#need2read — Public Fediverse posts

New preprint from Caitlin Mallory / #FosterLab about #HippocampalReplay and its links with the #MedialEntorhinalCortex - looks really cool!!

Self-avoidance dominates the selection of hippocampal replay

#Need2Read #Hippocampus

@beneuroscience #Need2Read (and to look into what the controls are)

@beneuroscience this looks super cool, absolutely #Need2Read!

New #FosterLab preprint, looking very interesting, as usual:
Replay without sharp wave ripples in a spatial memory task

#HippocampalReplay #HippocampalRipples #Hippocampus #SpatialNavigation #Need2Read

@Andrewpapale @adredish oh yes I #Need2Read that one!!

@mrspaghetti @dlevenstein looks pretty cool, thanks for sharing!
#HippocampalReplay #Need2Read

@PhiloNeuroScie looks very interesting - thanks for sharing!!
I wonder how related it is to this recent paper from the #BendorLab: The role of experience in prioritizing hippocampal replay

#HippocampalReplay #Neuroscience #Hippocampus #Need2Read

@adredish These look really interesting! Congrats to all!
#Need2Read

@neuralreckoning @ScholarNexus can’t wait to find the time to read it! And thank you for trying to fix the system!!
#Need2Read

@adredish thanks for the ref! I #Need2Read it…
@neuralreckoning

@anelautrup this looks amazing, congrats!
Do you know if any of the known ‘spatial cells’ types contribute most to these sequences?

#Need2Read

@mattnolan Good points… still, when rats do foraging in 2D, they can have very nice grid cells, but as soon as they move on to 3D, still foraging, the grids break down… 🤔

Roddy (from Grieves et al 2021 says that he’s not aware of any continuous attractor model of grid cells that has been extended to 3D but there should be 2 options: 1) either the grids can integrate movements in the z-axis and that should give rise to columns in 3D, or 2) they can’t and the grid should completely break down in 3D. However, the data showed mostly randomly-located spatial fields that were more spatially-stable than chance, so neither of those 🤔 (similar findings by Ginosar et al., 2021 but for MEC cells that were not necessarily grid cells). But maybe there are now more recent CAN models that we are not aware of!

This reminds me that Gily has a new review paper on the role of #GridCells for #Navigation that I #Need2Read: Ginosar et al., 2023

@andyalexander looking forward to reading this! Congrats!!
#Need2Read

@adredish Thank you so much for the input!
I really #Need2Read that paper. I would actually have expected the rat to be in theta mode while waiting during the delay period, possibly having #TimeCell activity- really interesting that they’re not!

I also see replay / SWRs when rats are anticipating reward, before its delivery, but it is at the goal location while I imagine the delay location in the restaurant row is different from the goal location.

I hope we can discuss all of this at #SFN23!😃

@edeno

Thalamic nucleus reuniens coordinates prefrontal-hippocampal synchrony to suppress extinguished fear

(Me, reading the title:
“suppress extinguished fear”… 🤔
“suppress extinguished fear” 👀
“suppress extinguished fear…?” 🫨 )

Despite the disruption of my mind, this seems really interesting! #Need2Read

#PFC #Hippocampus #NucleusReuniens #Fear #MarenLab

Here’s a really cool-looking paper that I absolutely #Need2Read:

Associative and predictive hippocampal codes support memory-guided behaviors

#Hippocampus #ThetaSequences #HippocamplaReplay #FernandezRuizLab

@marcwhoward Looks super interesting - thanks for sharing! #Need2Read

@PhiloNeuroScie thanks for sharing!
#Need2Read :)

Interesting #NeuroPreprint about separating “motor” and “cognitive” variables in neural analyses, which should really be given more attention in all studies IMO:
Separating cognitive and motor processes in the behaving mouse

by #EconomoLab

#Need2Read

@SteinmetzNeuro super impressive work, and really nice thread! You might want to add some hashtags..

#Need2Read (this one is for me :) )

Another cool #NeuroPreprint (broadly speaking: it’s on #Navigation performance), from #SpiersLab (@hugospiers):
Video gaming, but not reliance on GPS, is associated with spatial navigation performance
I am intrigued by the difference in sample numbers: “n = 822, 280 men, 542 women”? Is that a typo?
And also this:

“There was a significant association between weekly hours of video gaming and navigation performance which was not moderated by gender. After accounting for video game experience, gender was no longer significantly associated with navigation performance.”
Is gender a factor or not? 🤔
#Gaming #Need2Read

Interesting looking new #Hippocampus #NeuroPreprint from #StarkLab:

Local activation of CA1 pyramidal cells induces theta phase precession

“The findings are incompatible with precession models based on inheritance, spreading activation, dual-input, or inhibition-excitation summation. Thus, a precession generator resides locally within CA1”

#PhasePrecession #Optogenetics #Need2Read

Ooh this seems very interesting:
Lost in time: Relocating the perception of duration outside the brain by #RobbeLab (not on here right?)
#Time #TimeEstimation #RatBehaviour #PlaceCells #TimeCells (added those last two because they seem clearly linked to the contents even though I don’t know if they’re actually discussed)

I did a time-estimation experiment and yes, some of the rats did develop these kind of superstitions… like standing at the delay zone… Not all of them though, at least not that we could see! And time cells seem to tell us that they do have some internal representation of time passed… also if time is actually space does it mean that the #TemporalContexModel is actually a MovementContextModel? @marcwhoward you might be interested in this…
#Need2Read

Ooh this seems very interesting:
Lost in time: Relocating the perception of duration outside the brain by #RobbeLab (not on here right?)
#Time #TimeEstimation #RatBehaviour #PlaceCells #TimeCells (added those last two because they seem clearly linked to the contents even though I don’t know if they’re actually discussed)

