#rnaediting — Public Fediverse posts

https://www.europesays.com/ie/234700/ RNA editing study finds many ways for neurons to diversify | MIT News #ADAR #AndresCrane #CellularAndMolecularBiology #complexin #Éire #GlutamateRelease #IE #Ireland #MITBCS #MITBiology #MITPicowerInstitute #NonCanonicalEdits #RNAEditing #RNATranscripts #Science #SynapticPlasticity #TroyLittleton

🧠 Could reprogramming RNA offer a new path to brain aneurysm therapies?

🔗 In-depth analysis of the RNA editing landscape in intracranial aneurysms and its potential role in alternative splicing. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.09.021

📚 CSBJ: https://www.csbj.org/

#RNAediting #IntracranialAneurysm #Neuroscience #Genomics #PrecisionMedicine #MedicalResearch #BrainHealth #StrokeResearch

https://www.europesays.com/uk/113324/ Expands Genetic Hearing Loss Pipeline with $1.3B RNA Therapy Partnership #EliLillyAndCompany #GeneTherapies #Genetics #HearingLoss #RNAEditing #RNATherapeutics #Science #SensorineuralHearingLoss #UK #UnitedKingdom

Wissenschaftliche #Hypothesen zu formulieren, ist leicht. Die meisten davon – auch sehr plausible – landen indes auf dem Kaffeetisch, weil man sie nicht mit Experimenten testen kann. Zwei Beispiele zur #Drosophila-Ernährung und zum #RNAEditing bei Tintenfischen: https://www.laborjournal.de/editorials/3224.php

Manch evolutionärer Wandel geschieht völlig ohne Selektions- und Anpassungsdruck. In unserer Freitags-Kolumne erklären wir das genauer an den Beispielen "Fliegende Toaster" und "#RNAEditing": 👉 https://www.laborjournal.de/editorials/2851.php #Evolution

"Machine learning and deep learning are showing their strength in genomics because they can take advantage of the huge datasets that can now be generated by modern high-throughput experiments. Importantly, we were also able to use 'interpretable machine learning' to understand why the model predicts that a specific guide will work well" #biotechnology #CRISPR #Genetics #MolecularBiology #RNAediting https://phys.org/news/2023-06-ai-combined-crispr-precisely-gene.html

The bad:

"Nevertheless, these mechanisms yield viral selection. APOBEC expression in cancers leads to DNA damage and tumor cell death, yet allows for immune escape variants."

The verdict:

"Indeed, APOBECs are fickle friends."

#mutation
#cancer
#Apobec
#viruses
#virology
#RNAediting

#Squid edit their RNA to keep cellular supply lines moving in the cold. Changing the genetic material may allow the #cephalopods to rapidly adjust to temperature swings https://www.sciencenews.org/article/squid-edit-rna-cold-adaptation

[#preprint] RNA recoding in cephalopods tailors #microtubule motor protein function https://www.biorxiv.org/content/10.1101/2022.09.25.509396v1

"In these #animals, 60 percent or more of their #proteins are actually recoded. This is astonishing in comparison to how rarely #RNAediting is used in #mammals"