#ribosomes — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #ribosomes, aggregated by home.social.
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A prior @PLOSBiology study showed that P. aeruginosa can cleave the decoding center of C. elegans #ribosomes. This new study identifies the agent as Ribocin, a #nuclease that cleaves helix 69 in eukaryotic ribosomes to block translation. https://plos.io/4uiNVIa
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A prior @PLOSBiology study showed that P. aeruginosa can cleave the decoding center of C. elegans #ribosomes. This new study identifies the agent as Ribocin, a #nuclease that cleaves helix 69 in eukaryotic ribosomes to block translation. https://plos.io/4uiNVIa
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A prior @PLOSBiology study showed that P. aeruginosa can cleave the decoding center of C. elegans #ribosomes. This new study identifies the agent as Ribocin, a #nuclease that cleaves helix 69 in eukaryotic ribosomes to block translation. https://plos.io/4uiNVIa
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Can changes in the #proteome be transmitted from parents to offspring? @betowbin &co study #intergenerational effects of #DietaryRestriction in #Celegans, showing that maternal mTORC1 governs transfer of #ribosomes, so modulating growth & development @PLOSBiology https://plos.io/4tMpQJe
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Can changes in the #proteome be transmitted from parents to offspring? @betowbin &co study #intergenerational effects of #DietaryRestriction in #Celegans, showing that maternal mTORC1 governs transfer of #ribosomes, so modulating growth & development @PLOSBiology https://plos.io/4tMpQJe
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Can changes in the #proteome be transmitted from parents to offspring? @betowbin &co study #intergenerational effects of #DietaryRestriction in #Celegans, showing that maternal mTORC1 governs transfer of #ribosomes, so modulating growth & development @PLOSBiology https://plos.io/4tMpQJe
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🧬 Hidden patterns link ribosomal RNAs to genes of the nervous system
https://medicalxpress.com/news/2025-10-hidden-patterns-link-ribosomal-rnas.html
#biology #molbio #rna #brain #neuroscience #genetics #ribosomes #health #disease
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🧬 Hidden patterns link ribosomal RNAs to genes of the nervous system
https://medicalxpress.com/news/2025-10-hidden-patterns-link-ribosomal-rnas.html
#biology #molbio #rna #brain #neuroscience #genetics #ribosomes #health #disease
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🧬 Hidden patterns link ribosomal RNAs to genes of the nervous system
https://medicalxpress.com/news/2025-10-hidden-patterns-link-ribosomal-rnas.html
#biology #molbio #rna #brain #neuroscience #genetics #ribosomes #health #disease
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30S-seq redefines the bacterial Ribosome Binding Site.
#Ribosomes #30Ssubunit #ShineDalgarnoMotif #TranslationInitiation #Ecoli #Preprint
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30S-seq redefines the bacterial Ribosome Binding Site.
#Ribosomes #30Ssubunit #ShineDalgarnoMotif #TranslationInitiation #Ecoli #Preprint
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A versatile toolbox for determining IRES activity in cells and embryonic tissues.
#IRES #Ribosomes #InternalRibosomeEntrySites
https://www.embopress.org/doi/full/10.1038/s44318-025-00404-5 -
Long-term imaging of individual ribosomes reveals ribosome cooperativity in mRNA translation.
#RNA #Translation #Ribosomes
https://www.cell.com/cell/fulltext/S0092-8674(25)00045-5 -
#Ribosomes team up in difficult situations, new #imaging method reveals.
#microscopy #mRNA #translation
https://phys.org/news/2025-01-ribosomes-team-difficult-situations-imaging.html
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#Ribosomes team up in difficult situations, new #imaging method reveals.
#microscopy #mRNA #translation
https://phys.org/news/2025-01-ribosomes-team-difficult-situations-imaging.html
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#Ribosomes team up in difficult situations, new #imaging method reveals.