I did a time-estimation experiment and yes, some of the rats did develop these kind of superstitions… like standing at the delay zone… Not all of them though, at least not that we could see! And time cells seem to tell us that they do have some internal representation of time passed… also if time is actually space does it mean that the #TemporalContexModel is actually a MovementContextModel? @marcwhoward you might be interested in this…
#Need2Read

Ooh this seems very interesting:
Lost in time: Relocating the perception of duration outside the brain by #RobbeLab (not on here right?)
#Time #TimeEstimation #RatBehaviour #PlaceCells #TimeCells (added those last two because they seem clearly linked to the contents even though I don’t know if they’re actually discussed)

I did a time-estimation experiment and yes, some of the rats did develop these kind of superstitions… like standing at the delay zone… Not all of them though, at least not that we could see! And time cells seem to tell us that they do have some internal representation of time passed… also if time is actually space does it mean that the #TemporalContexModel is actually a MovementContextModel? @marcwhoward you might be interested in this…
#Need2Read

Ooh this seems very interesting:
Lost in time: Relocating the perception of duration outside the brain by #RobbeLab (not on here right?)
#Time #TimeEstimation #RatBehaviour #PlaceCells #TimeCells (added those last two because they seem clearly linked to the contents even though I don’t know if they’re actually discussed)

I did a time-estimation experiment and yes, some of the rats did develop these kind of superstitions… like standing at the delay zone… Not all of them though, at least not that we could see! And time cells seem to tell us that they do have some internal representation of time passed… also if time is actually space does it mean that the #TemporalContexModel is actually a MovementContextModel? @marcwhoward you might be interested in this…
#Need2Read

Ooh this seems very interesting:
Lost in time: Relocating the perception of duration outside the brain by #RobbeLab (not on here right?)
#Time #TimeEstimation #RatBehaviour #PlaceCells #TimeCells (added those last two because they seem clearly linked to the contents even though I don’t know if they’re actually discussed)

I did a time-estimation experiment and yes, some of the rats did develop these kind of superstitions… like standing at the delay zone… Not all of them though, at least not that we could see! And time cells seem to tell us that they do have some internal representation of time passed… also if time is actually space does it mean that the #TemporalContexModel is actually a MovementContextModel? @marcwhoward you might be interested in this…
#Need2Read

#NeuroPreprint #DerdickmanLab #PlaceCells #TimeCells #Hippocampus

Time or distance: predictive coding of Hippocampal cells

We show that the type of experiment determined the cells’ encoding, such that in fixed-distance experiments distance-encoding cells dominated, while on fixed-time experiments time-encoding cells dominated.

Seems very interesting! But is it surprising? Place cells are known to encode what is consistent and disregard what is not… 🤔
#Need2Read

Edit: typo

#NeuroPreprint #Hippocampus
Learning produces a hippocampal cognitive map in the form of an orthogonalized state machine

#NeuroMice #CognitiveMap #CalciumImaging #SprustonLab #Modeling (#Need2Read)

#NeuroPreprint #Hippocampus
Learning produces a hippocampal cognitive map in the form of an orthogonalized state machine

#NeuroMice #CognitiveMap #CalciumImaging #SprustonLab #Modeling (#Need2Read)

#NeuroPreprint #Hippocampus
Learning produces a hippocampal cognitive map in the form of an orthogonalized state machine

#NeuroMice #CognitiveMap #CalciumImaging #SprustonLab #Modeling (#Need2Read)

#NeuroPreprint #Hippocampus
Learning produces a hippocampal cognitive map in the form of an orthogonalized state machine

#NeuroMice #CognitiveMap #CalciumImaging #SprustonLab #Modeling (#Need2Read)

#NeuroPreprint #Hippocampus
Learning produces a hippocampal cognitive map in the form of an orthogonalized state machine

#NeuroMice #CognitiveMap #CalciumImaging #SprustonLab #Modeling (#Need2Read)

@PessoaBrain @cogneurophys Ooh how did I miss this? Thanks for sharing!
Would you mind adding hashtags to Hippocampus and Navigation? It really helps for finding posts
I’ll read and come back to discuss! #Need2Read

@AllenNeuroLab Really cool and impressive results! Congrats to all!
#Need2Read

That’s a strange paper… @adredish you might like it:
Using temperature to analyze the neural basis of a time-based decision

#Striatum #Neuroscience #NeuroRat #DecisionMaking #Time #NeuroPaper #Need2Read

That’s a strange paper… @adredish you might like it:
Using temperature to analyze the neural basis of a time-based decision

#Striatum #Neuroscience #NeuroRat #DecisionMaking #Time #NeuroPaper #Need2Read

That’s a strange paper… @adredish you might like it:
Using temperature to analyze the neural basis of a time-based decision

#Striatum #Neuroscience #NeuroRat #DecisionMaking #Time #NeuroPaper #Need2Read

That’s a strange paper… @adredish you might like it:
Using temperature to analyze the neural basis of a time-based decision

#Striatum #Neuroscience #NeuroRat #DecisionMaking #Time #NeuroPaper #Need2Read

That’s a strange paper… @adredish you might like it:
Using temperature to analyze the neural basis of a time-based decision

#Striatum #Neuroscience #NeuroRat #DecisionMaking #Time #NeuroPaper #Need2Read

New preprint on human #Ripples

Hippocampal sharp-wave ripples correlate with naturally occurring self-generated thoughts in humans

Seems very interesting, and a possible good match for what’s happening in rats! #Need2Read!