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#p450 — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #p450, aggregated by home.social.

  1. "We examined how these #flavonoids are #oxidized by human #P450 family 1 and 2A #enzymes. Naringenin was principally oxidized at the 3′-position to form eriodictyol by CYP1 enzymes more efficiently than by CYP2A enzymes, and the resulting eriodictyol was further oxidized to two penta-hydroxylated products. In contrast to plant P450 enzymes, these human P450s did not mediate the desaturation of naringenin and eriodictyol to give apigenin and luteolin, respectively."

    pubs.acs.org/doi/10.1021/acs.c