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#metformin — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #metformin, aggregated by home.social.

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  1. Enttäuschender Medizinjournalismus

    Medizinportale berichten von einer Studie, laut der bei #COVID19 eingenommenes #Metformin das Risiko, an #LongCovid halbiere.

    Tatsächlich zeigte die Studie, die einige Probleme hat, leider keine signifikante Wirkung. Lediglich ein sekundärer Endpunkt ("klinisch diagnostiziertes Long Covid") war positiv, allerdings mit einem enorm hohen Konfidenzintervall - risk ratio 0.495 (95% CrI 0.155 to 0.995).

    Vielleicht werden zukünftige Studien ein Wirksamkeit von Metformin belegen. Hinweise dafür gibt es ja einige. Aber wenn Studienergebnisse so selektiv wiedergegeben werden, ohne auf den Unterschied primärer vs sekundärer Endpunkt oder auf Konfidenzintervalle einzugehen, dann ist das Ahnungslosigkeit oder Propaganda.

    Die Studie:
    academic.oup.com/cid/advance-a

  2. Enttäuschender Medizinjournalismus

    Medizinportale berichten von einer Studie, laut der bei #COVID19 eingenommenes #Metformin das Risiko, an #LongCovid halbiere.

    Tatsächlich zeigte die Studie, die einige Probleme hat, leider keine signifikante Wirkung. Lediglich ein sekundärer Endpunkt ("klinisch diagnostiziertes Long Covid") war positiv, allerdings mit einem enorm hohen Konfidenzintervall - risk ratio 0.495 (95% CrI 0.155 to 0.995).

    Vielleicht werden zukünftige Studien ein Wirksamkeit von Metformin belegen. Hinweise dafür gibt es ja einige. Aber wenn Studienergebnisse so selektiv wiedergegeben werden, ohne auf den Unterschied primärer vs sekundärer Endpunkt oder auf Konfidenzintervalle einzugehen, dann ist das Ahnungslosigkeit oder Propaganda.

    Die Studie:
    academic.oup.com/cid/advance-a

  3. Metformin, the diabetes drug that has been thought to suppress glucose production in the liver, instead inhibits mitochondria in the gut, causing the gut to increase its consumption (and breakdown) of glucose.

    Summary: refractor.io/diabetes/metformi

    Original paper: nature.com/articles/s42255-026

    #Science #Metformin #Diabetes #Metabolism

  4. Metformin, the diabetes drug that has been thought to suppress glucose production in the liver, instead inhibits mitochondria in the gut, causing the gut to increase its consumption (and breakdown) of glucose.

    Summary: refractor.io/diabetes/metformi

    Original paper: nature.com/articles/s42255-026

    #Science #Metformin #Diabetes #Metabolism

  5. Metformin Raises Exercise-Associated Metabolite Lac-Phe in Prostate Cancer Patients on Hormone Therapy

    📰 Original title: Diabetes Drug, Metformin, May Echo the Benefits of Exercise in Prostate Cancer Care

    🤖 IA: It's not clickbait ✅
    👥 Usuarios: It's not clickbait ✅

    View full AI summary: killbait.com/en/metformin-rais

    #health #metformin #prostate...

  6. Metformin Raises Exercise-Associated Metabolite Lac-Phe in Prostate Cancer Patients on Hormone Therapy

    📰 Original title: Diabetes Drug, Metformin, May Echo the Benefits of Exercise in Prostate Cancer Care

    🤖 IA: It's not clickbait ✅
    👥 Usuarios: It's not clickbait ✅

    View full AI summary: killbait.com/en/metformin-rais

    #health #metformin #prostate...

  7. After 60+ years, the common diabetes drug metformin has been found to unexpectedly affect the brain.
    A new study shows it targets the protein Rap1 in the ventromedial hypothalamus, activating SF1 neurons to help lower blood glucose — and it works at much lower concentrations in the brain than in the body.
    Promising findings that could lead to better treatments for glucose control and possibly brain protection.

    #Metformin #Diabetes #BrainHealth #MedicalResearch #Prediabetes

    sciencealert.com/after-60-year

  8. After 60+ years, the common diabetes drug metformin has been found to unexpectedly affect the brain.
    A new study shows it targets the protein Rap1 in the ventromedial hypothalamus, activating SF1 neurons to help lower blood glucose — and it works at much lower concentrations in the brain than in the body.
    Promising findings that could lead to better treatments for glucose control and possibly brain protection.

