#vigibase — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #vigibase, aggregated by home.social.
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Check out our recent paper on #vascular cell apoptotic vulnerabilities to #cancer therapeutics, including #radiotherapy, #chemotherapy and targeted agents (e.g. #proteasome inhibitors, #BH3mimetics). We find that #EndothelialCells remain primed for #apoptosis throughout development into adulthood and may represent a “weakest link” vulnerability in multiple tissues for development of toxicities. https://www.science.org/doi/full/10.1126/sciadv.abn6579
#Celldeath #CardioOncology #VigiBase #RadioBiology #BH3Profiling