#sfn23 — Public Fediverse posts

With Clara Sanches at #sfn23 , a #driftdiffusion model analysis of cognitive slowing in aging

Our stellar postdoc Radostina Lyutova presenting her poster on how to improve #motorlearning in #drosophila at #sfn23
Come see her at posterboard UU23 this morning at #sfn #neuroscience

I have presented this poster on #HippocampalReplay at #SFN23 !

I'm also uploading the poster as an image here, and it's on the SFN website: https://cattendee.abstractsonline.com/meeting/10892/presentation/33535

Little summary below:

Our goal was to investigate if replay of hippocampal #PlaceCells was indeed reflecting immediate #SpatialPlanning.

The existing literature is a little unclear: some studies find 'planning replay' and some do not. Most of the time, planning is not dissociated from reward consumption in these studies as they can generally be simplified to an alternation between two rewarded locations. In our case, we separate the location of planning from the location of reward and focus on replay happening at the planning time.

At the location of planning, we find that:

1) there is actually almost no replay at the time of planning
2) the rare 'start replay' events do NOT over-represent the future trajectory, or even the goal
3) the rare 'start replay' events do not differ for successful vs unsuccessful planning.

At the goal location, we find that:

4) Many replays occur at the goal, even before the reward delivery!
5) 'goal replays' strongly over-represent the goal (either before or after reward delivery)
6) 'goal replays' do not over-represent the current trajectory compared to the alternative trajectory, or even the optimal path if the less-optimal path was taken
7) 'goal replays' were strongly affected by errors and were quasi-absent during error trials (choosing an unrewarded end box)

In conclusion:

Reward (received or expected), but not planning, drives hippocampal replay!

Let me know if you have any questions after looking at the poster :D

Edit: updated because this is in the past now (but hoping to publish it soon!)

This is today! If you’re wondering what do #PlaceCells look like on hills then come to this poster to find your answer!
#Hippocampus #SFN23

From: @elduvelle_neuro
https://neuromatch.social/@elduvelle_neuro/111218045785914316

For those at #sfn23 next week, I will be there with my postdoc Clara Sanches, who will be presenting at:

Wednesday 3-4pm PSTR570.16 / VV40

Age related processes impacting processing speed: a diffusion model analysis

We consider effects of age (considered as a continuous variable, rather than comparing separate age cohorts) on drift rate in 3 separate tasks (delay discounting, emotion recognition, and verbal memory), potentially mediated by white matter integrity.

#sfn #DriftDiffusion #AgingResearch

The coolest experiments you’ll see all year in the #PlaceCells #Hippocampus #CognitiveMap field… and I’m not saying this lightly! Congrats to all authors!

Btw they are at #SFN23 in the same session as me (here)! 👀👀👀

From: @PhiloNeuroScie
https://neuromatch.social/@PhiloNeuroScie/111364100508297145

Attending #SfN23 in Washington, DC? Save the date for the US Brain Alliance annual Tools, Tech & Theory social on 11/12 from 6:30-9pm ET. Chat with BRAIN-funded toolmakers about tools & data resources available to the neuroscience community! https://bit.ly/3DF6zkv #studyBRAIN #SfN

@adredish Thank you so much for the input!
I really #Need2Read that paper. I would actually have expected the rat to be in theta mode while waiting during the delay period, possibly having #TimeCell activity- really interesting that they’re not!

I also see replay / SWRs when rats are anticipating reward, before its delivery, but it is at the goal location while I imagine the delay location in the restaurant row is different from the goal location.

I hope we can discuss all of this at #SFN23!😃

@edeno

@debivort @schoppik @markgbaxter @elduvelle_neuro @beneuroscience @jzsimon @jzsimon @jonny

This year, we have two posters for #SFN both in the morning.

On Tuesday, it'll be on optogenetic self-stimulation with Ben deBivort as co-author:

https://www.abstractsonline.com/pp8/#!/10892/presentation/28323

but it'll be mainly the recent work of undergraduate Luisa Guyton.

On Wednesday it'll be on different ways in which we improve #motorlearning in #Drosophila

https://www.abstractsonline.com/pp8/#!/10892/presentation/29876

#sfn23