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  1. It is great to see that the background genelist problem in pathway enrichment is getting picked up in different domain areas. Like here in GWAS/exome analysis.
    #genomics #bioinformatics #pathwayEnrichment
    biorxiv.org/content/10.64898/2

  2. #Bioinformatics #HiveMind #PathwayEnrichment
    Yes, I understand there are many flaws in doing pathway analysis and lots of ways to do it.

    What are you favorite *locally programmatic* ways of doing enrichment, i.e. directly within R and related.

    I've had results that I tend to think are reasonable using the web interface to gProfileR with no electronic GO, limited category size, etc.

    Other favorites? Thoughts on gProfileR2 package versus web results?