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#orbitofrontalcortex — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #orbitofrontalcortex, aggregated by home.social.

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  1. How does the #brain adapt when goals change? This study shows that coordinated neural rhythms between medial #OrbitofrontalCortex & #hippocampus underlie flexible #navigation, allowing animals to rapidly update internal maps & switch between target locations @PLOSBiology plos.io/4x5yN2M

  2. How does the #brain adapt when goals change? This study shows that coordinated neural rhythms between medial #OrbitofrontalCortex & #hippocampus underlie flexible #navigation, allowing animals to rapidly update internal maps & switch between target locations @PLOSBiology plos.io/4x5yN2M

  3. How does the #brain adapt when goals change? This study shows that coordinated neural rhythms between medial #OrbitofrontalCortex & #hippocampus underlie flexible #navigation, allowing animals to rapidly update internal maps & switch between target locations @PLOSBiology plos.io/4x5yN2M

  4. How does the #brain adapt when goals change? This study shows that coordinated neural rhythms between medial #OrbitofrontalCortex & #hippocampus underlie flexible #navigation, allowing animals to rapidly update internal maps & switch between target locations @PLOSBiology plos.io/4x5yN2M

  5. How does the #brain adapt when goals change? This study shows that coordinated neural rhythms between medial #OrbitofrontalCortex & #hippocampus underlie flexible #navigation, allowing animals to rapidly update internal maps & switch between target locations @PLOSBiology plos.io/4x5yN2M

  6. In standard models of choice, we evaluate each option separately, then compare values. @benhayden explores a @PLOSBiology study showing that #OrbitofrontalCortex compares before evaluating, challenging theories about how we choose. Paper: plos.io/4mxK3i6 Primer: plos.io/45HPmpC

  7. In standard models of choice, we evaluate each option separately, then compare values. @benhayden explores a @PLOSBiology study showing that #OrbitofrontalCortex compares before evaluating, challenging theories about how we choose. Paper: plos.io/4mxK3i6 Primer: plos.io/45HPmpC

  8. In standard models of choice, we evaluate each option separately, then compare values. @benhayden explores a @PLOSBiology study showing that #OrbitofrontalCortex compares before evaluating, challenging theories about how we choose. Paper: plos.io/4mxK3i6 Primer: plos.io/45HPmpC

  9. In standard models of choice, we evaluate each option separately, then compare values. @benhayden explores a @PLOSBiology study showing that #OrbitofrontalCortex compares before evaluating, challenging theories about how we choose. Paper: plos.io/4mxK3i6 Primer: plos.io/45HPmpC

  10. In standard models of choice, we evaluate each option separately, then compare values. @benhayden explores a @PLOSBiology study showing that #OrbitofrontalCortex compares before evaluating, challenging theories about how we choose. Paper: plos.io/4mxK3i6 Primer: plos.io/45HPmpC

  11. When choosing between options with multiple attributes, the #OrbitofrontalCortex (OFC) is thought to integrate across attributes. @erinLrich &co show that OFC neurons encode comparisons between attributes of the same type, rather than integrating values @PLOSBiology plos.io/4mxK3i6

  12. When choosing between options with multiple attributes, the #OrbitofrontalCortex (OFC) is thought to integrate across attributes. @erinLrich &co show that OFC neurons encode comparisons between attributes of the same type, rather than integrating values @PLOSBiology plos.io/4mxK3i6

  13. When choosing between options with multiple attributes, the #OrbitofrontalCortex (OFC) is thought to integrate across attributes. @erinLrich &co show that OFC neurons encode comparisons between attributes of the same type, rather than integrating values @PLOSBiology plos.io/4mxK3i6

  14. When choosing between options with multiple attributes, the #OrbitofrontalCortex (OFC) is thought to integrate across attributes. @erinLrich &co show that OFC neurons encode comparisons between attributes of the same type, rather than integrating values @PLOSBiology plos.io/4mxK3i6

  15. When choosing between options with multiple attributes, the #OrbitofrontalCortex (OFC) is thought to integrate across attributes. @erinLrich &co show that OFC neurons encode comparisons between attributes of the same type, rather than integrating values @PLOSBiology plos.io/4mxK3i6

  16. Still doing #neuroscience.

    Our #orbitofrontalcortex (#OFC) paper published in _Neuron_ today. (Also available in #biorxiv.)