    #Metformin #Diabetes #BrainHealth #MedicalResearch #Prediabetes

    sciencealert.com/after-60-year

  9. THREAT MODEL: COVID 🦠
    for Mar. 12th, 2026
    by independent journalist @violetblue

    - #USmilitary study concludes 42% of #Covid infections lead to #LongCovid "regardless of initial disease severity”

    - RFK’s #MAHA Institute calls to eliminate all childhood vaccines

    - A new Long Covid treatment guide

    - Babies with Covid “develop more serious disease than those with RSV”

    - Trump admin removes more Covid datasets

    - #Aotearoa #NewZealand ’s new Covid report smothered by disinformation

    - #AotearoaNZ vaccinologist: repeat infection is “accumulating damage”

    - Study: #Metformin reduces Long Covid risk but not an effective LC treatment

    - US survey: only 26 of 400 Long Covid clinics remain

    ...and much more.

    ✨THREAT MODEL is free to read -- please help keep it accessible to all by becoming a patron, even $1 a month makes a difference!✨

    patreon.com/posts/covid-march-

    #ThreatModel #ThreatModelCovid #ThreatModelNewsletters #VioletBlue #COVIDnews #PublicHealth #CovidIsNotOver

  10. THREAT MODEL: COVID 🦠
    for Mar. 12th, 2026
    by independent journalist @violetblue

    - #USmilitary study concludes 42% of #Covid infections lead to #LongCovid "regardless of initial disease severity”

    - RFK’s #MAHA Institute calls to eliminate all childhood vaccines

    - A new Long Covid treatment guide

    - Babies with Covid “develop more serious disease than those with RSV”

    - Trump admin removes more Covid datasets

    - #Aotearoa #NewZealand ’s new Covid report smothered by disinformation

    - #AotearoaNZ vaccinologist: repeat infection is “accumulating damage”

    - Study: #Metformin reduces Long Covid risk but not an effective LC treatment

    - US survey: only 26 of 400 Long Covid clinics remain

    ...and much more.

    ✨THREAT MODEL is free to read -- please help keep it accessible to all by becoming a patron, even $1 a month makes a difference!✨

    patreon.com/posts/covid-march-

    #ThreatModel #ThreatModelCovid #ThreatModelNewsletters #VioletBlue #COVIDnews #PublicHealth #CovidIsNotOver

  11. 𝙏𝙝𝙧𝙚𝙖𝙩 𝙈𝙤𝙙𝙚𝙡: 𝘾𝙤𝙫𝙞𝙙
    𝘧𝘰𝘳 Feb. 5th, 2026
    𝘣𝘺 𝘫𝘰𝘶𝘳𝘯𝘢𝘭𝘪𝘴𝘵 @violetblue

    - Trends suggest US is in for a second #Covid surge

    - First vaccine targeting #SARS virus family enters human trials

    - Even more evidence showing #metformin prevents #LongCovid

    - Australian #WinterOlympics team staff test positive for Covid ahead of #WinterOlympics2026 Milano Cortina Games

    - Four #EU orgs form international federation Long COVID Rise Up

    - Largest pediatric Long Covid trial to launch this year

    - Many older US adults haven’t had recent flu or Covid vaccine

    - Large study finds Covid shots don’t affect fertility (but catching Covid does)

    - New study: Covid in pregnancy linked w/risk of childhood neurodevelopmental disorders

    ...and much more.

    * 𝙏𝙝𝙧𝙚𝙖𝙩 𝙈𝙤𝙙𝙚𝙡 𝘪𝘴 𝘧𝘳𝘦𝘦 𝘵𝘰 𝘳𝘦𝘢𝘥 -- 𝘱𝘭𝘦𝘢𝘴𝘦 𝘩𝘦𝘭𝘱 𝘬𝘦𝘦𝘱 𝘪𝘵 𝘢𝘤𝘤𝘦𝘴𝘴𝘪𝘣𝘭𝘦 𝘵𝘰 𝘢𝘭𝘭 𝘣𝘺 𝘣𝘦𝘤𝘰𝘮𝘪𝘯𝘨 𝘢 𝘱𝘢𝘵𝘳𝘰𝘯, 𝘦𝘷𝘦𝘯 $1/𝘮𝘰𝘯𝘵𝘩 𝘮𝘢𝘬𝘦𝘴 𝘢 𝘥𝘪𝘧𝘧𝘦𝘳𝘦𝘯𝘤𝘦 *

    patreon.com/posts/covid-februa

    #ThreatModel #ThreatModelCovid #ThreatModelNewsletters #VioletBlue #COVIDnews #PublicHealth #CovidIsNotOver

