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#aldehydehypothesis — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #aldehydehypothesis, aggregated by home.social.

  1. Rhyothemis @[email protected] ·
    CW: The Aldehyde Hypothesis | Heran Darwin

    I came across a study* by way of a video** on glutathione that reported increased GSH enhanced mycobacterium clearance. Given that the treatment reduced malondialdehyde - how does this fit in with the aldehyde hypothesis?

    * doi.org/10.3390/antiox12071375
    ** youtu.be/P5Z5RaBOLvw?si=GHzaDW

    #glutathione #mycobacteria
    #aldehydes #AldehydeHypothesis
    #tuberculosis #microbiology #immunology

    #tuberculosis #glutathione #mycobacteria #aldehydes #aldehydehypothesis #microbiology
  2. Rhyothemis @[email protected] ·
    CW: The Aldehyde Hypothesis | Heran Darwin

    NIH presentation, Sept 27, 2023
    youtu.be/zLkq6a_W1nE?si=1GTVQA

    Reactive aldehydes enhance the antimicrobial effect of nitric oxide - possibly an explanation for the maintenance of ALDH2* in Asian populations.
    Acetaldehyde doesn't work - so drinking alcohol won't help treat TB infection.
    Warburg Effect - anaerobic glycolysis produces aldehydes (methylglyoxal) [22:12, 54:26].

    #ALDH2 #NitricOxide
    #Tuberculosis
    #Microbiology
    #Immunology #malondialdehyde #methylglyoxal #metabolism #WarburgEffect #Immunometabolism
    #AldehydeHypothesis

    #aldh2 #nitricoxide #tuberculosis #microbiology #immunology #malondialdehyde