#led3symposium — Public Fediverse posts

Excited to be part of the @LED3hub and of the organizing committee of the #LED3Lectures and #LED3Symposium. I am convinced that these are amazing initiatives that strengthen our collaborative spirit. New exciting activities are coming in 2026 and 2027.

We are happy that we could continue our activities to bring our researchers closer together including the LED3 PhD/Postdoc Symposium #LED3Symposium and our flagship #LED3Lectures, in which we heard talks by a diverse selection of world-leading speakers in the field of #DrugDiscovery. (2/3)

Congratulations to the winners of the Awards at the #LED3Symposium of the @LED3hub.

I had a blast at the #LED3Symposium. I learned many new things about the exciting and diverse research that is going on in our @LED3hub. A huge thank you to our PhD organizers, Miguel Mata, Inês Justo, Filipe Cruz, Gianluca Turco and Evangelina Geets for making it possible.

As the #LED3Symposium came to an end, we were excited to be able to recognize the most outstanding contributions to the event.
Congratulations to Laurence Cleenewerk (best talk award), Asina Gijasi (best flash talk award) and Thanasis Patsos (best poster award).

The #LED3Symposium was a very successful event with a lot of amazing science and many interdisciplinary interactions.
A huge thanks to our organizers Miguel Mata, Inês Justo, Filipe Cruz, Gianluca Turco, Evangelina Geets, Sebastian Pomplun and @Stephanhacker2.

Interesting talk by Mike Filius at the #LED3Symposium. He talked about his research on an assay using single molecule FRET measured by total internal reflection fluorescence microscopy to characterize aptamer-protein binding kinetics https://www.science.org/doi/10.1126/sciadv.ads9687
#ChemBio #Biochemistry

Amazing talk by Sean McKenna at the #LED3Symposium. He talked about his research on virtual screening (docking, pharmacophore modelling) of large libraries of compounds that can be made combinatorially from in-stock starting materials for rapid hit validation on the example of CCR2.

The second #FlashTalk session at #LED3Symposium was another firework of diverse early #DrugDiscovery topics including β-lactamase evolution (Cristina López Gallego), EC50 determinations (Chenyu Wang), transcription factor inhibitors (Brecht Ellenbroek) and natural products discovery (Pavlo Hrab).

Exciting talk by Max Kloet from the group of Gerbrand van der Heden van Noort from the LUMC at the #LED3Symposium. He talked about his research into the interplay of the posttranslational modifications of ubiquitination and ADP-ribosylation. https://www.biorxiv.org/content/10.1101/2025.05.08.652854v1

#PTMs #ChemBio

Interesting talk by Xuanlin Liu from the groups of Anne-Grete Märtson and Coen van Hasselt at the #LED3Symposium. She talked about her work on characterizing the viral load during Cytomegalovirus (CMV) infections using PCR and TCID50 to build models for efficiency predictions.

Great talk by Mirjam Huizenga from the group of Mario van der Stelt at the #LED3Symposium. She talked about her doctoral research into inhibiting monoacylglycerol lipase (MAGL) for the treatment of chemotherapy-induced peripheral neuropathy. https://www.nature.com/articles/s41467-023-43606-3

Lunch time was also the time for the group photo and the #PosterSession at the #LED3Symposium. Great to see so many people that are excited about early drug discovery coming together and exchanging over the posters. We hope that this sparked many new interdisciplinary ideas and collaborations.

The first #FlashTalk session of the #LED3Symposium gave us insights into early #PKPD modelling for predicting the outcome of clinical studies for #tuberculosis treatment (Asina Gijasi) and into self-encoded libraries for affinity-selection MS of macrocyclic compounds (cycloSELs, Miguel Mata).

Interesting talk by Laurence Cleenewerk from the groups of Joen Luirink and Nathaniel Martin at the #LED3Symposium. She talked about her research on screening natural product extracts for compounds that selectively target components in the cell envelope of Gram-negative bacteria.

Interesting talk by Edith van der Nol from the group of Sebastian Pomplun at the #LED3Symposium. She talked about her doctoral research into barcode-free, self-encoded libraries (SELs) for the discovery of protein binders using affinity-selection MS. https://chemrxiv.org/engage/chemrxiv/article-details/682ee70b3ba0887c3336e338

Great talk by Tessa Gote at the #LED3Symposium on her doctoral research in the Zach Armstrong group. She talked about inhibitors for sialic acid esterases with potential for combating infectious diseases. Exciting insights into #Biochemistry, #Microbiology and #StructuralBiology.

Inspiring keynote lecture by NVBMB Speaker of the Year Jennifer Lippincott-Schwartz at the #LED3Symposium. She talked about studying molecular interactions and dynamics in the cell on the single molecule level using cryo-EM and super-resolution microscopy. https://www.sciencedirect.com/science/article/pii/S1097276524009080?via%3Dihub

The scientific program of the #LED3Symposium gets underway with an inspiring keynote lecture by NVBMB Speaker of the Year Jennifer Lippincott-Schwartz. She talked about her group's exciting contributions to imaging life's structures and their dynamics down to the atomic level.

At the #LED3Symposium, @SeanMcKenna introduced the activities of the Young Scientist Network of the EFMC and their relevance for our LED3 society and overall early career researchers in the field.
Check out their activities here: https://www.efmc.info/ysn

Inês Justo welcomes a full lecture hall to the #LED3Symposium, which was afterwards officially opened by the dean of Faculty of Science of Leiden University, Jasper Knoester. He highlights the importance of interdisciplinary interactions, like fostered by LED3, for world-leading science.
#ChemBio #Chemistry

Very excited for today's #LED3Symposium and looking forward to hearing about all the diverse science that is going on in the @LED3hub directly from the early career researchers.

We are about to get started with the 2nd LED3 PhD/postdoc symposium #LED3Symposium. We are looking forward to a full day of exciting science presented by the early career researchers of our network!
https://www.universiteitleiden.nl/en/science/led3

At the #LED3Symposium, we also announced next year's #LED3Lectures with an amazing program including Emily Balskus, Andrew Leach, Tjeerd Barf, Paola Picotti, Andrea Rentmeister, Jeffery Kelly, John Overington, Kim Lewis, Ed Tate, and Jay Keasling.

We had an amazing day with a lot of exciting, interdisciplinary science at the #LED3Symposium. Over 120 participants took part in our event and learned a lot about early drug discovery projects across the @LED3hub institutes of Leiden University.

Looking forward to the first @LED3hub PhD/postdoc symposium #LED3Symposium on Thursday, June 20th. Very excited to learn about the science done by PhDs and postdocs across our four institutes (Leiden Institute of Chemistry, Leiden Academic Center for Drug Research, Institute of Biology Leiden and Leiden Institute for Advanced Computer Science) at the Faculty of Science of Leiden University.

We are very excited to host the first @LED3hub PhD/postdoc symposium #LED3Symposium on Thursday, June 20th. We are looking forward to keynotes by Marta Artola, Laura Heitman and Nathaniel Martin and especially to many talks and posters by our PhD and postdoc researchers.