#stereochemistry — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #stereochemistry, aggregated by home.social.
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A new study reveals that lipid nanoparticle #stereochemistry impacts #mRNA drug delivery, with the (S,S) form of ALC315 showing similar efficacy but reduced toxicity, paving the way for improved mRNA therapies including personalized #cancer #vaccines.
https://nachrichten.idw-online.de/2025/08/01/shaping-the-future-of-mrna-based-drug-delivery -
Early in the #evolution of life a biochemical network was encapsulated within a membrane compartment. This study shows that specific #membrane forms can select for stereochemical compounds that match the pattern of #stereochemistry used by all known living things @PLOSBiology https://plos.io/4jdyLh1
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#nyt #games needs an education in #polymer #stereochemistry
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#KnowledgeByte: #Stereochemistry is the branch of chemistry concerned with the three-dimensional arrangement of atoms and molecules and the effect of this on chemical reactions.
One of it's most important application is drug design.
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In this study, #AFIR is used to calculate #retrosynthetic, or reverse, reactions going from product #molecules to starting materials. Previously, AFIR has been used to predict small, simple reactions, but accurate #stereochemistry predictions were out of reach, limiting the technique’s applicability.
#Chemistry #sflorg
https://www.sflorg.com/2022/11/chm11302201.html -
"Pasteur not only made milk safe to drink, he established the germ theory of disease, saved the French silkworm population, confronted the scourges of anthrax and rabies, and transformed the curiosity of vaccination against smallpox into a general strategy for treating and preventing human diseases."
Pasteur ranks behind only Darwin among the most exceptional biological scientists of the 19th century."
#LouisPasteur #Pasteur #Microbiology #Stereochemistry
#Bicentennialhttps://www.sciencenews.org/article/louis-pasteur-transformed-health-disease-microbiology
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My second toot to the #ChemiVerse
More reactions! Well, the same reaction as last week (if you were on Tw***er) but now with added #stereochemistry. This #SciViz summary introduces models for diastereoselective addition to C=O with α-stereocentre. There are many more models (& arguments) but hopefully useful.Might be useful to start reposting the old 1 page summaries on this new (for me) platform?
Originals are at https://www.makingmolecules.com