#apobec — Public Fediverse posts

The bad:

"Nevertheless, these mechanisms yield viral selection. APOBEC expression in cancers leads to DNA damage and tumor cell death, yet allows for immune escape variants."

The verdict:

"Indeed, APOBECs are fickle friends."

#mutation
#cancer
#Apobec
#viruses
#virology
#RNAediting

"We identified and validated APOBEC3A and APOBEC4 as novel #ribosome biogenesis factors through our laboratory's established screening platform for the discovery of regulators of nucleolar function in MCF10A cells."

#Apobec #preprint

https://www.biorxiv.org/content/10.1101/2023.02.20.529126v1