#cas12a — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #cas12a, aggregated by home.social.
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Existing #Cas12a nucleases are too large for #AAV-based #GeneTherapy. @grimmlab explores a #PLOSBiology study of a new Cas12a variant, compatible with in vivo #GenomeEditing via all-in-one AAV delivery. Paper: https://plos.io/3UWqpjC Primer: https://plos.io/4fmjk5F
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Existing #Cas12a nucleases are too large for #AAV-based #GeneTherapy. @grimmlab explores a #PLOSBiology study of a new Cas12a variant, compatible with in vivo #GenomeEditing via all-in-one AAV delivery. Paper: https://plos.io/3UWqpjC Primer: https://plos.io/4fmjk5F
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Existing #Cas12a nucleases are too large for #AAV-based #GeneTherapy. @grimmlab explores a #PLOSBiology study of a new Cas12a variant, compatible with in vivo #GenomeEditing via all-in-one AAV delivery. Paper: https://plos.io/3UWqpjC Primer: https://plos.io/4fmjk5F
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Existing #Cas12a nucleases are too large for #AAV-based #GeneTherapy. @grimmlab explores a #PLOSBiology study of a new Cas12a variant, compatible with in vivo #GenomeEditing via all-in-one AAV delivery. Paper: https://plos.io/3UWqpjC Primer: https://plos.io/4fmjk5F
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Existing #Cas12a nucleases are too large for #AAV-based #GeneTherapy. @grimmlab explores a #PLOSBiology study of a new Cas12a variant, compatible with in vivo #GenomeEditing via all-in-one AAV delivery. Paper: https://plos.io/3UWqpjC Primer: https://plos.io/4fmjk5F
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This study characterizes a novel compact #Cas12a (EbCas12a) from an uncultured Erysipelotrichia #bacterium and develops an all-in-one #CRISPR delivery system whereby this EbCas12a can be packaged with its crRNA into a single AAV vector #PLOSBiology https://plos.io/3UWqpjC
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This study characterizes a novel compact #Cas12a (EbCas12a) from an uncultured Erysipelotrichia #bacterium and develops an all-in-one #CRISPR delivery system whereby this EbCas12a can be packaged with its crRNA into a single AAV vector #PLOSBiology https://plos.io/3UWqpjC
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This study characterizes a novel compact #Cas12a (EbCas12a) from an uncultured Erysipelotrichia #bacterium and develops an all-in-one #CRISPR delivery system whereby this EbCas12a can be packaged with its crRNA into a single AAV vector #PLOSBiology https://plos.io/3UWqpjC
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This study characterizes a novel compact #Cas12a (EbCas12a) from an uncultured Erysipelotrichia #bacterium and develops an all-in-one #CRISPR delivery system whereby this EbCas12a can be packaged with its crRNA into a single AAV vector #PLOSBiology https://plos.io/3UWqpjC
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This study characterizes a novel compact #Cas12a (EbCas12a) from an uncultured Erysipelotrichia #bacterium and develops an all-in-one #CRISPR delivery system whereby this EbCas12a can be packaged with its crRNA into a single AAV vector #PLOSBiology https://plos.io/3UWqpjC
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Researchers develop prime editors using #Cas12a and #circular_RNAs in human #cells.
https://phys.org/news/2024-01-prime-editors-cas12a-circular-rnas.html
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Researchers develop prime editors using #Cas12a and #circular_RNAs in human #cells.
https://phys.org/news/2024-01-prime-editors-cas12a-circular-rnas.html
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Researchers develop prime editors using #Cas12a and #circular_RNAs in human #cells.
https://phys.org/news/2024-01-prime-editors-cas12a-circular-rnas.html
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Researchers develop prime editors using #Cas12a and #circular_RNAs in human #cells.
https://phys.org/news/2024-01-prime-editors-cas12a-circular-rnas.html
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Researchers develop prime editors using #Cas12a and #circular_RNAs in human #cells.
