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#aav — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #aav, aggregated by home.social.

  1. Myocardial infarction (MI) boosts cardiac AAV transduction.

    🧬 Increased AAV gene delivery post-MI.
    ⏳ Peak at day 3 post-MI.
    ♻️ Independent of AAV dosage/serotypes.
    🔬 Harnessing MI boosts gene therapy for heart conditions.

    #MyocardialInfarction #GeneTherapy #AAV #CardiovascularResearch #Pub2Post

    tnyp.me/VJ61sNPM/m

  2. Bus- und Bahnfahrer müssen 2025 tiefer in die Tasche greifen: Drei NRW-Verkehrsverbünde ziehen zum 1. Januar die Ticketpreise an.#VRR #VRS #WT #AAV #Verkehrsverbund #Preise #ÄnderungenJanuar2025
    ÖPNV-Tickets: So viel mehr kosten Bus und Bahn ab 2025
  3. Bus- und Bahnfahrer müssen 2025 tiefer in die Tasche greifen: Drei NRW-Verkehrsverbünde ziehen zum 1. Januar die Ticketpreise an.#VRR #VRS #WT #AAV #Verkehrsverbund #Preise #ÄnderungenJanuar2025
    ÖPNV-Tickets: So viel mehr kosten Bus und Bahn ab 2025
  4. Bus- und Bahnfahrer müssen 2025 tiefer in die Tasche greifen: Drei NRW-Verkehrsverbünde ziehen zum 1. Januar die Ticketpreise an.#VRR #VRS #WT #AAV #Verkehrsverbund #Preise #ÄnderungenJanuar2025
    ÖPNV-Tickets: So viel mehr kosten Bus und Bahn ab 2025
  5. I always love learning about new plasmid technologies (maybe I am biased from my Addgene days). Researchers from the University of Rochester developed a dual AAV vector system called StitchR that can deliver plasmids containing gene fragments that can be subsequently cut out and assembled into a functional gene. This helps overcome the small packaging capacity of AAVs.

    Find out more from Drug Discovery News : buff.ly/4hwaxPb

    #AAV #GeneTherapy

  6. Enfermedades virales y fertilidad, revisión sobre el efecto en la calidad seminal. Muchas de ellas tienen un efecto negativo, especialmente adenovirus, hepatitis B y papiloma. https://buff.ly/3ZyjUay #bianorbiotech #MaleInfertility #HPV #AAV #HBV

    buff.ly/3ZyjUay

  7. What #AAV dose will be needed for optogenetic brain implants aimed at restoring vision in humans? thetransmitter.org/spectrum/wh What's next for brain-directed gene therapy after death in Neurogene trial.

  8. Existing #Cas12a nucleases are too large for #AAV-based #GeneTherapy. @grimmlab explores a #PLOSBiology study of a new Cas12a variant, compatible with in vivo #GenomeEditing via all-in-one AAV delivery. Paper: plos.io/3UWqpjC Primer: plos.io/4fmjk5F

  9. Q for my fellow neuroscience peeps. Is there a way to stabilize the expression of cre if its under the control of a promoter that is active only transiently during development?

    Is it possible to cross a cre line with a cre-dependent cre-expressing reporter mouse so that cre become permanently expressed in the population of interest, and amenable for e.g. virus injection in the adult?

    Are there tried and true solutions?

    #AAV #cre #MouseModels #neuroscience

  10. thinking about making a set of dlx creOFF AAV constructs a la @JDimidschstein and @sohallab. before i do - has anyone got a stash? initially gfp / chr2 but also likely switch gfp/dtomato too. for some 'NOT x' experiments. would be nice if they already existed! #neuroscience #neuromethods #aav #mouse #interneurons HT @elduvelle for the hashtags!

  11. Gene Therapy Reverses Age-Related Hearing Loss in Mice

    The efficacy of adeno-associated virus (AAV) vectors in reversing genetic hearing loss in aged animal models has been demonstrated.

    #Biomedicine #GeneTherapy #ViralVector #AAV #HearingLoss #AuditoryNeuroscience #Neuroscience

    neurosciencenews.com/gene-ther

  12. Someone did an angry voice bot

    @angry_voice

    #AAV #AnotherAngryVoice

    It's something I suppose, but I'd rather have his Facebook posts crossposted here.