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#mechanosensing — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #mechanosensing, aggregated by home.social.

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  1. 📰 "The kinesin-4 protein KIF27 forms a cytoskeletal scaffold at the transition zone to promote motile cilia structural integrity"
    doi.org/doi:10.1073/pnas.25153
    pubmed.ncbi.nlm.nih.gov/414009
    #Mechanosensing #Kinesin #Cell

  2. 📰 "Liquid-Liquid Phase Separation-Mediated Cellular-Scale Compartmentalization of Hydrogel Covalent Cross-Linking Promotes Microtubule-Based Mechanosensing"
    doi.org/doi:10.1021/jacs.5c000
    pubmed.ncbi.nlm.nih.gov/402520
    #Mechanosensing #Extracellular #Microtubule #Mechanical

  3. My next @preLights post is out. I saw this first preprint from the Storer lab a while back (thanks to a toot from @CellySally) and took some time over writing it but I think it was worth it!

    I really enjoyed going back to some developmental biology with this study on how the ECM and mechanical environment influence limb regeneration. Also, nice that my PhD department, PDN, was heavily involved!

    prelights.biologists.com/highl

    #preprint #regeneration #mechanosensing #ECM

  4. My next @preLights post is out. I saw this first preprint from the Storer lab a while back (thanks to a toot from @CellySally) and took some time over writing it but I think it was worth it!

    I really enjoyed going back to some developmental biology with this study on how the ECM and mechanical environment influence limb regeneration. Also, nice that my PhD department, PDN, was heavily involved!

    prelights.biologists.com/highl

    #preprint #regeneration #mechanosensing #ECM

  5. 📰 "Nanoscale distribution of bioactive ligands on biomaterials regulates cell mechanosensing through translocation of actin into the nucleus"
    doi.org/doi:10.1073/pnas.25012
    pubmed.ncbi.nlm.nih.gov/400429
    #Mechanosensing #Cytoskeleton #Cell

  6. Very happy to see the review I wrote on mechanosensing by the endoplasmic reticulum (ER) published @J_Cell_Sci! I’ve really enjoyed studying the ER and hope to contribute some research articles soon.

    #EndoplasmicReticulum #review #mechanosensing

    journals.biologists.com/jcs/ar

  7. 📰 "Biophysical and Structural Features of alphabetaT-Cell Receptor Mechanosensing: A Paradigmatic Shift in Understanding T-Cell Activation"
    doi.org/doi:10.1111/imr.13432
    pubmed.ncbi.nlm.nih.gov/397454
    #Mechanosensing #Mechanical #Cell

  8. News from Till:

    Delighted to announce a new #EPSRC project on #microfluidics to study #mechanosensing. With #WarwickUni colleagues Michael Smutny and Sascha Ott, Melikhan Tanyeri from Duquesne University, and 3i as project partner:

    gow.epsrc.ukri.org/NGBOViewGra

  9. News from Till:

    Delighted to announce a new #EPSRC project on #microfluidics to study #mechanosensing. With #WarwickUni colleagues Michael Smutny and Sascha Ott, Melikhan Tanyeri from Duquesne University, and 3i as project partner:

    gow.epsrc.ukri.org/NGBOViewGra

  10. New #preprint from Ardem Patapoutian's lab:

    'Here, we show that humans lacking PIEZO2 exhibit impaired bowel sensation and motility. Piezo2 in mouse dorsal root but not nodose ganglia is required to sense gut content, and this activity slows down food transit rates in the stomach, small intestine, and colon. Indeed, Piezo2 is directly required to detect colon distension in vivo. Our study unveils the mechanosensory mechanisms that regulate the transit of luminal contents throughout the gut, which is a critical process to ensure proper digestion, nutrient absorption, and waste removal.'

    #Mechanosensing #MucosalImmunology
    #Piezo

    biorxiv.org/content/10.1101/20