https://phys.org/news/2024-01-prime-editors-cas12a-circular-rnas.html
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Dynamic #CRISPR: structures of apo Cas12a, Cas12a-crRNA & Cas12a-crRNA-DNA reveal #Cas12a's unique elongated form, its mechanism of #crRNA binding & the conformational dynamics required to target its substrate DNA for cleavage #PLOSBiology https://plos.io/3ZNcpKr
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Dynamic #CRISPR: structures of apo Cas12a, Cas12a-crRNA & Cas12a-crRNA-DNA reveal #Cas12a's unique elongated form, its mechanism of #crRNA binding & the conformational dynamics required to target its substrate DNA for cleavage #PLOSBiology https://plos.io/3ZNcpKr
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Dynamic #CRISPR: structures of apo Cas12a, Cas12a-crRNA & Cas12a-crRNA-DNA reveal #Cas12a's unique elongated form, its mechanism of #crRNA binding & the conformational dynamics required to target its substrate DNA for cleavage #PLOSBiology https://plos.io/3ZNcpKr
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Dynamic #CRISPR: structures of apo Cas12a, Cas12a-crRNA & Cas12a-crRNA-DNA reveal #Cas12a's unique elongated form, its mechanism of #crRNA binding & the conformational dynamics required to target its substrate DNA for cleavage #PLOSBiology https://plos.io/3ZNcpKr
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Dynamic #CRISPR: structures of apo Cas12a, Cas12a-crRNA & Cas12a-crRNA-DNA reveal #Cas12a's unique elongated form, its mechanism of #crRNA binding & the conformational dynamics required to target its substrate DNA for cleavage #PLOSBiology https://plos.io/3ZNcpKr
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Dynamic #CRISPR: structures of apo Cas12a, Cas12a-crRNA & Cas12a-crRNA-DNA reveal #Cas12a's unique elongated form, its mechanism of #crRNA binding & the conformational dynamics required to target its substrate DNA for cleavage #PLOSBiology https://plos.io/3ZNcpKr
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Dynamic #CRISPR: structures of apo Cas12a, Cas12a-crRNA & Cas12a-crRNA-DNA reveal #Cas12a's unique elongated form, its mechanism of #crRNA binding & the conformational dynamics required to target its substrate DNA for cleavage #PLOSBiology https://plos.io/3ZNcpKr
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Dynamic #CRISPR: structures of apo Cas12a, Cas12a-crRNA & Cas12a-crRNA-DNA reveal #Cas12a's unique elongated form, its mechanism of #crRNA binding & the conformational dynamics required to target its substrate DNA for cleavage #PLOSBiology https://plos.io/3ZNcpKr
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Dynamic #CRISPR: structures of apo Cas12a, Cas12a-crRNA & Cas12a-crRNA-DNA reveal #Cas12a's unique elongated form, its mechanism of #crRNA binding & the conformational dynamics required to target its substrate DNA for cleavage #PLOSBiology https://plos.io/3ZNcpKr
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Dynamic #CRISPR: structures of apo Cas12a, Cas12a-crRNA & Cas12a-crRNA-DNA reveal #Cas12a's unique elongated form, its mechanism of #crRNA binding & the conformational dynamics required to target its substrate DNA for cleavage #PLOSBiology https://plos.io/3ZNcpKr
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Dynamic #CRISPR: structures of apo Cas12a, Cas12a-crRNA & Cas12a-crRNA-DNA reveal #Cas12a's unique elongated form, its mechanism of #crRNA binding & the conformational dynamics required to target its substrate DNA for cleavage #PLOSBiology https://plos.io/3ZNcpKr
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Dynamic #CRISPR: structures of apo Cas12a, Cas12a-crRNA & Cas12a-crRNA-DNA reveal #Cas12a's unique elongated form, its mechanism of #crRNA binding & the conformational dynamics required to target its substrate DNA for cleavage #PLOSBiology https://plos.io/3ZNcpKr
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Dynamic #CRISPR: structures of apo Cas12a, Cas12a-crRNA & Cas12a-crRNA-DNA reveal #Cas12a's unique elongated form, its mechanism of #crRNA binding & the conformational dynamics required to target its substrate DNA for cleavage #PLOSBiology https://plos.io/3ZNcpKr
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Dynamic #CRISPR: structures of apo Cas12a, Cas12a-crRNA & Cas12a-crRNA-DNA reveal #Cas12a's unique elongated form, its mechanism of #crRNA binding & the conformational dynamics required to target its substrate DNA for cleavage #PLOSBiology https://plos.io/3ZNcpKr
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Dynamic #CRISPR: structures of apo Cas12a, Cas12a-crRNA & Cas12a-crRNA-DNA reveal #Cas12a's unique elongated form, its mechanism of #crRNA binding & the conformational dynamics required to target its substrate DNA for cleavage #PLOSBiology https://plos.io/3ZNcpKr