA, in nearly 15,000 human #cancers; highlight a novel mode of inheritance that overthrows a fundamental law of genetics; and describe an anti-cancer therapy targeting the circles that is already in clinical trials. https://mastodon.social/@ScienceScholar/113461015147098700
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The papers, published simultaneously in Nature on Nov. 6, detail the prevalence and prognostic impact of the circles, called #ecDNA for extrachromosomal DNA, in nearly 15,000 human #cancers; highlight a novel mode of inheritance that overthrows a fundamental law of genetics; and describe an anti-cancer therapy targeting the circles that is already in clinical trials. https://mastodon.social/@ScienceScholar/113461015147098700
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The papers, published simultaneously in Nature on Nov. 6, detail the prevalence and prognostic impact of the circles, called #ecDNA for extrachromosomal DNA, in nearly 15,000 human #cancers; highlight a novel mode of inheritance that overthrows a fundamental law of genetics; and describe an anti-cancer therapy targeting the circles that is already in clinical trials. https://mastodon.social/@ScienceScholar/113461015147098700
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The papers, published simultaneously in Nature on Nov. 6, detail the prevalence and prognostic impact of the circles, called #ecDNA for extrachromosomal DNA, in nearly 15,000 human #cancers; highlight a novel mode of inheritance that overthrows a fundamental law of genetics; and describe an anti-cancer therapy targeting the circles that is already in clinical trials. https://mastodon.social/@ScienceScholar/113461015147098700
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Extrachromosomal #DNA in form of tiny DNA circles could be key drivers of #cancer. It looks strangely similar to the DNA of most bacteria which is contained in single circular molecules, the bacterial chromosome.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338009/This recent paper is unfortunately behind a paywall. It is named "Extrachromosomal DNA in cancer"
https://www.nature.com/articles/s41568-024-00669-8This article is a bit more accessible. After stem cells #ecDNA is the new hope of cancer researchers
https://www.the-scientist.com/cancer-may-be-driven-by-dna-outside-of-chromosomes-68590 -
Extrachromosomal #DNA in form of tiny DNA circles could be key drivers of #cancer. It looks strangely similar to the DNA of most bacteria which is contained in single circular molecules, the bacterial chromosome.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338009/This recent paper is unfortunately behind a paywall. It is named "Extrachromosomal DNA in cancer"
https://www.nature.com/articles/s41568-024-00669-8This article is a bit more accessible. After stem cells #ecDNA is the new hope of cancer researchers
https://www.the-scientist.com/cancer-may-be-driven-by-dna-outside-of-chromosomes-68590 -
Extrachromosomal #DNA in form of tiny DNA circles could be key drivers of #cancer. It looks strangely similar to the DNA of most bacteria which is contained in single circular molecules, the bacterial chromosome.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338009/This recent paper is unfortunately behind a paywall. It is named "Extrachromosomal DNA in cancer"
https://www.nature.com/articles/s41568-024-00669-8This article is a bit more accessible. After stem cells #ecDNA is the new hope of cancer researchers
https://www.the-scientist.com/cancer-may-be-driven-by-dna-outside-of-chromosomes-68590 -
Extrachromosomal #DNA in form of tiny DNA circles could be key drivers of #cancer. It looks strangely similar to the DNA of most bacteria which is contained in single circular molecules, the bacterial chromosome.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338009/This recent paper is unfortunately behind a paywall. It is named "Extrachromosomal DNA in cancer"
https://www.nature.com/articles/s41568-024-00669-8This article is a bit more accessible. After stem cells #ecDNA is the new hope of cancer researchers
https://www.the-scientist.com/cancer-may-be-driven-by-dna-outside-of-chromosomes-68590 -
Postdoc Position in Cancer Extrachromosomal DNA Biology, Sihan Wu Lab @CRI_UTSW
A postdoc position is available in Sihan Wu lab. We study ecDNA in cancer. #postdoc #cancer #genomics #genetics #ecDNA
#ScienceJobs #job #post...
https://jobrxiv.org/job/university-of-texas-southwestern-medical-center-27778-postdoc-position-in-cancer-extrachromosomal-dna-biology-sihan-wu-lab/?feed_id=43200 -
Postdoc Position in Cancer Extrachromosomal DNA Biology, Sihan Wu Lab @CRI_UTSW
A postdoc position is available in Sihan Wu lab. We study ecDNA in cancer. #postdoc #cancer #genomics #genetics #ecDNA
#ScienceJobs #job #post...
https://jobrxiv.org/job/university-of-texas-southwestern-medical-center-27778-postdoc-position-in-cancer-extrachromosomal-dna-biology-sihan-wu-lab/?feed_id=43200 -
Postdoc Position in Cancer Extrachromosomal DNA Biology, Sihan Wu Lab @CRI_UTSW
A postdoc position is available in Sihan Wu lab. We study ecDNA in cancer. #postdoc #cancer #genomics #genetics #ecDNA
#ScienceJobs #job #post...
