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#arthritis — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #arthritis, aggregated by home.social.

  1. I think pre-emptive dosing myself with co-codamol before the arthritis hits my fingers is working. I've only had to use the splints for relief once this week so far.
    The GP has increased the co-codamol strength so hopefully even that'll improve.

    #arthritis #arthralgia #finasteride

  2. I think pre-emptive dosing myself with co-codamol before the arthritis hits my fingers is working. I've only had to use the splints for relief once this week so far.
    The GP has increased the co-codamol strength so hopefully even that'll improve.

    #arthritis #arthralgia #finasteride

  3. I think pre-emptive dosing myself with co-codamol before the arthritis hits my fingers is working. I've only had to use the splints for relief once this week so far.
    The GP has increased the co-codamol strength so hopefully even that'll improve.

    #arthritis #arthralgia #finasteride

  4. I think pre-emptive dosing myself with co-codamol before the arthritis hits my fingers is working. I've only had to use the splints for relief once this week so far.
    The GP has increased the co-codamol strength so hopefully even that'll improve.

    #arthritis #arthralgia #finasteride

  5. I think pre-emptive dosing myself with co-codamol before the arthritis hits my fingers is working. I've only had to use the splints for relief once this week so far.
    The GP has increased the co-codamol strength so hopefully even that'll improve.

    #arthritis #arthralgia #finasteride

  6. I've had three extremely useful conversations with two different pharmacists today.

    The Omeprazole I was prescribed after my last gastroscopy is causing severe pains in my arthritic fingers (despite the hospital consultant saying it wouldn't). Pharmacist has confirmed it's a rare, but documented, side effect of •all• PPIs.

    The pharmacist at the GP surgery has arranged for me to get an 8 week prescription of Famotdine instead, and to review it when I'm back from holiday.

    #PPI #NHS #Medication #Arthritis #GORD #GERD

  7. 🚨BREAKING: Scientists "cure" #arthritis with ✨magic✨ #cartilage regrowth—meanwhile, knee replacement surgeons are updating their resumes. 🙄🔬 Probably only a millennium too late for the #dinosaurs though. 🦖
    sciencedaily.com/releases/2026 #breakingnews #cure #regrowth #kneehealth #HackerNews #ngated

  8. While my arthritis has eased off significantly since I stopped taking the Lanzaprazole, I'm still getting pain in my thumbs particularly in the evenings.
    So I'm back to wearing the thumb splint which helps a lot.
    At least the knee & hip pains have gone.

    I had quite bad back pain in the night which I think might be the pain that Lansaprazole was given in the first place.

    I'd rather have the stomach and back pain than the arthritis pains.

    I've got a phone consultation with the GP surgery but it's in about 10 days time.

    #arthritis #gerd #gord #Lansaprazole #osteoarthritis #PPI

  9. Curcumin: The Natural Powerhouse for Health and Wellness

    When you hear about turmeric, the golden spice that has been a staple in Indian kitchens for centuries, you might think of its vibrant color and strong flavor. But beneath this common spice lies a hidden gem that holds immense health benefits—curcumin. This powerful compound is the primary active ingredient in turmeric and is responsible for most of its health-boosting properties. Despite its incredible potential, many people still aren’t familiar with curcumin and how it can transform their well-being.

    I remember when I first stumbled upon curcumin during my own health journey. I had been struggling with persistent joint pain and inflammation, and despite trying various remedies, nothing seemed to work. It was then that I came across curcumin and decided to give it a shot. To my surprise, incorporating it into my routine made a significant difference in reducing my pain.

    What Is Curcumin?

    Curcumin is a bright yellow compound found in the roots of the turmeric plant (Curcuma longa). While turmeric itself has been widely used for its medicinal properties, it’s the curcumin within that delivers the most significant health benefits. Curcumin is a polyphenol, which means it’s rich in antioxidants that protect the body from damage and inflammation.

