#nucleicacids — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #nucleicacids, aggregated by home.social.
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🧬 If structure determines function, how can we optimize DNA therapeutics without accurately predicting their 3D shape?
🔗 Predicting Single-Stranded DNA Oligonucleotides 3D Structures: An Open Issue. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0127
📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj
#StructuralBiology #DNA #ComputationalBiology #Bioinformatics #MolecularBiology #Aptamers #DNANanotechnology #GenomeEngineering #NucleicAcids
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🧬 If structure determines function, how can we optimize DNA therapeutics without accurately predicting their 3D shape?
🔗 Predicting Single-Stranded DNA Oligonucleotides 3D Structures: An Open Issue. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0127
📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj
#StructuralBiology #DNA #ComputationalBiology #Bioinformatics #MolecularBiology #Aptamers #DNANanotechnology #GenomeEngineering #NucleicAcids
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🧬 If structure determines function, how can we optimize DNA therapeutics without accurately predicting their 3D shape?
🔗 Predicting Single-Stranded DNA Oligonucleotides 3D Structures: An Open Issue. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0127
📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj
#StructuralBiology #DNA #ComputationalBiology #Bioinformatics #MolecularBiology #Aptamers #DNANanotechnology #GenomeEngineering #NucleicAcids
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🧬 If structure determines function, how can we optimize DNA therapeutics without accurately predicting their 3D shape?
🔗 Predicting Single-Stranded DNA Oligonucleotides 3D Structures: An Open Issue. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0127
📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj
#StructuralBiology #DNA #ComputationalBiology #Bioinformatics #MolecularBiology #Aptamers #DNANanotechnology #GenomeEngineering #NucleicAcids
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🧬 If structure determines function, how can we optimize DNA therapeutics without accurately predicting their 3D shape?
🔗 Predicting Single-Stranded DNA Oligonucleotides 3D Structures: An Open Issue. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0127
📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj
#StructuralBiology #DNA #ComputationalBiology #Bioinformatics #MolecularBiology #Aptamers #DNANanotechnology #GenomeEngineering #NucleicAcids
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For anyone interested in, or working on, #NucleicAcids (in the broadest sense), we have just launched a new innovation network.
Details in the link, including how to sign up.
As this is a new network, with a broad remit, there is an opportunity to help shape its activities and priorities.
We also have some funds for training and network building activities coming along later.
The network is not exclusive to UK-participants and we welcome international colleagues.
https://www.ncl.ac.uk/press/articles/latest/2026/05/nucleicacidnetwork/ -
For anyone interested in, or working on, #NucleicAcids (in the broadest sense), we have just launched a new innovation network.
Details in the link, including how to sign up.
As this is a new network, with a broad remit, there is an opportunity to help shape its activities and priorities.
We also have some funds for training and network building activities coming along later.
The network is not exclusive to UK-participants and we welcome international colleagues.
https://www.ncl.ac.uk/press/articles/latest/2026/05/nucleicacidnetwork/ -
For anyone interested in, or working on, #NucleicAcids (in the broadest sense), we have just launched a new innovation network.
Details in the link, including how to sign up.
As this is a new network, with a broad remit, there is an opportunity to help shape its activities and priorities.
We also have some funds for training and network building activities coming along later.
The network is not exclusive to UK-participants and we welcome international colleagues.
https://www.ncl.ac.uk/press/articles/latest/2026/05/nucleicacidnetwork/ -
For anyone interested in, or working on, #NucleicAcids (in the broadest sense), we have just launched a new innovation network.
Details in the link, including how to sign up.
As this is a new network, with a broad remit, there is an opportunity to help shape its activities and priorities.
We also have some funds for training and network building activities coming along later.
The network is not exclusive to UK-participants and we welcome international colleagues.
https://www.ncl.ac.uk/press/articles/latest/2026/05/nucleicacidnetwork/ -
We keep finding the raw material of #DNA in #asteroids—what's it telling us?
There are four #nucleicacids (A, T, C, and G in DNA; A, U, C, and G in #RNA), and one is always attached to each of sugars in backbone. The order of the bases along the backbone is what carries genetic information, enabling life as we know it. It’s been hypothesized that, before life evolved, the order of bases along RNA molecules determined the sorts of chemical reactions they could catalyze.
https://arstechnica.com/science/2026/03/we-keep-finding-the-raw-material-of-dna-in-asteroids-whats-it-telling-us/ -
We keep finding the raw material of #DNA in #asteroids—what's it telling us?
