#orf8 — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #orf8, aggregated by home.social.
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#Virological characteristics of the #SARS-CoV-2 #Omicron #XBB15 #variant, Nat Commun.: https://www.nature.com/articles/s41467-024-45274-3
-- We provide intrinsic pathogenicity of XBB.1 & XBB.1.5 in hamsters. ...we find that #ORF8 nonsense mutation of XBB.1.5 resulted in impairment of #MHC suppression. In vivo experiments using recombinant viruses reveal that XBB.1.5 mutations are involved with reduced virulence of XBB.1.5... our study identifies 2 viral functions defined difference between XBB.1 & XBB.1.5.