    The catch? Turmeric only contains about 3-5% curcumin, so you would need to consume a significant amount of turmeric to achieve its full effects. Thankfully, curcumin supplements are now available, offering a concentrated dose of this powerful compound.

    Health Benefits of Curcumin

    Curcumin’s potential health benefits are vast, and research is constantly uncovering more ways it can improve your health. Here are some of the most compelling reasons to add curcumin to your wellness routine:

    1. Potent Anti-Inflammatory Properties

    One of the most well-known benefits of curcumin is its ability to fight chronic inflammation. Inflammation is your body’s natural response to injury or infection, but when it becomes chronic, it can lead to diseases like heart disease, arthritis, and even cancer. Curcumin works by blocking molecules like NF-kB, which trigger inflammation in the body. Studies have shown that curcumin can be just as effective as some anti-inflammatory drugs, without the harmful side effects.

    2. Rich in Antioxidants

    Curcumin is a powerful antioxidant, which means it helps neutralize free radicals—unstable molecules that can damage your cells and contribute to aging and diseases. Not only does curcumin scavenge free radicals, but it also boosts your body’s own production of antioxidant enzymes, creating a double-layer of protection.

    3. Supports Brain Health

    Curcumin has been shown to cross the blood-brain barrier, which allows it to have direct effects on the brain. It helps increase levels of brain-derived neurotrophic factor (BDNF), a type of growth hormone that helps brain cells survive and multiply. Low levels of BDNF have been linked to conditions like depression and Alzheimer’s disease. By boosting BDNF, curcumin may help delay or even reverse brain-related diseases and cognitive decline.

    4. Boosts Heart Health

    Heart disease is one of the leading causes of death worldwide, and curcumin can play a vital role in preventing it. It improves the function of the endothelium, which is the lining of your blood vessels. Poor endothelial function is a major factor in heart disease. Curcumin’s anti-inflammatory and antioxidant properties also support heart health by reducing the risk of plaque buildup in the arteries.

    5. May Help Prevent and Treat Cancer

    Curcumin has been studied for its potential role in fighting cancer. Its ability to reduce inflammation, neutralize free radicals, and inhibit the growth of cancerous cells makes it a promising supplement in both cancer prevention and treatment. While more research is needed, some studies suggest curcumin may help slow the spread of cancer and make chemotherapy more effective.

    6. Improves Joint Health

    If you suffer from joint pain or arthritis, curcumin could provide relief. Its anti-inflammatory effects make it highly effective in reducing the pain and stiffness associated with arthritis, particularly rheumatoid arthritis and osteoarthritis. Many people find that taking curcumin supplements helps them manage chronic pain without relying on prescription medications.

    How to Incorporate Curcumin Into Your Routine

    With so many potential benefits, you might be wondering how to get more curcumin into your daily life. Here are a few simple ways to do it:

    1. Curcumin Supplements: Since turmeric contains only a small amount of curcumin, supplements are the easiest and most efficient way to get a therapeutic dose. Look for curcumin supplements that contain black pepper extract (piperine), as it significantly enhances curcumin absorption by up to 2,000%.
    2. Turmeric Powder: If you prefer natural sources, turmeric powder is still a great option. Add it to your smoothies, teas, or curries to get some of the benefits of curcumin.
    3. Golden Milk: This traditional Indian drink is a delicious way to enjoy the benefits of turmeric. Mix turmeric powder with warm milk (or a plant-based alternative), add some black pepper and honey, and enjoy a soothing, anti-inflammatory beverage.
    4. Turmeric Capsules: If you’re looking for a convenient option, turmeric capsules are an easy way to incorporate curcumin into your diet without the taste of turmeric.

    Potential Side Effects and Considerations

    Curcumin is generally safe for most people when taken in moderate doses. However, in some cases, it can cause digestive issues, especially in high doses. If you have gallbladder problems or are on blood-thinning medications, consult your doctor before taking curcumin supplements.

