#ribosomes — Public Fediverse posts

Can changes in the #proteome be transmitted from parents to offspring? @betowbin &co study #intergenerational effects of #DietaryRestriction in #Celegans, showing that maternal mTORC1 governs transfer of #ribosomes, so modulating growth & development @PLOSBiology https://plos.io/4tMpQJe

Can changes in the #proteome be transmitted from parents to offspring? @betowbin &co study #intergenerational effects of #DietaryRestriction in #Celegans, showing that maternal mTORC1 governs transfer of #ribosomes, so modulating growth & development @PLOSBiology https://plos.io/4tMpQJe

Can changes in the #proteome be transmitted from parents to offspring? @betowbin &co study #intergenerational effects of #DietaryRestriction in #Celegans, showing that maternal mTORC1 governs transfer of #ribosomes, so modulating growth & development @PLOSBiology https://plos.io/4tMpQJe

Can changes in the #proteome be transmitted from parents to offspring? @betowbin &co study #intergenerational effects of #DietaryRestriction in #Celegans, showing that maternal mTORC1 governs transfer of #ribosomes, so modulating growth & development @PLOSBiology https://plos.io/4tMpQJe

Can changes in the #proteome be transmitted from parents to offspring? @betowbin &co study #intergenerational effects of #DietaryRestriction in #Celegans, showing that maternal mTORC1 governs transfer of #ribosomes, so modulating growth & development @PLOSBiology https://plos.io/4tMpQJe

Both proteins & mRNAs have global basal-apical polarization in mouse #intestinal epithelium. Study of human intestinal cells by @SItzkovitz &co shows that while mRNAs are similarly polarized, human #mitochondria & #ribosomes are less polarized #PLOSBiology https://plos.io/3OGRZ1M

#microRNAs slow translating #ribosomes to prevent protein #misfolding in eukaryotes
Hiroaki Sako, Tadashi Yamamoto and colleagues
The unusual presence of #miRNAs targeting protein-coding sequences is shown to influence ribosome speed, thereby allowing time for accurate #polypeptide folding during protein translation.
https://www.embopress.org/doi/full/10.15252/embj.2022112469

How do #nutrient-starved cells preserve a basal supply of dormant #ribosomes?
Michael Hall and colleagues (Biozentrum Basel) identify conserved #TORC1 #phosphorylation and inhibition of ribosome-binding factor #Stm1/#SERBP1 in #yeast and human cells
https://www.embopress.org/doi/10.15252/embj.2022112344

How do #nutrient-starved cells preserve a basal supply of dormant #ribosomes?
Michael Hall and colleagues (Biozentrum Basel) identify conserved #TORC1 #phosphorylation and inhibition of ribosome-binding factor #Stm1/#SERBP1 in #yeast and human cells
https://www.embopress.org/doi/10.15252/embj.2022112344

How do #nutrient-starved cells preserve a basal supply of dormant #ribosomes?
Michael Hall and colleagues (Biozentrum Basel) identify conserved #TORC1 #phosphorylation and inhibition of ribosome-binding factor #Stm1/#SERBP1 in #yeast and human cells
https://www.embopress.org/doi/10.15252/embj.2022112344

How do #nutrient-starved cells preserve a basal supply of dormant #ribosomes?
Michael Hall and colleagues (Biozentrum Basel) identify conserved #TORC1 #phosphorylation and inhibition of ribosome-binding factor #Stm1/#SERBP1 in #yeast and human cells
https://www.embopress.org/doi/10.15252/embj.2022112344

How do #nutrient-starved cells preserve a basal supply of dormant #ribosomes?
Michael Hall and colleagues (Biozentrum Basel) identify conserved #TORC1 #phosphorylation and inhibition of ribosome-binding factor #Stm1/#SERBP1 in #yeast and human cells
https://www.embopress.org/doi/10.15252/embj.2022112344

#Life depends on the precise functioning of several #proteins synthesized in #cells by #ribosomes. This diverse set of proteins, known as a #proteome, is maintained by the robust translation #elongation of #amino acid sequences taking place in the ribosomes.
#Biology #sflorg
https://www.sflorg.com/2023/01/bio01062301.html

@tbharat_lab is a #CryoET OG...go check out this position!

I used the data he shared from the origin #Relion subtomo paper to huge extent in developing #emClarity for my dissertation. (#ribosomes)

https://fediscience.org/@tbharat_lab/109461403525493781

Messenger #RNA (#mRNA) are biological #molecules that transfer the information coded by #genes in the nucleus to the #cytoplasm for protein synthesis by #ribosomes. mRNA sequences can be designed to encode specific proteins; the most well-known example of this is the mRNA #vaccines for #COVID-19
#Biology #Pharmaceutical #sflorg
https://www.sflorg.com/2022/11/phar11102201.html