https://jobrxiv.org/job/university-of-texas-southwestern-medical-center-27778-postdoc-position-in-cancer-extrachromosomal-dna-biology-sihan-wu-lab/?feed_id=43200 -
Postdoc Position in Cancer Extrachromosomal DNA Biology, Sihan Wu Lab @CRI_UTSW
A postdoc position is available in Sihan Wu lab. We study ecDNA in cancer. #postdoc #cancer #genomics #genetics #ecDNA
#ScienceJobs #job #post...
https://jobrxiv.org/job/university-of-texas-southwestern-medical-center-27778-postdoc-position-in-cancer-extrachromosomal-dna-biology-sihan-wu-lab/?feed_id=43200 -
Postdoc Position in Cancer Extrachromosomal DNA Biology, Sihan Wu Lab @CRI_UTSW
A postdoc position is available in Sihan Wu lab. We study ecDNA in cancer. #postdoc #cancer #genomics #genetics #ecDNA
#ScienceJobs #job #post...
https://jobrxiv.org/job/university-of-texas-southwestern-medical-center-27778-postdoc-position-in-cancer-extrachromosomal-dna-biology-sihan-wu-lab/?feed_id=43200 -
Postdoc Position in Cancer Extrachromosomal DNA Biology, Sihan Wu Lab @CRI_UTSW
A postdoc position is available in Sihan Wu lab. We study ecDNA in cancer. #postdoc #cancer #genomics #genetics #ecDNA
#ScienceJobs #job #post...
https://jobrxiv.org/job/university-of-texas-southwestern-medical-center-27778-postdoc-position-in-cancer-extrachromosomal-dna-biology-sihan-wu-lab/?feed_id=41298 -
Postdoc Position in Cancer Extrachromosomal DNA Biology, Sihan Wu Lab @CRI_UTSW
A postdoc position is available in Sihan Wu lab. We study ecDNA in cancer. #postdoc #cancer #genomics #genetics #ecDNA
#ScienceJobs #job #post...
https://jobrxiv.org/job/university-of-texas-southwestern-medical-center-27778-postdoc-position-in-cancer-extrachromosomal-dna-biology-sihan-wu-lab/?feed_id=41298 -
Postdoc Position in Cancer Extrachromosomal DNA Biology, Sihan Wu Lab @CRI_UTSW
A postdoc position is available in Sihan Wu lab. We study ecDNA in cancer. #postdoc #cancer #genomics #genetics #ecDNA
#ScienceJobs #job #post...
https://jobrxiv.org/job/university-of-texas-southwestern-medical-center-27778-postdoc-position-in-cancer-extrachromosomal-dna-biology-sihan-wu-lab/?feed_id=41298 -
Postdoc Position in Cancer Extrachromosomal DNA Biology, Sihan Wu Lab @CRI_UTSW
A postdoc position is available in Sihan Wu lab. We study ecDNA in cancer. #postdoc #cancer #genomics #genetics #ecDNA
#ScienceJobs #job #post...
https://jobrxiv.org/job/university-of-texas-southwestern-medical-center-27778-postdoc-position-in-cancer-extrachromosomal-dna-biology-sihan-wu-lab/?feed_id=41298 -
Postdoc Position in Cancer Extrachromosomal DNA Biology, Sihan Wu Lab @CRI_UTSW
A postdoc position is available in Sihan Wu lab. We study ecDNA in cancer. #postdoc #cancer #genomics #genetics #ecDNA
#ScienceJobs #job #post...
https://jobrxiv.org/job/university-of-texas-southwestern-medical-center-27778-postdoc-position-in-cancer-extrachromosomal-dna-biology-sihan-wu-lab/?feed_id=41298 -
"Extrachromosomal DNA promotes aggressiveness of small cell lung cancer"
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"Extrachromosomal DNA promotes aggressiveness of small cell lung cancer"
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‘Bond villain’ #DNA could transform #cancer treatment, scientists say - https://www.theguardian.com/science/2023/feb/18/bond-villain-dna-could-transform-cancer-treatment-scientists-say #ecDNA #health
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‘Bond villain’ #DNA could transform #cancer treatment, scientists say - https://www.theguardian.com/science/2023/feb/18/bond-villain-dna-could-transform-cancer-treatment-scientists-say #ecDNA #health
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‘Bond villain’ #DNA could transform #cancer treatment, scientists say - https://www.theguardian.com/science/2023/feb/18/bond-villain-dna-could-transform-cancer-treatment-scientists-say #ecDNA #health
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‘Bond villain’ #DNA could transform #cancer treatment, scientists say - https://www.theguardian.com/science/2023/feb/18/bond-villain-dna-could-transform-cancer-treatment-scientists-say #ecDNA #health
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‘Bond villain’ #DNA could transform #cancer treatment, scientists say - https://www.theguardian.com/science/2023/feb/18/bond-villain-dna-could-transform-cancer-treatment-scientists-say #ecDNA #health