#p53 — Public Fediverse posts

I hope everyone's watching #CancerDetectives on Channel 4!
My team has sweated over various aspects of this. It's a big passion project, my colleague's second baby, and hopefully will help more people understand what it means to do #CancerResearch today, and indeed what it means to have cancer now, compared to some decades ago.

#channel4 #cancer #cancerVaccines #BrainTumours #LiquidBiopsy #cancerOfUnknownPrimary #LungCancer #P53 #liFraumeni #5GTrial #MILITrial #DETECTION2Trial #CancerResearchUK

I hope everyone's watching #CancerDetectives on Channel 4!
My team has sweated over various aspects of this. It's a big passion project, my colleague's second baby, and hopefully will help more people understand what it means to do #CancerResearch today, and indeed what it means to have cancer now, compared to some decades ago.

#channel4 #cancer #cancerVaccines #BrainTumours #LiquidBiopsy #cancerOfUnknownPrimary #LungCancer #P53 #liFraumeni #5GTrial #MILITrial #DETECTION2Trial #CancerResearchUK

I hope everyone's watching #CancerDetectives on Channel 4!
My team has sweated over various aspects of this. It's a big passion project, my colleague's second baby, and hopefully will help more people understand what it means to do #CancerResearch today, and indeed what it means to have cancer now, compared to some decades ago.

#channel4 #cancer #cancerVaccines #BrainTumours #LiquidBiopsy #cancerOfUnknownPrimary #LungCancer #P53 #liFraumeni #5GTrial #MILITrial #DETECTION2Trial #CancerResearchUK

I hope everyone's watching #CancerDetectives on Channel 4!
My team has sweated over various aspects of this. It's a big passion project, my colleague's second baby, and hopefully will help more people understand what it means to do #CancerResearch today, and indeed what it means to have cancer now, compared to some decades ago.

#channel4 #cancer #cancerVaccines #BrainTumours #LiquidBiopsy #cancerOfUnknownPrimary #LungCancer #P53 #liFraumeni #5GTrial #MILITrial #DETECTION2Trial #CancerResearchUK

I hope everyone's watching #CancerDetectives on Channel 4!
My team has sweated over various aspects of this. It's a big passion project, my colleague's second baby, and hopefully will help more people understand what it means to do #CancerResearch today, and indeed what it means to have cancer now, compared to some decades ago.

#channel4 #cancer #cancerVaccines #BrainTumours #LiquidBiopsy #cancerOfUnknownPrimary #LungCancer #P53 #liFraumeni #5GTrial #MILITrial #DETECTION2Trial #CancerResearchUK

Elephants evolved to beat cancer, and how we could too

https://newatlas.com/biology/elephants-beat-evolution-cancer-p53-gene-petos-paradox/

#HackerNews #Elephants #Cancer #Evolution #P53 #Gene #Petos #Paradox

Elephants evolved to beat cancer, and how we could too

https://newatlas.com/biology/elephants-beat-evolution-cancer-p53-gene-petos-paradox/

#HackerNews #Elephants #Cancer #Evolution #P53 #Gene #Petos #Paradox

Elephants evolved to beat cancer, and how we could too

https://newatlas.com/biology/elephants-beat-evolution-cancer-p53-gene-petos-paradox/

#HackerNews #Elephants #Cancer #Evolution #P53 #Gene #Petos #Paradox

Elephants evolved to beat cancer, and how we could too

https://newatlas.com/biology/elephants-beat-evolution-cancer-p53-gene-petos-paradox/

#HackerNews #Elephants #Cancer #Evolution #P53 #Gene #Petos #Paradox

The protein #p53, known as the "guardian of the genome," plays a crucial role in preventing #cancer. When it malfunctions, tumors can form. Scientists are developing drugs to restore or mimic p53's function in cancer cells. A #biology researcher explains:
https://theconversation.com/p53-is-both-your-genomes-guardian-and-weakness-against-cancer-scientists-are-trying-to-repair-or-replace-it-when-it-goes-awry-248674 #science

Extra #centrosomes are initially anti-#tumorigenic but why?
Irmina Garcia-Carpio, Andreas Villunger et al find that through #PIDDosome activation, they not only induce #p53 responses, but also #NFkB signaling to increase #immunogenicity of cancer cells
https://www.embopress.org/doi/full/10.15252/embj.2023113510

Extra #centrosomes are initially anti-#tumorigenic but why?
Irmina Garcia-Carpio, Andreas Villunger et al find that through #PIDDosome activation, they not only induce #p53 responses, but also #NFkB signaling to increase #immunogenicity of cancer cells
https://www.embopress.org/doi/full/10.15252/embj.2023113510

Extra #centrosomes are initially anti-#tumorigenic but why?
Irmina Garcia-Carpio, Andreas Villunger et al find that through #PIDDosome activation, they not only induce #p53 responses, but also #NFkB signaling to increase #immunogenicity of cancer cells
https://www.embopress.org/doi/full/10.15252/embj.2023113510

Extra #centrosomes are initially anti-#tumorigenic but why?
Irmina Garcia-Carpio, Andreas Villunger et al find that through #PIDDosome activation, they not only induce #p53 responses, but also #NFkB signaling to increase #immunogenicity of cancer cells
https://www.embopress.org/doi/full/10.15252/embj.2023113510

Tatsuki Tsuruoka, Kazuyasu Sakaguchi, Toshiaki Imagawa and colleagues share their reporter system for visualising transcriptional activity of p53 at the single cell level.

https://journals.biologists.com/jcs/article/136/12/jcs260918/316739/Development-of-a-fluorescence-reporter-system-to

#cellbiology #p53

In single pancreatic cells responding to oxidative stress, JNK dynamics regulate an early trigger of cell death, #p53 controls late maintenance of cell cycle arrest &p38 controls a switch between JNK- and p53-dependent cell fate➡️ http://bit.ly/3UPf6YM E Batchelor (UMN Medical School) #QBio #cellfate #SystemsBiology

In single pancreatic cells responding to oxidative stress, JNK dynamics regulate an early trigger of cell death, #p53 controls late maintenance of cell cycle arrest &p38 controls a switch between JNK- and p53-dependent cell fate➡️ http://bit.ly/3UPf6YM E Batchelor (UMN Medical School) #QBio #cellfate #SystemsBiology