#metastaar — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #metastaar, aggregated by home.social.
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https://www.nature.com/articles/s41588-022-01225-6 "Powerful, scalable and resource-efficient meta-analysis of #rareVariant associations in large whole genome sequencing studies" #wgs #genetics #genomics #bioinformatics #MetaSTAAR performs rare variant meta-analysis at scale and produces results comparable to using pooled data. We further demonstrate that MetaSTAAR is scalable to biobank-scale cohorts through meta-analysis of #TOPMed WGS data and #UKBiobank WES data of ~200,000 samples.