#medicalpost — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #medicalpost, aggregated by home.social.
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A short news story I wrote reporting on a study that found the shape of your #heart can help predict risk for atrial fibrillation.
The first few paragraphs (most of the story):Rounder hearts predict future heart failure, a-fib
Greater left ventricular sphericity showed 47% greater incidence of #cardiomyopathyMAY 2023 -- Not everyone’s heart is quite the same shape and its shape changes over time – but this could help predict who’s at risk for #cardiomyopathy.
A study in CellPress, where researchers analysed cardiac MRIs of over 30,000 people, found that variations in left ventricle sphericity in normal hearts predicted risk for cardiomyopathy and related outcomes.
Researchers hypothesized that beyond size and function, the shape of hearts might carry extra details about heart health. To study this, they used data from a large biobank with cardiac imaging data to help analyze variation in cardiac morphology in normal populations.
They noted “Cardiomyopathies of different etiologies often result in a similar end-stage phenotype of a more round, spherical ventricle. Among individuals with known cardiac disease, increased sphericity of the left ventricle (LV) has been associated with adverse outcomes, including ventricular arrhythmias and death.”
It also stated that “within the spectrum of normal LV chamber size and systolic function, there exists variation in LV sphericity, and this variation may be a marker of cardiac risk with genetic underpinnings.”
The researchers turned to artificial intelligence to help analyze 38,897 cardiac MRIs from the U.K. Biobank database. The cohort had undergone cardiac MRIs and had normal LV end-diastolic volume, normal LV end-systolic volume, and normal LV ejection fraction.
The team looked at LV sphericity and whether it predicted incident cardiomyopathy as well as clinical manifestations such as atrial fibrillation, heart failure, and #cardiac arrest. Other factors were taken into account such as body mass index, pulse rate, #hypertension, diabetes, and prior #myocardial infarction.
“We found that individuals with spherical hearts were 31% more likely to develop atrial fibrillation and 24% more likely to develop cardiomyopathy,” said Dr. David Ouyang in a press release. He is coauthor of the study and a cardiologist at Cedars Sinai in California....
The full story is online. Sorry, its password protected. It's accessible, free to #doctors and #pharmacists #myocardial #medicine #MedicalPost #MedMastodon #cardiology @medmastodon
MY NEWS REPORT: https://www.canadianhealthcarenetwork.ca/rounder-hearts-predict-future-heart-failure-fib
THE STUDY: https://www.cell.com/action/showPdf?pii=S2666-6340%2823%2900069-7
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One in three #SouthAsians with #ASCVD on statins are eligible for icosapent ethyl (IPE). IPE should be considered for this high-risk population.
Story I wrote for the #MedicalPost. (Sorry, password protected for #doctors and #pharmacists).Highlights:
A third of South Asians in Canada with known atherosclerotic #cardiovascular disease (ASCVD) and who take #statins would qualify to get additional treatment with icosapent ethyl (IPE).This is a significant-sized population who could benefit from the additional lowering of triglycerides using IPE, according to a study presented at the recent annual meeting of the Canadian Cardiovascular Society (#CCS). This year’s CCS had 1,400 in-person delegates, over 350 online delegates and 130 sessions.
However, a major study, the REDUCE-IT trial driving the use of IPE had very few non-white participants, according to a poster abstract presented by Canadian researchers.
IPE is a highly purified preparation of #eicosapentaenoic acid (EPA), which is an omega-3 fatty acid. It is used to treat severe hypertriglyceridemia (500 mg/dL and over). It is used as an adjunct to statin therapy to reduce the risk of cardiovascular events in people whose serum #triglyceride levels are over 150 mg/dL.
#MedMastodon