#genomefolding — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #genomefolding, aggregated by home.social.
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Out today in Nature Methods: our manuscript outlining improvements we've made to Genome Architecture Mapping (GAM) and comparisons between GAM and Hi-C.TLDR: We made GAM much cheaper, show that it performs better than Hi-C at detecting complex interactions and identify a class of CTCF-enhancer interactions that are poorly detected by Hi-C. Paper at https://doi.org/10.1038/s41592-023-01903-1 and the story behind the work at https://protocolsmethods.springernature.com/posts/appreciating-the-complexity-of-dna-folding #genomics #GenomeFolding #epigenetics #paper #ctcf #HiC