    Paul Cunningham, A. David Redish (2025) Opposing, multiplexed information in lateral and ventral orbitofrontal cortex guides sequential foraging decisions in rats Neuron.

    cell.com/neuron/abstract/S0896

    Key insights:

    1. VO and LO are doing opposite things: LO is about immediate value, while VO is about opportunity costs.

    2. OFC neurons are representing both task state (through which neurons are active) and value (as the total activity).

  17. Still doing #neuroscience.

    Our #orbitofrontalcortex (#OFC) paper published in _Neuron_ today. (Also available in #biorxiv.)

    Paul Cunningham, A. David Redish (2025) Opposing, multiplexed information in lateral and ventral orbitofrontal cortex guides sequential foraging decisions in rats Neuron.

    cell.com/neuron/abstract/S0896

    Key insights:

    1. VO and LO are doing opposite things: LO is about immediate value, while VO is about opportunity costs.

    2. OFC neurons are representing both task state (through which neurons are active) and value (as the total activity).

  18. Still doing #neuroscience.

    Our #orbitofrontalcortex (#OFC) paper published in _Neuron_ today. (Also available in #biorxiv.)

    Paul Cunningham, A. David Redish (2025) Opposing, multiplexed information in lateral and ventral orbitofrontal cortex guides sequential foraging decisions in rats Neuron.

    cell.com/neuron/abstract/S0896

    Key insights:

    1. VO and LO are doing opposite things: LO is about immediate value, while VO is about opportunity costs.

    2. OFC neurons are representing both task state (through which neurons are active) and value (as the total activity).

  19. Still doing #neuroscience.

    Our #orbitofrontalcortex (#OFC) paper published in _Neuron_ today. (Also available in #biorxiv.)

    Paul Cunningham, A. David Redish (2025) Opposing, multiplexed information in lateral and ventral orbitofrontal cortex guides sequential foraging decisions in rats Neuron.

    cell.com/neuron/abstract/S0896

    Key insights:

    1. VO and LO are doing opposite things: LO is about immediate value, while VO is about opportunity costs.

    2. OFC neurons are representing both task state (through which neurons are active) and value (as the total activity).

  20. Still doing #neuroscience.

    Our #orbitofrontalcortex (#OFC) paper published in _Neuron_ today. (Also available in #biorxiv.)

    Paul Cunningham, A. David Redish (2025) Opposing, multiplexed information in lateral and ventral orbitofrontal cortex guides sequential foraging decisions in rats Neuron.

    cell.com/neuron/abstract/S0896

    Key insights:

    1. VO and LO are doing opposite things: LO is about immediate value, while VO is about opportunity costs.

    2. OFC neurons are representing both task state (through which neurons are active) and value (as the total activity).

  21. I find this article by Ferro just out in nature communication rdcu.be/dOzT2 is an interesting intersection between value-based decision-making, embodied cognition/active vision, and memory #reactivation or #reinstatement. Looking is doing some heavy lifting. And lookie there, I didn't even mention the #orbitofrontalcortex recordings they did!

    It caught my eye (sorry) b/c some of the scanpath analysis our lab's done in the past suggests that prior to looking at a remembered, rewarded visual target, there's an uptick in #hippocampal #ripples (Leonard et al., Current Biol 2017), which are thought to signal the underlying reactivation of task-relevant activity patterns. And of course, there's work by a number of groups on memory guidance to rewarding/goal targets, that rely on hippocampal function. Ours based on an MTL amnesic: Yoo, et al., (2020). Long-term memory and hippocampal function support predictive gaze control during goal-directed search. Journal of Vision, doi.org/10.1167/jov.20.5.10 following from Chau et al., 2011, and the changes in scanpaths and pupil responses of aging adults and people with Alzheimer's disease, too: Dragan, M. C.,et al., (2017). Behavioural Brain Research, doi.org/10.1016/j.bbr.2016.09.

    Where we choose to look says so much: see e.g. Kragel/Voss; Castelhano/Henderson, Wynn/Buchsbaum/Olsen/Ryan esp what Jordana Wynn followed up with on the scanpath reinstatements suggests a really intertwined relationship between memory, eye movements, and learning/decisions about goals. (forgive that I'm missing many others and pls add below!)

    TL;DR The foraging decision-making folks and the memory-guided vision folks need to be increasingly up in each other's business.

    Here's that Ferro link:
    rdcu.be/dOzT2

    @cogneurophys

  22. I find this article by Ferro just out in nature communication rdcu.be/dOzT2 is an interesting intersection between value-based decision-making, embodied cognition/active vision, and memory #reactivation or #reinstatement. Looking is doing some heavy lifting. And lookie there, I didn't even mention the #orbitofrontalcortex recordings they did!

