#placecell — Public Fediverse posts

@elduvelle_neuro @Andrewpapale
@BrianMSweis

#CrossSpecies #neuroscience

As Andy Papale said, we have a bunch of papers with both rats and mice on the #RestaurantRow task. (The data is all in https://www.nature.com/articles/s42003-022-04235-6, and publicly available.) Generally, we talk about similarities, but mice learn slower. Rats show the transition from wait zone to #precommitment in the offer zone in a few days, while mice take a lot longer.

Another space where I think there have been rat and mouse comparisons (although I don't find any explicit comparisons) is in the place field stability literature. My memory is that Cliff Kentros had really cool data on (#PlaceCell) #PlaceField stability as a function of #hippocampus #dopamine levels and task. (https://www.nature.com/articles/s42003-022-04235-6) Rats tended to live on the high-DA (place cells are stable) side while mice tended to live on the low-DA (place cells are unstable) side. But both could be manipulated with tasks and #dopamine (ant)agonists. I don't know if anyone explicitly looked at this.

@elduvelle_neuro @Andrewpapale
@BrianMSweis

#CrossSpecies #neuroscience

As Andy Papale said, we have a bunch of papers with both rats and mice on the #RestaurantRow task. (The data is all in https://www.nature.com/articles/s42003-022-04235-6, and publicly available.) Generally, we talk about similarities, but mice learn slower. Rats show the transition from wait zone to #precommitment in the offer zone in a few days, while mice take a lot longer.

Another space where I think there have been rat and mouse comparisons (although I don't find any explicit comparisons) is in the place field stability literature. My memory is that Cliff Kentros had really cool data on (#PlaceCell) #PlaceField stability as a function of #hippocampus #dopamine levels and task. (https://www.nature.com/articles/s42003-022-04235-6) Rats tended to live on the high-DA (place cells are stable) side while mice tended to live on the low-DA (place cells are unstable) side. But both could be manipulated with tasks and #dopamine (ant)agonists. I don't know if anyone explicitly looked at this.

@elduvelle_neuro @Andrewpapale
@BrianMSweis

#CrossSpecies #neuroscience

As Andy Papale said, we have a bunch of papers with both rats and mice on the #RestaurantRow task. (The data is all in https://www.nature.com/articles/s42003-022-04235-6, and publicly available.) Generally, we talk about similarities, but mice learn slower. Rats show the transition from wait zone to #precommitment in the offer zone in a few days, while mice take a lot longer.

Another space where I think there have been rat and mouse comparisons (although I don't find any explicit comparisons) is in the place field stability literature. My memory is that Cliff Kentros had really cool data on (#PlaceCell) #PlaceField stability as a function of #hippocampus #dopamine levels and task. (https://www.nature.com/articles/s42003-022-04235-6) Rats tended to live on the high-DA (place cells are stable) side while mice tended to live on the low-DA (place cells are unstable) side. But both could be manipulated with tasks and #dopamine (ant)agonists. I don't know if anyone explicitly looked at this.

@elduvelle_neuro @Andrewpapale
@BrianMSweis

#CrossSpecies #neuroscience

As Andy Papale said, we have a bunch of papers with both rats and mice on the #RestaurantRow task. (The data is all in https://www.nature.com/articles/s42003-022-04235-6, and publicly available.) Generally, we talk about similarities, but mice learn slower. Rats show the transition from wait zone to #precommitment in the offer zone in a few days, while mice take a lot longer.

Another space where I think there have been rat and mouse comparisons (although I don't find any explicit comparisons) is in the place field stability literature. My memory is that Cliff Kentros had really cool data on (#PlaceCell) #PlaceField stability as a function of #hippocampus #dopamine levels and task. (https://www.nature.com/articles/s42003-022-04235-6) Rats tended to live on the high-DA (place cells are stable) side while mice tended to live on the low-DA (place cells are unstable) side. But both could be manipulated with tasks and #dopamine (ant)agonists. I don't know if anyone explicitly looked at this.

@elduvelle_neuro @Andrewpapale
@BrianMSweis

#CrossSpecies #neuroscience

As Andy Papale said, we have a bunch of papers with both rats and mice on the #RestaurantRow task. (The data is all in https://www.nature.com/articles/s42003-022-04235-6, and publicly available.) Generally, we talk about similarities, but mice learn slower. Rats show the transition from wait zone to #precommitment in the offer zone in a few days, while mice take a lot longer.

