#ribosomal — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #ribosomal, aggregated by home.social.
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Octopus Ribosomal Mutation Gives Their Proteins a Precision Boost
https://1ban.news/octopus-ribosomal-mutation-protein-precision/
#1ban #octopus #ribosomal #mutation #protein #science -
First molecular insights into the #degradation of the #ribosomal #30S subunit.
https://phys.org/news/2024-02-molecular-insights-degradation-ribosomal-30s.html
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The discovery that a #ribosomal #protein exhibits a remarkable evolutionary transformation, with its three-dimensional structure changing drastically while its sequence remains relatively conserved.
#Biology #Microbiology #sflorg
https://www.sflorg.com/2023/12/bio12142301.html -
Comet barplots are an interesting way to underline quantitative changes (I don't know if this is how they are called). Found in a fantastic paper published last year by the Kressler group about the importance of chaperones and CCR4/NOT in correct folding and formation of #ribosomal proteins. A "tour de force" of #genetics and molecular biology in #yeast.
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As someone who identified twenty years ago some of the factors involved in the assembly of the yeast 60S #ribosomal subunit, it is fantastic to see now a structure of a pre-60S particle at its exit from the nucleus through the nuclear pore complex.
Just for fun, the name of one of the proteins that is involved in the pre-60S export is Alb1, a name that comes from "Arx1's little brother" as it is in contact with Arx1.
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When individual deletion #yeast strains cannot grow alone, some can be rescued by neighbouring strains producing a critical #metabolite. A search for cross-complementation by co-culture of mutants identified interesting links between, mostly, aminoacid synthesis pathways.
Some of the genetic interaction remain mysterious, such as those involving the deletion of #ribosomal protein genes RPS24B or RPL27A.
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A real challenging idea from the Katrin Karbstein's lab: #ribosomal proteins damaged by oxidation are replaced with "fresh" ones to maintain #ribosomes functional. For Rpl10, its association and dissociation from mature ribosomes in the cytoplasm was already known, so it is not clear if the hypothesis put forward in the paper is not a consequence of the shuttling ability of some #proteins assisted by assembly chaperones.
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Physically separating early steps in #ribosome assembly in the #Ecoli nucleoid from the RNA #degradosome attached to the inner cytoplasmic membrane protects precursor #ribosomal RNA in immature particles from degradation @Lydia_LH17 &co #PLOSBiology https://plos.io/3Qj1x2O
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Physically separating early steps in #ribosome assembly in the #Ecoli nucleoid from the RNA #degradosome attached to the inner cytoplasmic membrane protects precursor #ribosomal RNA in immature particles from degradation @Lydia_LH17 &co #PLOSBiology https://plos.io/3Qj1x2O
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Physically separating early steps in #ribosome assembly in the #Ecoli nucleoid from the RNA #degradosome attached to the inner cytoplasmic membrane protects precursor #ribosomal RNA in immature particles from degradation @Lydia_LH17 &co #PLOSBiology https://plos.io/3Qj1x2O