#microscopy #mRNA #translation
https://phys.org/news/2025-01-ribosomes-team-difficult-situations-imaging.html
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Both proteins & mRNAs have global basal-apical polarization in mouse #intestinal epithelium. Study of human intestinal cells by @SItzkovitz &co shows that while mRNAs are similarly polarized, human #mitochondria & #ribosomes are less polarized #PLOSBiology https://plos.io/3OGRZ1M
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Both proteins & mRNAs have global basal-apical polarization in mouse #intestinal epithelium. Study of human intestinal cells by @SItzkovitz &co shows that while mRNAs are similarly polarized, human #mitochondria & #ribosomes are less polarized #PLOSBiology https://plos.io/3OGRZ1M
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Both proteins & mRNAs have global basal-apical polarization in mouse #intestinal epithelium. Study of human intestinal cells by @SItzkovitz &co shows that while mRNAs are similarly polarized, human #mitochondria & #ribosomes are less polarized #PLOSBiology https://plos.io/3OGRZ1M
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28-Nov-2024
U-M, multinational team of scientists reveal structural link for initiation of #ProteinBiosynthesis in bacteriaresearchers have used advanced microscopy to image how #ribosomes recruit to #mRNA while it's being transcribed by an enzyme called RNA polymerase, or RNAP. Their results, which examine the process in bacteria, are published in the journal #Science.
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28-Nov-2024
U-M, multinational team of scientists reveal structural link for initiation of #ProteinBiosynthesis in bacteriaresearchers have used advanced microscopy to image how #ribosomes recruit to #mRNA while it's being transcribed by an enzyme called RNA polymerase, or RNAP. Their results, which examine the process in bacteria, are published in the journal #Science.
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28-Nov-2024
U-M, multinational team of scientists reveal structural link for initiation of #ProteinBiosynthesis in bacteriaresearchers have used advanced microscopy to image how #ribosomes recruit to #mRNA while it's being transcribed by an enzyme called RNA polymerase, or RNAP. Their results, which examine the process in bacteria, are published in the journal #Science.
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29-Nov-2024
#Bacteria ditch tags to dodge #antibiotics
Modified #ribosomes could be a new possible mechanism of #AntibioticResistance -
29-Nov-2024
#Bacteria ditch tags to dodge #antibiotics
Modified #ribosomes could be a new possible mechanism of #AntibioticResistance -
29-Nov-2024
#Bacteria ditch tags to dodge #antibiotics
Modified #ribosomes could be a new possible mechanism of #AntibioticResistance -
Partially or completely blocking this second process: translation in #Ribosomes is called #Ribointerference and is caused by a group called interfering RNA.
One of these is #miRNA -micro RNA-
Eukaryotic cells possibly inherited this mechanism and in most cases it has been conserved.
This has to do with something that is possibly a principle of #Physics called conservation of information. -
How cells ensure an accurate 3' end for 18S rRNA. @RobinStanleyLab explores a #PLOSBiology study which reveals multiple checkpoints that ensure only #ribosomes containing the correct 3' end participate in translation. Primer: https://plos.io/4dmcv2L Paper: https://plos.io/3UNnn2F
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How cells ensure an accurate 3' end for 18S rRNA. @RobinStanleyLab explores a #PLOSBiology study which reveals multiple checkpoints that ensure only #ribosomes containing the correct 3' end participate in translation. Primer: https://plos.io/4dmcv2L Paper: https://plos.io/3UNnn2F
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How cells ensure an accurate 3' end for 18S rRNA. @RobinStanleyLab explores a #PLOSBiology study which reveals multiple checkpoints that ensure only #ribosomes containing the correct 3' end participate in translation. Primer: https://plos.io/4dmcv2L Paper: https://plos.io/3UNnn2F
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#Microsporidia use their polar tube to infect host cells. The ultrastructure of the #PolarTube reveals different states of the tube wall, transported cargo, and uniquely arranged #ribosomes along the tube wall. @shrma_h @Barandunlab &co in #PLOSBiology https://plos.io/49wNKyt
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#Microsporidia use their polar tube to infect host cells. The ultrastructure of the #PolarTube reveals different states of the tube wall, transported cargo, and uniquely arranged #ribosomes along the tube wall. @shrma_h @Barandunlab &co in #PLOSBiology https://plos.io/49wNKyt
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#Microsporidia use their polar tube to infect host cells. The ultrastructure of the #PolarTube reveals different states of the tube wall, transported cargo, and uniquely arranged #ribosomes along the tube wall. @shrma_h @Barandunlab &co in #PLOSBiology https://plos.io/49wNKyt
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How are stalled #ribosomes rescued?