There are four #nucleicacids (A, T, C, and G in DNA; A, U, C, and G in #RNA), and one is always attached to each of sugars in backbone. The order of the bases along the backbone is what carries genetic information, enabling life as we know it. It’s been hypothesized that, before life evolved, the order of bases along RNA molecules determined the sorts of chemical reactions they could catalyze.
https://arstechnica.com/science/2026/03/we-keep-finding-the-raw-material-of-dna-in-asteroids-whats-it-telling-us/ -
We keep finding the raw material of #DNA in #asteroids—what's it telling us?
There are four #nucleicacids (A, T, C, and G in DNA; A, U, C, and G in #RNA), and one is always attached to each of sugars in backbone. The order of the bases along the backbone is what carries genetic information, enabling life as we know it. It’s been hypothesized that, before life evolved, the order of bases along RNA molecules determined the sorts of chemical reactions they could catalyze.
https://arstechnica.com/science/2026/03/we-keep-finding-the-raw-material-of-dna-in-asteroids-whats-it-telling-us/ -
We keep finding the raw material of #DNA in #asteroids—what's it telling us?
There are four #nucleicacids (A, T, C, and G in DNA; A, U, C, and G in #RNA), and one is always attached to each of sugars in backbone. The order of the bases along the backbone is what carries genetic information, enabling life as we know it. It’s been hypothesized that, before life evolved, the order of bases along RNA molecules determined the sorts of chemical reactions they could catalyze.
https://arstechnica.com/science/2026/03/we-keep-finding-the-raw-material-of-dna-in-asteroids-whats-it-telling-us/ -
We keep finding the raw material of #DNA in #asteroids—what's it telling us?
There are four #nucleicacids (A, T, C, and G in DNA; A, U, C, and G in #RNA), and one is always attached to each of sugars in backbone. The order of the bases along the backbone is what carries genetic information, enabling life as we know it. It’s been hypothesized that, before life evolved, the order of bases along RNA molecules determined the sorts of chemical reactions they could catalyze.
https://arstechnica.com/science/2026/03/we-keep-finding-the-raw-material-of-dna-in-asteroids-whats-it-telling-us/ -
Our newest publication is out!
We showed that the yeast core factor (CF) binds and specifically recognizes promoter DNA in a two-step process, after which it will recruit RNA Polymerase I, inducing DNA bending and melting to start the transcription process.
https://academic.oup.com/nar/article/54/5/gkag153/8495788
#academicChatter #publication #science #nucleicAcidsResearch #nucleicAcids #yeast #dna #transcription
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Our newest publication is out!
We showed that the yeast core factor (CF) binds and specifically recognizes promoter DNA in a two-step process, after which it will recruit RNA Polymerase I, inducing DNA bending and melting to start the transcription process.
https://academic.oup.com/nar/article/54/5/gkag153/8495788
#academicChatter #publication #science #nucleicAcidsResearch #nucleicAcids #yeast #dna #transcription
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Our newest publication is out!
We showed that the yeast core factor (CF) binds and specifically recognizes promoter DNA in a two-step process, after which it will recruit RNA Polymerase I, inducing DNA bending and melting to start the transcription process.
https://academic.oup.com/nar/article/54/5/gkag153/8495788
#academicChatter #publication #science #nucleicAcidsResearch #nucleicAcids #yeast #dna #transcription
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Our newest publication is out!
We showed that the yeast core factor (CF) binds and specifically recognizes promoter DNA in a two-step process, after which it will recruit RNA Polymerase I, inducing DNA bending and melting to start the transcription process.
https://academic.oup.com/nar/article/54/5/gkag153/8495788
#academicChatter #publication #science #nucleicAcidsResearch #nucleicAcids #yeast #dna #transcription
-
Our newest publication is out!
We showed that the yeast core factor (CF) binds and specifically recognizes promoter DNA in a two-step process, after which it will recruit RNA Polymerase I, inducing DNA bending and melting to start the transcription process.