Another space where I think there have been rat and mouse comparisons (although I don't find any explicit comparisons) is in the place field stability literature. My memory is that Cliff Kentros had really cool data on (#PlaceCell) #PlaceField stability as a function of #hippocampus #dopamine levels and task. (https://www.nature.com/articles/s42003-022-04235-6) Rats tended to live on the high-DA (place cells are stable) side while mice tended to live on the low-DA (place cells are unstable) side. But both could be manipulated with tasks and #dopamine (ant)agonists. I don't know if anyone explicitly looked at this.

Please welcome the great @aheadofthenerve to Mastodon / the Fediverse! So nice to have another #PlaceCell #Neuroscientist on here 😁 (and also a #CalciumImaging expert)!

#Hippocampus #NeuroRats

From: @aheadofthenerve
https://neuromatch.social/@aheadofthenerve/111767478048631695

6 - A thread of part II of our #4Room #PlaceCell paper, explaining how they create different representations for each of our 4 geometrically-identical rooms:
https://elduvelle.github.io/ElDuvelle/status/1319674602658746369/

Same paper as this post

This was a little surprising because many studies show that identical geometry is usually sufficient to generate very similar place cell maps (e.g . Place field repetition and spatial learning in a multicompartment environment)
The differences could be due to the different directional signal when entering each different room...

6/x

6 - A thread of part II of our #4Room #PlaceCell paper, explaining how they create different representations for each of our 4 geometrically-identical rooms:
https://elduvelle.github.io/ElDuvelle/status/1319674602658746369/

Same paper as this post

This was a little surprising because many studies show that identical geometry is usually sufficient to generate very similar place cell maps (e.g . Place field repetition and spatial learning in a multicompartment environment)
The differences could be due to the different directional signal when entering each different room...

6/x

6 - A thread of part II of our #4Room #PlaceCell paper, explaining how they create different representations for each of our 4 geometrically-identical rooms:
https://elduvelle.github.io/ElDuvelle/status/1319674602658746369/

Same paper as this post

This was a little surprising because many studies show that identical geometry is usually sufficient to generate very similar place cell maps (e.g . Place field repetition and spatial learning in a multicompartment environment)
The differences could be due to the different directional signal when entering each different room...

6/x

6 - A thread of part II of our #4Room #PlaceCell paper, explaining how they create different representations for each of our 4 geometrically-identical rooms:
https://elduvelle.github.io/ElDuvelle/status/1319674602658746369/

Same paper as this post

This was a little surprising because many studies show that identical geometry is usually sufficient to generate very similar place cell maps (e.g . Place field repetition and spatial learning in a multicompartment environment)
The differences could be due to the different directional signal when entering each different room...

6/x

6 - A thread of part II of our #4Room #PlaceCell paper, explaining how they create different representations for each of our 4 geometrically-identical rooms:
https://elduvelle.github.io/ElDuvelle/status/1319674602658746369/

Same paper as this post

This was a little surprising because many studies show that identical geometry is usually sufficient to generate very similar place cell maps (e.g . Place field repetition and spatial learning in a multicompartment environment)
The differences could be due to the different directional signal when entering each different room...

6/x

Here are a few of my favourites from my twitter-detached archive :

1- Types of #PlaceCell papers...

https://elduvelle.github.io/ElDuvelle/status/1388075267453857792/

#Neuroscience #Neuroscientist #Hippocampus #NeuroPapers

1/x

Here are a few of my favourites from my twitter-detached archive :

1- Types of #PlaceCell papers...

https://elduvelle.github.io/ElDuvelle/status/1388075267453857792/

#Neuroscience #Neuroscientist #Hippocampus #NeuroPapers

1/x

I guess it's time to finelly do my #introduction !
I'm a PhD student in Michaël Zugaro's lab
I'm studying the interaction between spatial coding in the #hippocampus and reward representation by #dopamine signaling, especially the VTA - Nucleus Accumbens pathway.
Doing ephys extra-cellular recordings in freely mooving rats trying to catch some chocolate milk!
The dying bird convinced me that mastodon was the way to go and I'm glad to see the neuroscience community growing!

I'm a bit shy on social media but I'll boost everything related to the brain that I find interesting 🧠​
#PlaceCell #neuroscience #reward

Very early sneak peek on what I'm currently working on... Yes it's #PlaceCell #Replay !!

#Hippocampus #Hexamaze

fun #PaperQuote, from the methods of a #PlaceCell paper:

[…] small white Christmas tree lights, centered 160 cm over the
cylinder floor, provided the only illumination in the black room. These conditions provided very little directional information other than the cue card; even the experimenters at times became disoriented after some time in the room, opening the curtain at the wrong location at the end of the session when trying to find the door.

… ooops 😂
The paper: Knierim et al., 1995

(discovered by Roddy Grieves, not on Mastodon)

Here are some #PlaceCell clusters for you (#Tetrode recordings) 😃​
#Hippocampus