Structural and functional work by Allen Buskirk and collaborators @HopkinsMedicine finds that B. subtilis #MutS2 splits collided ribosomes via mechanisms distinct from mRNA-cleaving E. coli SmrB pathwayhttps://www.embopress.org/doi/full/10.1038/s44318-023-00010-3
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How are stalled #ribosomes rescued?
Structural and functional work by Allen Buskirk and collaborators @HopkinsMedicine finds that B. subtilis #MutS2 splits collided ribosomes via mechanisms distinct from mRNA-cleaving E. coli SmrB pathwayhttps://www.embopress.org/doi/full/10.1038/s44318-023-00010-3
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How are stalled #ribosomes rescued?
Structural and functional work by Allen Buskirk and collaborators @HopkinsMedicine finds that B. subtilis #MutS2 splits collided ribosomes via mechanisms distinct from mRNA-cleaving E. coli SmrB pathwayhttps://www.embopress.org/doi/full/10.1038/s44318-023-00010-3
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#microRNAs slow translating #ribosomes to prevent protein #misfolding in eukaryotes
Hiroaki Sako, Tadashi Yamamoto and colleagues
The unusual presence of #miRNAs targeting protein-coding sequences is shown to influence ribosome speed, thereby allowing time for accurate #polypeptide folding during protein translation.
https://www.embopress.org/doi/full/10.15252/embj.2022112469 -
#microRNAs slow translating #ribosomes to prevent protein #misfolding in eukaryotes
Hiroaki Sako, Tadashi Yamamoto and colleagues
The unusual presence of #miRNAs targeting protein-coding sequences is shown to influence ribosome speed, thereby allowing time for accurate #polypeptide folding during protein translation.
https://www.embopress.org/doi/full/10.15252/embj.2022112469 -
#microRNAs slow translating #ribosomes to prevent protein #misfolding in eukaryotes
Hiroaki Sako, Tadashi Yamamoto and colleagues
The unusual presence of #miRNAs targeting protein-coding sequences is shown to influence ribosome speed, thereby allowing time for accurate #polypeptide folding during protein translation.
https://www.embopress.org/doi/full/10.15252/embj.2022112469 -
How one of nature's most fundamental molecules forms.
https://phys.org/news/2023-07-nature-fundamental-molecules.html
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18-May-2023
A ribosomal traffic jam that breaks the heartResearchers find that deficiency in RPL3L, a ribosome expressed in heart and skeletal muscle, impairs cardiac contractility due to delayed mRNA translation
https://www.eurekalert.org/news-releases/989697 #science #nanoworld #ribosomes #proteinFolding #HeartDisease -
18-May-2023
A ribosomal traffic jam that breaks the heartResearchers find that deficiency in RPL3L, a ribosome expressed in heart and skeletal muscle, impairs cardiac contractility due to delayed mRNA translation
https://www.eurekalert.org/news-releases/989697 #science #nanoworld #ribosomes #proteinFolding #HeartDisease -
The ASC-1 complex is more than a dissociator of colliding 80S ribosomes:
Akinobu Matsumoto, Keiichi Nakayama and coworkers show that it also associates with scanning #ribosomes to promote translation initiation on a subset of transcripts
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The ASC-1 complex is more than a dissociator of colliding 80S ribosomes:
Akinobu Matsumoto, Keiichi Nakayama and coworkers show that it also associates with scanning #ribosomes to promote translation initiation on a subset of transcripts
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The ASC-1 complex is more than a dissociator of colliding 80S ribosomes:
Akinobu Matsumoto, Keiichi Nakayama and coworkers show that it also associates with scanning #ribosomes to promote translation initiation on a subset of transcripts
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#CryoEM of yeast methionine aminopeptidase & N-acetyltransferase B in complex with #ribosomes reveals involvement of rRNA expansion segment ES27a in orchestrating modifications of nascent polypeptide chains during translation @BeckmannLab #PLOSBiology https://plos.io/3n0S1an