https://academic.oup.com/nar/article/54/5/gkag153/8495788
#academicChatter #publication #science #nucleicAcidsResearch #nucleicAcids #yeast #dna #transcription
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This structure of a tRNA acceptor-stem mimic demonstrates the use of bromine and phosphorus anomalous scattering for RNA structure determination #Crystallography #AnomalousScattering #NucleicAcids https://doi.org/10.1107/S2053230X26000658
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This structure of a tRNA acceptor-stem mimic demonstrates the use of bromine and phosphorus anomalous scattering for RNA structure determination #Crystallography #AnomalousScattering #NucleicAcids https://doi.org/10.1107/S2053230X26000658
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This structure of a tRNA acceptor-stem mimic demonstrates the use of bromine and phosphorus anomalous scattering for RNA structure determination #Crystallography #AnomalousScattering #NucleicAcids https://doi.org/10.1107/S2053230X26000658
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This structure of a tRNA acceptor-stem mimic demonstrates the use of bromine and phosphorus anomalous scattering for RNA structure determination #Crystallography #AnomalousScattering #NucleicAcids https://doi.org/10.1107/S2053230X26000658
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This structure of a tRNA acceptor-stem mimic demonstrates the use of bromine and phosphorus anomalous scattering for RNA structure determination #Crystallography #AnomalousScattering #NucleicAcids https://doi.org/10.1107/S2053230X26000658
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Very insightful review by the group of Alexander Deiters in @[email protected] They give an overview of the development of covalent #aptamers for protein labeling and inhibition including an overview of the chemistries used. doi.org/10.1039/d5cb... #ChemSky #ChemBio #NucleicAcids #RNA #DNA
Covalent aptamers: agents with... -
Very insightful review by the group of Alexander Deiters in @[email protected] They give an overview of the development of covalent #aptamers for protein labeling and inhibition including an overview of the chemistries used. doi.org/10.1039/d5cb... #ChemSky #ChemBio #NucleicAcids #RNA #DNA
Covalent aptamers: agents with... -
Very insightful review by the group of Alexander Deiters in @[email protected] They give an overview of the development of covalent #aptamers for protein labeling and inhibition including an overview of the chemistries used. doi.org/10.1039/d5cb... #ChemSky #ChemBio #NucleicAcids #RNA #DNA
Covalent aptamers: agents with... -
Very insightful review by the group of Alexander Deiters in RSC Chemical Biology. They give an overview of the development of covalent #aptamers for protein labeling and inhibition including an overview of the chemistries used. https://doi.org/10.1039/d5cb00133a
#Chemistry #ChemBio #NucleicAcids #RNA #DNA -
Very insightful review by the group of Alexander Deiters in RSC Chemical Biology. They give an overview of the development of covalent #aptamers for protein labeling and inhibition including an overview of the chemistries used. https://doi.org/10.1039/d5cb00133a
#Chemistry #ChemBio #NucleicAcids #RNA #DNA -
Very insightful review by the group of Alexander Deiters in RSC Chemical Biology. They give an overview of the development of covalent #aptamers for protein labeling and inhibition including an overview of the chemistries used. https://doi.org/10.1039/d5cb00133a
#Chemistry #ChemBio #NucleicAcids #RNA #DNA -
Very insightful review by the group of Alexander Deiters in RSC Chemical Biology. They give an overview of the development of covalent #aptamers for protein labeling and inhibition including an overview of the chemistries used. https://doi.org/10.1039/d5cb00133a
#Chemistry #ChemBio #NucleicAcids #RNA #DNA -
How did primitive membranes form at the #OriginOfLife and how did they evolve into the cellular envelopes of modern cells?
Exciting talk by Claudia Bonfio about the non-enzymatic formation of phospholipids under conditions that are plausible for early Earth. https://pubs.rsc.org/en/content/articlelanding/2024/sc/d4sc05362a (1/2)
#Chemistry #OriginOfLife #lipid #membrane #evolution #LipidTime #NucleicAcids
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How did primitive membranes form at the #OriginOfLife and how did they evolve into the cellular envelopes of modern cells?
Exciting talk by Claudia Bonfio about the non-enzymatic formation of phospholipids under conditions that are plausible for early Earth. https://pubs.rsc.org/en/content/articlelanding/2024/sc/d4sc05362a (1/2)
#Chemistry #OriginOfLife #lipid #membrane #evolution #LipidTime #NucleicAcids
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How did primitive membranes form at the #OriginOfLife and how did they evolve into the cellular envelopes of modern cells?
Exciting talk by Claudia Bonfio about the non-enzymatic formation of phospholipids under conditions that are plausible for early Earth. https://pubs.rsc.org/en/content/articlelanding/2024/sc/d4sc05362a (1/2)
#Chemistry #OriginOfLife #lipid #membrane #evolution #LipidTime #NucleicAcids
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How did primitive membranes form at the #OriginOfLife and how did they evolve into the cellular envelopes of modern cells?
