#mechanosensing — Public Fediverse posts

📰 "N-cadherin Adhesive Interactions Mechanically Modulate Phenotype of Pancreatic Stellate Cells via YAP-dependent Mechanosensing"
https://doi.org/doi:10.1002/smtd.202501659
https://pubmed.ncbi.nlm.nih.gov/41778319/
#Mechanosensing #Extracellular #Cadherin

📰 "N-cadherin Adhesive Interactions Mechanically Modulate Phenotype of Pancreatic Stellate Cells via YAP-dependent Mechanosensing"
https://doi.org/doi:10.1002/smtd.202501659
https://pubmed.ncbi.nlm.nih.gov/41778319/
#Mechanosensing #Extracellular #Cadherin

📰 "Regional myosin mechanosensing dysfunction under metabolic stress"
https://doi.org/doi:10.1113/JP290561
https://pubmed.ncbi.nlm.nih.gov/41369174/
#Mechanosensing #Myosin

PhD Researcher, Intestinal Mechanobiology and Inflammation
University of Stuttgart

See the full job description on jobRxiv: https://jobrxiv.org/job/university-of-stuttgart-27778-phd-researcher-intestinal-mechanobiology-and-inflammation/

#EpithelialcellBiologyIntestine #Inflammation #inflammatoryboweldisease #mechanobiology #mechanosensing #organoids #ScienceJobs #hi...
https://jobrxiv.org/job/university-of-stuttgart-27778-phd-researcher-intestinal-mechanobiology-and-inflammation/?fsp_sid=6521

PhD Researcher, Intestinal Mechanobiology and Inflammation
University of Stuttgart

See the full job description on jobRxiv: https://jobrxiv.org/job/university-of-stuttgart-27778-phd-researcher-intestinal-mechanobiology-and-inflammation/

#EpithelialcellBiologyIntestine #Inflammation #inflammatoryboweldisease #mechanobiology #mechanosensing #organoids #ScienceJobs #hi...
https://jobrxiv.org/job/university-of-stuttgart-27778-phd-researcher-intestinal-mechanobiology-and-inflammation/?fsp_sid=6192

📰 "Myosin motor dynamics and cardiac function: Insights from in vivo small-angle X-ray scattering and pressure-volume analysis"
https://doi.org/doi:10.1113/JP287759
https://pubmed.ncbi.nlm.nih.gov/41214456/
#Mechanosensing #Dynamics #Myosin

📰 "Tubulin Acetylation and the Cellular Mechanosensing and Stress Response"
https://doi.org/doi:10.1007/978-3-031-91459-1_5
https://pubmed.ncbi.nlm.nih.gov/40593209/
#Mechanosensing #Microtubule #Mechanical

📰 "Liquid-Liquid Phase Separation-Mediated Cellular-Scale Compartmentalization of Hydrogel Covalent Cross-Linking Promotes Microtubule-Based Mechanosensing"
https://doi.org/doi:10.1021/jacs.5c00079
https://pubmed.ncbi.nlm.nih.gov/40252026/
#Mechanosensing #Extracellular #Microtubule #Mechanical

Very happy to see the review I wrote on mechanosensing by the endoplasmic reticulum (ER) published @J_Cell_Sci! I’ve really enjoyed studying the ER and hope to contribute some research articles soon.

#EndoplasmicReticulum #review #mechanosensing

https://journals.biologists.com/jcs/article/138/4/JCS263503/367029/The-emerging-roles-of-the-endoplasmic-reticulum-in

📰 "Mitochondria mechanosensing: The powerhouse fueling cellular force signaling"
https://doi.org/doi:10.1016/j.cub.2024.12.006
https://pubmed.ncbi.nlm.nih.gov/39837277/
#Mechanosensing #Mechanical #Actomyosin

News from Till:

Delighted to announce a new #EPSRC project on #microfluidics to study #mechanosensing. With #WarwickUni colleagues Michael Smutny and Sascha Ott, Melikhan Tanyeri from Duquesne University, and 3i as project partner:

https://gow.epsrc.ukri.org/NGBOViewGrant.aspx?GrantRef=EP/X026663/1

New #preprint from Ardem Patapoutian's lab:

'Here, we show that humans lacking PIEZO2 exhibit impaired bowel sensation and motility. Piezo2 in mouse dorsal root but not nodose ganglia is required to sense gut content, and this activity slows down food transit rates in the stomach, small intestine, and colon. Indeed, Piezo2 is directly required to detect colon distension in vivo. Our study unveils the mechanosensory mechanisms that regulate the transit of luminal contents throughout the gut, which is a critical process to ensure proper digestion, nutrient absorption, and waste removal.'

#Mechanosensing #MucosalImmunology
#Piezo

https://www.biorxiv.org/content/10.1101/2022.11.27.518109v1?med=mas