  12. 𝙏𝙝𝙧𝙚𝙖𝙩 𝙈𝙤𝙙𝙚𝙡: 𝘾𝙤𝙫𝙞𝙙
    𝘧𝘰𝘳 Feb. 5th, 2026
    𝘣𝘺 𝘫𝘰𝘶𝘳𝘯𝘢𝘭𝘪𝘴𝘵 @violetblue

    - Trends suggest US is in for a second #Covid surge

    - First vaccine targeting #SARS virus family enters human trials

    - Even more evidence showing #metformin prevents #LongCovid

    - Australian #WinterOlympics team staff test positive for Covid ahead of #WinterOlympics2026 Milano Cortina Games

    - Four #EU orgs form international federation Long COVID Rise Up

    - Largest pediatric Long Covid trial to launch this year

    - Many older US adults haven’t had recent flu or Covid vaccine

    - Large study finds Covid shots don’t affect fertility (but catching Covid does)

    - New study: Covid in pregnancy linked w/risk of childhood neurodevelopmental disorders

    ...and much more.

    * 𝙏𝙝𝙧𝙚𝙖𝙩 𝙈𝙤𝙙𝙚𝙡 𝘪𝘴 𝘧𝘳𝘦𝘦 𝘵𝘰 𝘳𝘦𝘢𝘥 -- 𝘱𝘭𝘦𝘢𝘴𝘦 𝘩𝘦𝘭𝘱 𝘬𝘦𝘦𝘱 𝘪𝘵 𝘢𝘤𝘤𝘦𝘴𝘴𝘪𝘣𝘭𝘦 𝘵𝘰 𝘢𝘭𝘭 𝘣𝘺 𝘣𝘦𝘤𝘰𝘮𝘪𝘯𝘨 𝘢 𝘱𝘢𝘵𝘳𝘰𝘯, 𝘦𝘷𝘦𝘯 $1/𝘮𝘰𝘯𝘵𝘩 𝘮𝘢𝘬𝘦𝘴 𝘢 𝘥𝘪𝘧𝘧𝘦𝘳𝘦𝘯𝘤𝘦 *

    patreon.com/posts/covid-februa

    #ThreatModel #ThreatModelCovid #ThreatModelNewsletters #VioletBlue #COVIDnews #PublicHealth #CovidIsNotOver

  13. CW: Diabetes Request to share experiences with semaglutide

    My #endocrinologist still can't make up their mind whether I have #diabetes type 1 or type 2 because #COVID19 gave me diabetes. They switched me from #insulin to #metformin and it's working pretty well. They plan to add some #glp1 agonist at some point down the road. Not sure about that though. I know that both insulin and #Semaglutid are hormons that are native to the body. But I just feel (maybe irrational) apprehension towards drugs like #ozempic. Any fellow #diabetic got some experiences to share?

  14. CW: Diabetes Request to share experiences with semaglutide

    My #endocrinologist still can't make up their mind whether I have #diabetes type 1 or type 2 because #COVID19 gave me diabetes. They switched me from #insulin to #metformin and it's working pretty well. They plan to add some #glp1 agonist at some point down the road. Not sure about that though. I know that both insulin and #Semaglutid are hormons that are native to the body. But I just feel (maybe irrational) apprehension towards drugs like #ozempic. Any fellow #diabetic got some experiences to share?

  15. @unchartedworlds @EricCarroll No, that's right, and it is super cheap.

    It's really interesting that #metformin seems to have antiviral effects, given the reduction in viral load reported there. I wonder what other viruses it effects similarly?

    #covid #LongCovid

  16. @unchartedworlds @EricCarroll No, that's right, and it is super cheap.

    It's really interesting that #metformin seems to have antiviral effects, given the reduction in viral load reported there. I wonder what other viruses it effects similarly?

    #covid #LongCovid

  17. Last week, I had another check-up by our company physician.(*)

    The _last_ one, three years ago, ended very dramatically - the physician called me the next day and told me that my blood sugar values were so high that I should check in with a clinic _right now_.

    I did so, stayed there for two nights(**), got some #insulin injections, got out, had a few further medical checkups, and took #metformin for a year.

    I also had a few appointments with a nutritionist who explained a few things to me. I then made a few changes to my diet and my exercise habits.

