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#limma — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #limma, aggregated by home.social.

  1. Congrats to the finalists for the Eureka Prize for Excellence in Research Software, developing and maintaining , MRtrix3 and

    This prize recognises and celebrates those who develop and maintain software in Australia that underpins research and scientific discovery.
    ardc.edu.au/article/finalists-

  2. I am still deeply irritated by the fact, that limma also calculates statistics for a one-sample t-test (so, no contrasts & designs involved) with a n=1 datarow - should this not be a classical case for a "NA"? #limma #data

  3. @haojiawu @biorxivpreprint this is very interesting. I have been telling people that one of the main reasons for using #RStats instead of #python for gene expression analysis, is the lack of methods such as #DESeq2 or #limma as python libraries. This might tip the balance for a lot of people.

    Of course there are many reasons to prefer R, the excellent #Bioconductor ecosystem one of them, and in fairness, for #scRNA analysis python has very strong ecosystem and community.

  4. Wow, this paper on #scRNAseq and differential expression methods is an eye opener. nature.com/articles/s41467-021

    Nice overview of methods and relatively easy to understand explanation of what is wrong with certain, especially single-cell-specific, methods.

    Of great help in my own scRNA-seq efforts. Should probably have read this earlier. Now, back to R I go. 😅

    #statistics #rnaseq #Seurat #limma #edgeR #DESeq2