#dsrna — Public Fediverse posts

Study reveals how $RNA travels between cells to control #genes across #generations

#dsRNA #SID-1 #sdg-1 #jumpinggenes #epigenetic #C_elegans

https://phys.org/news/2025-02-reveals-rna-cells-genes-generations.html

#Insect #immune insights: Researchers unveil immune system dynamics.

#infection #signalling #Toll_pathway #dsRNA #fitness

https://phys.org/news/2024-04-insect-immune-insights-unveil-dynamics.html

#Insect #immune insights: Researchers unveil immune system dynamics.

#infection #signalling #Toll_pathway #dsRNA #fitness

https://phys.org/news/2024-04-insect-immune-insights-unveil-dynamics.html

#Insect #immune insights: Researchers unveil immune system dynamics.

#infection #signalling #Toll_pathway #dsRNA #fitness

https://phys.org/news/2024-04-insect-immune-insights-unveil-dynamics.html

#Insect #immune insights: Researchers unveil immune system dynamics.

#infection #signalling #Toll_pathway #dsRNA #fitness

https://phys.org/news/2024-04-insect-immune-insights-unveil-dynamics.html

Replicating #chikungunya #virus, which occurs inside a 'spherule', apparently spends 80% of its time in the double-stranded #RNA intermediate state.

From the preprint:

"A first characterization of the filamentous material in the spherule indicated that each spherule contains a single copy of the viral genome, ~80% of which is present in #dsRNA form."
https://www.biorxiv.org/content/10.1101/2022.12.19.521029v1

Science Magazine (@sciencemagazine) First Release: Jean-Laurent Casanova & colleagues report that single-gene recessive inborn errors of OAS–RNase L pathway cause #myeloid cells to produce excess #inflammatory #cytokines following #dsRNA or #SARSCoV2 stimulation. This pathway may drive #MISC, a rare complication of #COVID19 in some #children!

https://bit.ly/Sci_abo3627

2/13
Now #dsRNA, unlike dsDNA, is inherently unstable and the two strands spontaneously separate to allow viral replication to continue.

In fact, they MUST separate for viral replication to continue.