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#contractility — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #contractility, aggregated by home.social.

  1. Replacing external domain of #Ecadherin with DNA binders and giving a kiss of death to another cell to see how strongly they bind!

    ...lovely ! 😃

    #actomyosin #contractility considered too.

  2. CW: Nuclear tension controls mitotic entry by regulating cyclin B1 nuclear translocation

    "[...] a tension-dependent signal on the #nucleus that sets the time for nuclear envelope permeabilization (NEP) and mitotic entry. This signal relies on #actomyosin #contractility, which unfolds the nucleus during the G2-M transition, activating the stretch-sensitive #cPLA2 on the nuclear envelope and regulating the nuclear translocation of #cyclin B1.[...]"
    rupress.org/jcb/article-abstra
    #BioMechanics #MechanoBiology #NuclearTension #CellBiology #CellCycle #CellDivision #NuclearEnvelope #NuclearTranslocation #CellCompression #GenomicInstability

  3. CW: Nuclear tension controls mitotic entry by regulating cyclin B1 nuclear translocation

    "[...] a tension-dependent signal on the #nucleus that sets the time for nuclear envelope permeabilization (NEP) and mitotic entry. This signal relies on #actomyosin #contractility, which unfolds the nucleus during the G2-M transition, activating the stretch-sensitive #cPLA2 on the nuclear envelope and regulating the nuclear translocation of #cyclin B1.[...]"
    rupress.org/jcb/article-abstra
    #BioMechanics #MechanoBiology #NuclearTension #CellBiology #CellCycle #CellDivision #NuclearEnvelope #NuclearTranslocation #CellCompression #GenomicInstability

  4. CW: Nuclear tension controls mitotic entry by regulating cyclin B1 nuclear translocation

    "[...] a tension-dependent signal on the #nucleus that sets the time for nuclear envelope permeabilization (NEP) and mitotic entry. This signal relies on #actomyosin #contractility, which unfolds the nucleus during the G2-M transition, activating the stretch-sensitive #cPLA2 on the nuclear envelope and regulating the nuclear translocation of #cyclin B1.[...]"
    rupress.org/jcb/article-abstra
    #BioMechanics #MechanoBiology #NuclearTension #CellBiology #CellCycle #CellDivision #NuclearEnvelope #NuclearTranslocation #CellCompression #GenomicInstability