    Additionally, because curcumin can enhance bile production, those with bile duct obstructions should avoid it. As with any supplement, it’s always best to talk to a healthcare professional to determine the right dosage and ensure it’s safe for you.

    Recommended Dose

    The recommended dose of curcumin for most adults is typically between 500 to 2,000 mg per day, depending on the reason for use. For general health and wellness, a dose of 500-1,000 mg per day is often sufficient. If using curcumin for specific conditions like inflammation or joint pain, some studies suggest taking up to 1,500-2,000 mg per day.

    It’s important to note that curcumin has low natural bioavailability, so it’s best taken with black pepper extract (piperine) to enhance absorption. Many curcumin supplements already include piperine for this reason.

    Always start with a lower dose to see how your body reacts, and consult with a healthcare professional to determine the right dose for your individual needs.

    Curcumin is a true super compound that offers a wide range of health benefits, from fighting inflammation and boosting brain health to supporting heart health and even helping to prevent cancer. Whether you incorporate it into your diet through turmeric or take it as a supplement, adding curcumin to your routine is a simple way to protect your body from disease and enhance your overall well-being.

    Give curcumin a try, and you might just discover a powerful ally in your quest for better health, just as I did. Buy here.

    #arthritis #curcumin #jointPain #supplements

  10. #Cannabidiol (#CBD): a killer for #inflammatory rheumatoid #arthritis synovial fibroblasts

    Published: 01 September 2020
    by Torsten Lowin, et al.

    Abstract:

    "Cannabidiol (CBD) is a non-intoxicating phytocannabinoid from cannabis sativa that has demonstrated anti-inflammatory effects in several inflammatory conditions including arthritis. However, CBD binds to several receptors and enzymes and, therefore, its mode of action remains elusive. In this study, we show that CBD increases intracellular calcium levels, reduces cell viability and IL-6/IL-8/MMP-3 production of rheumatoid arthritis synovial fibroblasts (RASF). These effects were pronounced under inflammatory conditions by activating transient receptor potential ankyrin (TRPA1), and by opening of the mitochondrial permeability transition pore. Changes in intracellular calcium and cell viability were determined by using the fluorescent dyes Cal-520/PoPo3 together with cell titer blue and the luminescent dye RealTime-glo. Cell-based impedance measurements were conducted with the XCELLigence system and TRPA1 protein was detected by flow cytometry. Cytokine production was evaluated by ELISA. CBD reduced cell viability, proliferation, and IL-6/IL-8 production of RASF. Moreover, CBD increased intracellular calcium and uptake of the cationic viability dye PoPo3 in RASF, which was enhanced by pre-treatment with TNF. Concomitant incubation of CBD with the TRPA1 antagonist A967079 but not the TRPV1 antagonist capsazepine reduced the effects of CBD on calcium and PoPo3 uptake. In addition, an inhibitor of the mitochondrial permeability transition pore, cyclosporin A, also blocked the effects of CBD on cell viability and IL-8 production. PoPo3 uptake was inhibited by the voltage-dependent anion-selective channel inhibitor DIDS and Decynium-22, an inhibitor for all organic cation transporter isoforms. CBD increases intracellular calcium levels, reduces cell viability, and IL-6/IL-8/MMP-3 production of RASF by activating TRPA1 and mitochondrial targets. This effect was enhanced by pre-treatment with TNF suggesting that CBD preferentially targets activated, pro-inflammatory RASF. Thus, CBD possesses anti-arthritic activity and might ameliorate arthritis via targeting synovial fibroblasts under inflammatory conditions."

    Source:
    nature.com/articles/s41419-020

    #Cannabis #AntiInflammatory #BigPharma #HempBan #CBDBan

  11. The link btw obesity and arthritis: ~25% of arthritis cases would have been averted by maintaining normal weight from young adulthood to midlife, sparing 2.7 million people.

    pubmed.ncbi.nlm.nih.gov/323749

    #NICHDImpact #Obesity #Overweight #Health #Arthritis #Cohort #PublicHealth