#cas12a — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #cas12a, aggregated by home.social.
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Existing #Cas12a nucleases are too large for #AAV-based #GeneTherapy. @grimmlab explores a #PLOSBiology study of a new Cas12a variant, compatible with in vivo #GenomeEditing via all-in-one AAV delivery. Paper: https://plos.io/3UWqpjC Primer: https://plos.io/4fmjk5F
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This study characterizes a novel compact #Cas12a (EbCas12a) from an uncultured Erysipelotrichia #bacterium and develops an all-in-one #CRISPR delivery system whereby this EbCas12a can be packaged with its crRNA into a single AAV vector #PLOSBiology https://plos.io/3UWqpjC