#limma — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #limma, aggregated by home.social.
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Congrats to the finalists for the Eureka Prize for Excellence in Research Software, developing and maintaining #MiniZinc, MRtrix3 and #limma
This prize recognises and celebrates those who develop and maintain software in Australia that underpins research and scientific discovery.
https://ardc.edu.au/article/finalists-announced-for-the-2024-ardc-eureka-prize-for-excellence-in-research-software/ -
@haojiawu @biorxivpreprint this is very interesting. I have been telling people that one of the main reasons for using #RStats instead of #python for gene expression analysis, is the lack of methods such as #DESeq2 or #limma as python libraries. This might tip the balance for a lot of people.
Of course there are many reasons to prefer R, the excellent #Bioconductor ecosystem one of them, and in fairness, for #scRNA analysis python has very strong ecosystem and community.
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Wow, this paper on #scRNAseq and differential expression methods is an eye opener. https://www.nature.com/articles/s41467-021-25960-2
Nice overview of methods and relatively easy to understand explanation of what is wrong with certain, especially single-cell-specific, methods.
Of great help in my own scRNA-seq efforts. Should probably have read this earlier. Now, back to R I go. 😅