    It caught my eye (sorry) b/c some of the scanpath analysis our lab's done in the past suggests that prior to looking at a remembered, rewarded visual target, there's an uptick in #hippocampal #ripples (Leonard et al., Current Biol 2017), which are thought to signal the underlying reactivation of task-relevant activity patterns. And of course, there's work by a number of groups on memory guidance to rewarding/goal targets, that rely on hippocampal function. Ours based on an MTL amnesic: Yoo, et al., (2020). Long-term memory and hippocampal function support predictive gaze control during goal-directed search. Journal of Vision, doi.org/10.1167/jov.20.5.10 following from Chau et al., 2011, and the changes in scanpaths and pupil responses of aging adults and people with Alzheimer's disease, too: Dragan, M. C.,et al., (2017). Behavioural Brain Research, doi.org/10.1016/j.bbr.2016.09.

    Where we choose to look says so much: see e.g. Kragel/Voss; Castelhano/Henderson, Wynn/Buchsbaum/Olsen/Ryan esp what Jordana Wynn followed up with on the scanpath reinstatements suggests a really intertwined relationship between memory, eye movements, and learning/decisions about goals. (forgive that I'm missing many others and pls add below!)

    TL;DR The foraging decision-making folks and the memory-guided vision folks need to be increasingly up in each other's business.

    Here's that Ferro link:
    rdcu.be/dOzT2

    @cogneurophys

  23. I find this article by Ferro just out in nature communication rdcu.be/dOzT2 is an interesting intersection between value-based decision-making, embodied cognition/active vision, and memory #reactivation or #reinstatement. Looking is doing some heavy lifting. And lookie there, I didn't even mention the #orbitofrontalcortex recordings they did!

    It caught my eye (sorry) b/c some of the scanpath analysis our lab's done in the past suggests that prior to looking at a remembered, rewarded visual target, there's an uptick in #hippocampal #ripples (Leonard et al., Current Biol 2017), which are thought to signal the underlying reactivation of task-relevant activity patterns. And of course, there's work by a number of groups on memory guidance to rewarding/goal targets, that rely on hippocampal function. Ours based on an MTL amnesic: Yoo, et al., (2020). Long-term memory and hippocampal function support predictive gaze control during goal-directed search. Journal of Vision, doi.org/10.1167/jov.20.5.10 following from Chau et al., 2011, and the changes in scanpaths and pupil responses of aging adults and people with Alzheimer's disease, too: Dragan, M. C.,et al., (2017). Behavioural Brain Research, doi.org/10.1016/j.bbr.2016.09.

    Where we choose to look says so much: see e.g. Kragel/Voss; Castelhano/Henderson, Wynn/Buchsbaum/Olsen/Ryan esp what Jordana Wynn followed up with on the scanpath reinstatements suggests a really intertwined relationship between memory, eye movements, and learning/decisions about goals. (forgive that I'm missing many others and pls add below!)

    TL;DR The foraging decision-making folks and the memory-guided vision folks need to be increasingly up in each other's business.

    Here's that Ferro link:
    rdcu.be/dOzT2

    @cogneurophys

  24. I find this article by Ferro just out in nature communication rdcu.be/dOzT2 is an interesting intersection between value-based decision-making, embodied cognition/active vision, and memory #reactivation or #reinstatement. Looking is doing some heavy lifting. And lookie there, I didn't even mention the #orbitofrontalcortex recordings they did!

    It caught my eye (sorry) b/c some of the scanpath analysis our lab's done in the past suggests that prior to looking at a remembered, rewarded visual target, there's an uptick in #hippocampal #ripples (Leonard et al., Current Biol 2017), which are thought to signal the underlying reactivation of task-relevant activity patterns. And of course, there's work by a number of groups on memory guidance to rewarding/goal targets, that rely on hippocampal function. Ours based on an MTL amnesic: Yoo, et al., (2020). Long-term memory and hippocampal function support predictive gaze control during goal-directed search. Journal of Vision, doi.org/10.1167/jov.20.5.10 following from Chau et al., 2011, and the changes in scanpaths and pupil responses of aging adults and people with Alzheimer's disease, too: Dragan, M. C.,et al., (2017). Behavioural Brain Research, doi.org/10.1016/j.bbr.2016.09.

    Where we choose to look says so much: see e.g. Kragel/Voss; Castelhano/Henderson, Wynn/Buchsbaum/Olsen/Ryan esp what Jordana Wynn followed up with on the scanpath reinstatements suggests a really intertwined relationship between memory, eye movements, and learning/decisions about goals. (forgive that I'm missing many others and pls add below!)