    After that year had passed, my blood sugar levels were low enough that my #diabetes could be considered in full remission, and I stopped taking the pills - although I still check my blood sugar values regularly.

    I didn't get my full evaluation yet. However, I did learn that my eyesight is a lot better than three years ago - back then, I was told that I shouldn't drive without glasses (which was easy to do, since I don't drive cars anyway). Now I have full vision again at both long and intermediate ranges, although I need reading glasses on short distances (which I already knew).

    So while it's not always possible to control all aspects of one's health, I _am_ pretty glad I managed to control _this_ one.

    (*) For the record, I live in a country where it is illegal for my employer to know any medical details about me other than the minimum necessary - such as "This person is sick, and cannot come to work this week". So while this physician was hired by our company to do these (voluntary) checkups, he does maintain patient confidentiality.

    (**) Total out-of-pocket costs: €30, plus another €15 for WLAN access.

  18. Last week, I had another check-up by our company physician.(*)

    The _last_ one, three years ago, ended very dramatically - the physician called me the next day and told me that my blood sugar values were so high that I should check in with a clinic _right now_.

    I did so, stayed there for two nights(**), got some #insulin injections, got out, had a few further medical checkups, and took #metformin for a year.

    I also had a few appointments with a nutritionist who explained a few things to me. I then made a few changes to my diet and my exercise habits.

    After that year had passed, my blood sugar levels were low enough that my #diabetes could be considered in full remission, and I stopped taking the pills - although I still check my blood sugar values regularly.

    I didn't get my full evaluation yet. However, I did learn that my eyesight is a lot better than three years ago - back then, I was told that I shouldn't drive without glasses (which was easy to do, since I don't drive cars anyway). Now I have full vision again at both long and intermediate ranges, although I need reading glasses on short distances (which I already knew).

    So while it's not always possible to control all aspects of one's health, I _am_ pretty glad I managed to control _this_ one.

    (*) For the record, I live in a country where it is illegal for my employer to know any medical details about me other than the minimum necessary - such as "This person is sick, and cannot come to work this week". So while this physician was hired by our company to do these (voluntary) checkups, he does maintain patient confidentiality.

    (**) Total out-of-pocket costs: €30, plus another €15 for WLAN access.

  19. #Gesundheit #Langlebigkeit
    #Diabetes

    *Gängiges Medikament könnte Lebenserwartung von Frauen erhöhen*

    (2/2)

    👉Das Medikament kann verschiedene #Alterungsprozesse im Körper verlangsamen. Studien bescheinigen ihm etwa, #DNA-Schäden zu reduzieren oder Gene zu aktivieren, die mit #Langlebigkeit in Verbindung stehen. Frühere Arbeiten deuteten auch darauf hin, dass #Metformin den altersbedingten Abbau des #Gehirns verlangsamen und sogar das Risiko für #LongCovid senken könnte... 👈"

    //

    @de

  20. #Gesundheit #Langlebigkeit
    #Diabetes

    *Gängiges Medikament könnte Lebenserwartung von Frauen erhöhen*

    (2/2)

    👉Das Medikament kann verschiedene #Alterungsprozesse im Körper verlangsamen. Studien bescheinigen ihm etwa, #DNA-Schäden zu reduzieren oder Gene zu aktivieren, die mit #Langlebigkeit in Verbindung stehen. Frühere Arbeiten deuteten auch darauf hin, dass #Metformin den altersbedingten Abbau des #Gehirns verlangsamen und sogar das Risiko für #LongCovid senken könnte... 👈"

    //

    @de

  21. #Gesundheit #Langlebigkeit
    #Diabetes

    *Gängiges Medikament könnte Lebenserwartung von Frauen erhöhen*

    (1/2)

    "Trotz einiger Einschränkungen der Studie zeigte die Auswertung: 👉Frauen, die #Metformin erhielten, hatten ein rund 30 Prozent geringeres Risiko, vor ihrem 90. Geburtstag zu sterben👈 als jene, die mit einem anderen #Diabetesmittel behandelt wurden."

    "Metformin ist seit Jahrzehnten auf dem Markt und gilt als #Gerotherapeutikum...

    europesays.com/de/597383/

    @de

  22. #Gesundheit #Langlebigkeit
    #Diabetes

    *Gängiges Medikament könnte Lebenserwartung von Frauen erhöhen*

    (1/2)

    "Trotz einiger Einschränkungen der Studie zeigte die Auswertung: 👉Frauen, die #Metformin erhielten, hatten ein rund 30 Prozent geringeres Risiko, vor ihrem 90. Geburtstag zu sterben👈 als jene, die mit einem anderen #Diabetesmittel behandelt wurden."

