#prdm9 — Public Fediverse posts

PRDM9 helps determine the location of recombination hotspots in many mammals. Study of salmonid fish reveals that #PRDM9 function is conserved across vertebrates, and this peculiar evolutionary runaway caused by PRDM9 has been active for 100s of millions of years #plosbiology plos.io/3DIvFCG

I am very pleased to share with the mastodon community the first part of my PhD work:

High prevalence of Prdm9-independent recombination hotspots in placental #mammals

https://www.biorxiv.org/content/10.1101/2023.11.17.567540v1

This work was done in collaboration with @djivanprentout Alexandre Laverré, Théo Tricou and @duret_lbbe. (1/8)

#Recombination #PopGen #Evolution #gBGC #PRDM9

#introduction
I'm a PhD student based in Lyon (France) with broad interests in molecular evolution.
My three main axes of research are 1) fitness landscapes, DFE estimation and adaptation, 2) GC-biased gene conversion, mutational biases and genetic load, and 3) recombination landscapes and the evolution of the protein PRDM9.

#Selection #Adaptation #gBGC #Recombination #PRDM9