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#CryoEM of yeast methionine aminopeptidase & N-acetyltransferase B in complex with #ribosomes reveals involvement of rRNA expansion segment ES27a in orchestrating modifications of nascent polypeptide chains during translation @BeckmannLab #PLOSBiology https://plos.io/3n0S1an
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#CryoEM of yeast methionine aminopeptidase & N-acetyltransferase B in complex with #ribosomes reveals involvement of rRNA expansion segment ES27a in orchestrating modifications of nascent polypeptide chains during translation @BeckmannLab #PLOSBiology https://plos.io/3n0S1an
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#CryoEM of yeast methionine aminopeptidase & N-acetyltransferase B in complex with #ribosomes reveals involvement of rRNA expansion segment ES27a in orchestrating modifications of nascent polypeptide chains during translation @BeckmannLab #PLOSBiology https://plos.io/3n0S1an
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#CryoEM of yeast methionine aminopeptidase & N-acetyltransferase B in complex with #ribosomes reveals involvement of rRNA expansion segment ES27a in orchestrating modifications of nascent polypeptide chains during translation @BeckmannLab #PLOSBiology https://plos.io/3n0S1an
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#CryoEM of yeast methionine aminopeptidase & N-acetyltransferase B in complex with #ribosomes reveals involvement of rRNA expansion segment ES27a in orchestrating modifications of nascent polypeptide chains during translation @BeckmannLab #PLOSBiology https://plos.io/3n0S1an
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#CryoEM of yeast methionine aminopeptidase & N-acetyltransferase B in complex with #ribosomes reveals involvement of rRNA expansion segment ES27a in orchestrating modifications of nascent polypeptide chains during translation @BeckmannLab #PLOSBiology https://plos.io/3n0S1an
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#CryoEM of yeast methionine aminopeptidase & N-acetyltransferase B in complex with #ribosomes reveals involvement of rRNA expansion segment ES27a in orchestrating modifications of nascent polypeptide chains during translation @BeckmannLab #PLOSBiology https://plos.io/3n0S1an
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#CryoEM of yeast methionine aminopeptidase & N-acetyltransferase B in complex with #ribosomes reveals involvement of rRNA expansion segment ES27a in orchestrating modifications of nascent polypeptide chains during translation @BeckmannLab #PLOSBiology https://plos.io/3n0S1an
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A real challenging idea from the Katrin Karbstein's lab: #ribosomal proteins damaged by oxidation are replaced with "fresh" ones to maintain #ribosomes functional. For Rpl10, its association and dissociation from mature ribosomes in the cytoplasm was already known, so it is not clear if the hypothesis put forward in the paper is not a consequence of the shuttling ability of some #proteins assisted by assembly chaperones.
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Human #ribosomes decode #MessengerRNA 10 times slower than bacterial ribosomes—but do so more accurately. Explore how #StJude #scientists made this discovery. http://bit.ly/3zxa9v8 #cryoEM #StructuralBiology @Nature #mRNA #StJudeResearch
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Human #ribosomes decode #MessengerRNA 10 times slower than bacterial ribosomes—but do so more accurately. Explore how #StJude #scientists made this discovery. http://bit.ly/3zxa9v8 #cryoEM #StructuralBiology @Nature #mRNA #StJudeResearch
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How do #nutrient-starved cells preserve a basal supply of dormant #ribosomes?
Michael Hall and colleagues (Biozentrum Basel) identify conserved #TORC1 #phosphorylation and inhibition of ribosome-binding factor #Stm1/#SERBP1 in #yeast and human cells
https://www.embopress.org/doi/10.15252/embj.2022112344 -
How do #nutrient-starved cells preserve a basal supply of dormant #ribosomes?
Michael Hall and colleagues (Biozentrum Basel) identify conserved #TORC1 #phosphorylation and inhibition of ribosome-binding factor #Stm1/#SERBP1 in #yeast and human cells
https://www.embopress.org/doi/10.15252/embj.2022112344