    "Metformin ist seit Jahrzehnten auf dem Markt und gilt als #Gerotherapeutikum...

    europesays.com/de/597383/

    @de

  23. RE: mastodon.social/@ScienceSchola

    Don't let the dire-sounding headline confuse you. This all sounds like good news (I've been taking the stuff for about at least eight years now). The stuff still works, and the possible side effects discussed are GOOD and make more sense now.

    #diabetes #medicine #medications #metformin

  24. RE: mastodon.social/@ScienceSchola

    Don't let the dire-sounding headline confuse you. This all sounds like good news (I've been taking the stuff for about at least eight years now). The stuff still works, and the possible side effects discussed are GOOD and make more sense now.

    #diabetes #medicine #medications #metformin

  25. 💊💉👩‍⚕️🏥⚕️🥼🩺🧘‍♀️🩻😷⛑️⚖️👩‍🔬🌗🌐🧬🧫✂️🥼🧪🔬🧲💁‍♀️*After 60 Years, Diabetes Drug Found to Unexpectedly Affect The Brain👉

    #Metformin #Brain #Help

    After 60 Years, Diabetes Drug Found to Unexpectedly Affect The Brain : ScienceAlert sciencealert.com/after-60-year

  26. A double-blind clinical trial of the effect of metformin on exercise response, in 72 adults at risk for diabetes and heart disease, confirmed that metformin counters the beneficial effects of exercise, possibly though its action of blocking mitochondrial activity.

    Summary: scienceblog.com/when-exercise-

    Original paper (not open access): academic.oup.com/jcem/advance-

    #Science #Health #Diabetes #CVD #Exercise #Metformin

  27. A double-blind clinical trial of the effect of metformin on exercise response, in 72 adults at risk for diabetes and heart disease, confirmed that metformin counters the beneficial effects of exercise, possibly though its action of blocking mitochondrial activity.

    Summary: scienceblog.com/when-exercise-

    Original paper (not open access): academic.oup.com/jcem/advance-

    #Science #Health #Diabetes #CVD #Exercise #Metformin

  28. #metformin

    "After 60 Years, Diabetes Drug Found to Unexpectedly Impact The Brain

    Metformin has been prescribed to people with type 2 diabetes to manage blood sugar for more than 60 years, but scientists haven't been exactly sure how it works. A new study suggests it works directly in the brain, which could lead to new types of treatment."

    sciencealert.com/after-60-year

  29. #metformin

    "After 60 Years, Diabetes Drug Found to Unexpectedly Impact The Brain

    Metformin has been prescribed to people with type 2 diabetes to manage blood sugar for more than 60 years, but scientists haven't been exactly sure how it works. A new study suggests it works directly in the brain, which could lead to new types of treatment."

    sciencealert.com/after-60-year

  30. A Perspective on the Role of Metformin in Treating Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Long COVID
    pubs.acs.org/doi/full/10.1021/

    lots of details on #pathophysiology in this review

    #MECFS #LongCovid #metformin #DrugRepurposing #medicine #health
    #WASF3

  31. Another paper about AMPK. This gives a good overview as well as information about AMPK activation.

    Takeaway: If you wish you had access to Metformin but don't, you might want to look into what this paper says about AMPK activation.

    pmc.ncbi.nlm.nih.gov/articles/

    #AMPK #Metformin

    #AMPK #Longevity #PublicHealth

  32. Another paper about AMPK. This gives a good overview as well as information about AMPK activation.

    Takeaway: If you wish you had access to Metformin but don't, you might want to look into what this paper says about AMPK activation.

    pmc.ncbi.nlm.nih.gov/articles/

    #AMPK #Metformin

    #AMPK #Longevity #PublicHealth

  33. Seit 15 Jahren wird mein #diabetestype2 mit einem Kombipräparat aus #Metformin behandelt und lag immer beim #hba1c um die 6%. Durch die Sportabstinenz des letzten halben Jahres ist er auf 8,5 % geklettert. Mein Hausarzt hat mir daher zusätzlich "Jardiance", einen SGLT2-Hemmer verordnet, den ich nun seit 14 Tagen nehme. Neben einem #Gewichtsverlust von aktuell 2,3 kg ist auch mein Blutdruck deutlich nach unten gegangen.
    Nimmt hier auch jemand dieses Mittel und hat evtl. Langzeiterfahrung?