    TL;DR The foraging decision-making folks and the memory-guided vision folks need to be increasingly up in each other's business.

    Here's that Ferro link:
    rdcu.be/dOzT2

    @cogneurophys

  25. I find this article by Ferro just out in nature communication rdcu.be/dOzT2 is an interesting intersection between value-based decision-making, embodied cognition/active vision, and memory #reactivation or #reinstatement. Looking is doing some heavy lifting. And lookie there, I didn't even mention the #orbitofrontalcortex recordings they did!

    It caught my eye (sorry) b/c some of the scanpath analysis our lab's done in the past suggests that prior to looking at a remembered, rewarded visual target, there's an uptick in #hippocampal #ripples (Leonard et al., Current Biol 2017), which are thought to signal the underlying reactivation of task-relevant activity patterns. And of course, there's work by a number of groups on memory guidance to rewarding/goal targets, that rely on hippocampal function. Ours based on an MTL amnesic: Yoo, et al., (2020). Long-term memory and hippocampal function support predictive gaze control during goal-directed search. Journal of Vision, doi.org/10.1167/jov.20.5.10 following from Chau et al., 2011, and the changes in scanpaths and pupil responses of aging adults and people with Alzheimer's disease, too: Dragan, M. C.,et al., (2017). Behavioural Brain Research, doi.org/10.1016/j.bbr.2016.09.

    Where we choose to look says so much: see e.g. Kragel/Voss; Castelhano/Henderson, Wynn/Buchsbaum/Olsen/Ryan esp what Jordana Wynn followed up with on the scanpath reinstatements suggests a really intertwined relationship between memory, eye movements, and learning/decisions about goals. (forgive that I'm missing many others and pls add below!)

    TL;DR The foraging decision-making folks and the memory-guided vision folks need to be increasingly up in each other's business.

    Here's that Ferro link:
    rdcu.be/dOzT2

    @cogneurophys

  26. Huge honour to be part of this collaboration and study. @PMuhleKarbe has done a wonderful job analysing this data set and making some neat discoveries about #goals #hippocampus and #orbitofrontalcortex and #space
    ---
    RT @PMuhleKarbe
    Excited to share our latest work, examining how navigational goals distort the representation of space:
    Great team effort with @hannahsheahan @GiovanniPezzulo @hugospiers #SamsonChien @nico_schuck @summerfi…
    twitter.com/PMuhleKarbe/status

  27. Huge honour to be part of this collaboration and study. @PMuhleKarbe has done a wonderful job analysing this data set and making some neat discoveries about #goals #hippocampus and #orbitofrontalcortex and #space
    ---
    RT @PMuhleKarbe
    Excited to share our latest work, examining how navigational goals distort the representation of space:
    Great team effort with @hannahsheahan @GiovanniPezzulo @hugospiers #SamsonChien @nico_schuck @summerfi…
    twitter.com/PMuhleKarbe/status

  28. Huge honour to be part of this collaboration and study. @PMuhleKarbe has done a wonderful job analysing this data set and making some neat discoveries about #goals #hippocampus and #orbitofrontalcortex and #space
    ---
    RT @PMuhleKarbe
    Excited to share our latest work, examining how navigational goals distort the representation of space:
    Great team effort with @hannahsheahan @GiovanniPezzulo @hugospiers #SamsonChien @nico_schuck @summerfi…
    twitter.com/PMuhleKarbe/status

  29. Huge honour to be part of this collaboration and study. @PMuhleKarbe has done a wonderful job analysing this data set and making some neat discoveries about #goals #hippocampus and #orbitofrontalcortex and #space
    ---
    RT @PMuhleKarbe
    Excited to share our latest work, examining how navigational goals distort the representation of space:
    Great team effort with @hannahsheahan @GiovanniPezzulo @hugospiers #SamsonChien @nico_schuck @summerfi…
    twitter.com/PMuhleKarbe/status

  30. Huge honour to be part of this collaboration and study. @PMuhleKarbe has done a wonderful job analysing this data set and making some neat discoveries about #goals #hippocampus and #orbitofrontalcortex and #space
    ---
    RT @PMuhleKarbe
    Excited to share our latest work, examining how navigational goals distort the representation of space:
    Great team effort with @hannahsheahan @GiovanniPezzulo @hugospiers #SamsonChien @nico_schuck @summerfi…
    twitter.com/PMuhleKarbe/status