Exciting talk by Claudia Bonfio about the non-enzymatic formation of phospholipids under conditions that are plausible for early Earth. https://pubs.rsc.org/en/content/articlelanding/2024/sc/d4sc05362a (1/2)
#Chemistry #OriginOfLife #lipid #membrane #evolution #LipidTime #NucleicAcids
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Interesting bioRxiv preprint by the group of Matt Disney. They used fully functionalized fragments to enrich their targets and identify their binding sites on #RNA. Interesting insights into preferential binding to UTRs and the construction of RiboTACs.
https://www.biorxiv.org/content/10.1101/2025.11.05.686775v1
#NucleicAcids #TargetedDegradation #Chemistry #ChemBio -
Interesting bioRxiv preprint by the group of Matt Disney. They used fully functionalized fragments to enrich their targets and identify their binding sites on #RNA. Interesting insights into preferential binding to UTRs and the construction of RiboTACs.
https://www.biorxiv.org/content/10.1101/2025.11.05.686775v1
#NucleicAcids #TargetedDegradation #Chemistry #ChemBio -
Interesting bioRxiv preprint by the group of Matt Disney. They used fully functionalized fragments to enrich their targets and identify their binding sites on #RNA. Interesting insights into preferential binding to UTRs and the construction of RiboTACs.
https://www.biorxiv.org/content/10.1101/2025.11.05.686775v1
#NucleicAcids #TargetedDegradation #Chemistry #ChemBio -
Interesting bioRxiv preprint by the group of Matt Disney. They used fully functionalized fragments to enrich their targets and identify their binding sites on #RNA. Interesting insights into preferential binding to UTRs and the construction of RiboTACs.
https://www.biorxiv.org/content/10.1101/2025.11.05.686775v1
#NucleicAcids #TargetedDegradation #Chemistry #ChemBio -
In the second episode of our new EXplained series, we highlight the #ClusterofExcellence NUCLEATE. At our #university, it is represented by Stefan Engelhardt, who shares insights into #nucleic-acid based #medicine: http://go.tum.de/139582
📷 ProLehre
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In the second episode of our new EXplained series, we highlight the #ClusterofExcellence NUCLEATE. At our #university, it is represented by Stefan Engelhardt, who shares insights into #nucleic-acid based #medicine: http://go.tum.de/139582
📷 ProLehre
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In the second episode of our new EXplained series, we highlight the #ClusterofExcellence NUCLEATE. At our #university, it is represented by Stefan Engelhardt, who shares insights into #nucleic-acid based #medicine: http://go.tum.de/139582
📷 ProLehre
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In the second episode of our new EXplained series, we highlight the #ClusterofExcellence NUCLEATE. At our #university, it is represented by Stefan Engelhardt, who shares insights into #nucleic-acid based #medicine: http://go.tum.de/139582
📷 ProLehre
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In the second episode of our new EXplained series, we highlight the #ClusterofExcellence NUCLEATE. At our #university, it is represented by Stefan Engelhardt, who shares insights into #nucleic-acid based #medicine: http://go.tum.de/139582
📷 ProLehre
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https://www.europesays.com/uk/282910/ Healthy Life: Ancient viruses in our DNA may hold clues to what makes us human | Healthy Life #AnimalHusbandry #biochemistry #Bioinformatics #BiologicalEngineering #BiologicalEvolution #Biology #biotechnology #BranchesOfGenetics #DNA #DnaAnnotation #DNASequencing #DnaVirus #evolution #Gene #Genetics #Genome #HealthSciences #human #HumanGenome #LifeSciences #MolecularBiology #NucleicAcidSequence #NucleicAcids #Science #UK #UnitedKingdom #Virology #Virus
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Read the interview with Stefan Engelhardt, our Professor of #Pharmacology and #Toxicology, who talks about the new #ClusterofExcellence, #NUCLEATE, which explores the function and regulation of #nucleicacids: http://go.tum.de/705241 🧬
📷A. Heddergott
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Read the interview with Stefan Engelhardt, our Professor of #Pharmacology and #Toxicology, who talks about the new #ClusterofExcellence, #NUCLEATE, which explores the function and regulation of #nucleicacids: http://go.tum.de/705241 🧬
📷A. Heddergott
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Read the interview with Stefan Engelhardt, our Professor of #Pharmacology and #Toxicology, who talks about the new #ClusterofExcellence, #NUCLEATE, which explores the function and regulation of #nucleicacids: http://go.tum.de/705241 🧬
📷A. Heddergott
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Read the interview with Stefan Engelhardt, our Professor of #Pharmacology and #Toxicology, who talks about the new #ClusterofExcellence, #NUCLEATE, which explores the function and regulation of #nucleicacids: http://go.tum.de/705241 🧬
📷A. Heddergott
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Read the interview with Stefan Engelhardt, our Professor of #Pharmacology and #Toxicology, who talks about the new #ClusterofExcellence, #NUCLEATE, which explores the function and regulation of #nucleicacids: http://go.tum.de/705241 🧬
📷A. Heddergott