#lassafever — Public Fediverse posts

Older drug reprograms white blood cells, improves blood sugar in type 1 diabetes

(This is an excerpt of the Health Rounds newsletter, where we present latest medical studies on Tuesdays and…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Health #AmericanDiabetesAssociation #BCGtreatment #bloodsugar #DeniseFaustman #Diarrhea #gutbacteria #Lassafever #Researchers #type1diabetes #whitebloodcells
https://www.newsbeep.com/us/696009/

Older drug reprograms white blood cells, improves blood sugar in type 1 diabetes

(This is an excerpt of the Health Rounds newsletter, where we present latest medical studies on Tuesdays and…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Health #AmericanDiabetesAssociation #BCGtreatment #bloodsugar #DeniseFaustman #Diarrhea #gutbacteria #Lassafever #Researchers #type1diabetes #whitebloodcells
https://www.newsbeep.com/us/696009/

https://www.europesays.com/ie/248316/ Early Release – Guinea Pig Model for Lassa Virus Infection of Reproductive Tract and Considerations for Sexual and Vertical Transmission – Volume 31, Number 12—December 2025 – Emerging Infectious Diseases journal #AnimalDiseaseModels #Éire #GuineaPigs #Health #HemorrhagicFevers #IE #Immunohistochemistry #InSituHybridization #InfectiousPregnancyComplications #Ireland #LassaFever/pathology #LassaVirus #Pathology #ReproductiveTractInfections #viruses

👀 CDC: Lassa Fever Suspected in Death of U.S. Traveler Returning from West Africa "...The CDC and the Iowa Department of Health are investigating a suspected case of Lassa fever, which was diagnosed today in an Iowa resident who returned to the United States from West Africa early this month..... The patient was hospitalized in isolation at the University of Iowa Health Care Medical Center when they died earlier this afternoon. ..." https://www.cdc.gov/media/releases/2024/s1028-lassa-fever.html
#lassafever #disease

👀 CDC: Lassa Fever Suspected in Death of U.S. Traveler Returning from West Africa "...The CDC and the Iowa Department of Health are investigating a suspected case of Lassa fever, which was diagnosed today in an Iowa resident who returned to the United States from West Africa early this month..... The patient was hospitalized in isolation at the University of Iowa Health Care Medical Center when they died earlier this afternoon. ..." https://www.cdc.gov/media/releases/2024/s1028-lassa-fever.html
#lassafever #disease

Interesting retrospective cohort analysis of suspected #LassaFever cases in #Nigeria.

Finding that case positivity rate has declined since 2018-2021 to around 10%, suggesting dramatic improvement in test availability and surveillance activity. 👏

https://doi.org/10.1038/s41598-023-33187-y

Point-of-care ultrasound #POCUS is possibly a promising low-cost imaging technique to manage most-at-risk #Lassa Fever patients.
Check out this study by @CyrilErameh @ISTH_Irrua & @infektiodoc @UKEHamburg & al. @BNITM_de publ. in the #Journal_of_Infection:
http://bit.ly/3mLHgbX
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RT @infektiodoc
Can point-of-care ultrasound be a helpful tool in the management of Lassa fever patients? – a 🧵 1/9

#POCUS
#Lassafever🐀🦠🤒
#Nigeria 🇳🇬

htt…
https://twitter.com/infektiodoc/status/1649065765872574467

Very cool to see the protocol of the #LassaFever epidemiology study by @CEPIvaccines in print @PLOSNTDs. Intensive active surveillance should be useful.

https://doi.org/10.1371/journal.pone.0283643

Shame no combined rodent work but a useful baseline of human epi to combine with future rodent work.

Latest @NCDCgov #LassaFever report highlights impacts of external events on surveillance. Feb 2019 and 2023 showed earlier precipitous drops in case numbers than expected.

Likely due to Presidential election, both years showing rebound in cases after election.

#Zoonoses

A great first step in developing a #LassaFever vaccine for human use. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)00048-X/fulltext#%20

First time in human trial, assessing safety and tolerability of a vaccine. Long way to go to get it into the arms of people who need it most.

If you look you find!

My understanding is that prior to this week #Ghana had only recorded 2 cases of #LassaFever since 2011. 12 additional cases identified from contact tracing, and 1 probable case from a distant region suggest further epidemiological work is required.
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RT @_GHSofficial
❗️PRESS RELEASE ❗️
Update on Lassa Fever Outbreak in Ghana -28th February 2023 https://t.co/ASSLIjvCkV
https://twitter.com/_GHSofficial/status/1630698854440919041

#LassaFever reported from Ghana. Considered endemic but does not regularly report cases. The fact that the first case was only identified post-mortem highlights why.

A previous study showed prevalence of antibodies in humans but limited rodent studies. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215224
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RT @_GHSofficial
❗️PRESS RELEASE ❗️
Two Confirmed Lassa Fever Cases in Ghana
https://twitter.com/_GHSofficial/status/1629754687871172608

So, if we truly want to understand the changing risk of #LassaFever and other rodent borne endemic zoonoses under climate change, landuse change and population/development. I think we need one of these. 2-3 year studies are not enough.

Who wants to find me 😂
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RT @RoyalSocBio
The Biologist looks at some of the UK's longest running field experiments – some of which have been running for over a century – and how they can tell us thin…
https://twitter.com/RoyalSocBio/status/1628400718569693185

Fantastic to see this published! A seroprevalence study for Lassa Fever conducted by the #SierraLeonean KGH #LassaFever team and #TulaneUniversity team. Can stop using the 1970's reference now 🤣 .

Most importantly they found seroprevalence >50% from villages across the country. This overturns orthodoxy of limited distribution of #LassaFever within the country. Much more effort is required to understand this spatial heterogeneity. Which unfortunately means longer and more expensive studies.

Fantastic to see this published! A seroprevalence study for Lassa Fever conducted by the #SierraLeonean KGH #LassaFever team and #TulaneUniversity team. Can stop using the 1970's reference now 🤣 .

Most importantly they found seroprevalence >50% from villages across the country. This overturns orthodoxy of limited distribution of #LassaFever within the country. Much more effort is required to understand this spatial heterogeneity. Which unfortunately means longer and more expensive studies.

Dr Mirjam Groger @BNITM_de is awarded the #WolfgangStillePreis 2022! The @PaulEhrlichGes honours her & an international cross institutional research team @ISTH_Irrua @UKEHamburg @unihh for their clinical studies on the medical treatment of #Lassafever.
👉🏾http://bit.ly/3xnLpVm

Kicking off training on a novel #LuciferaseImmunoprecipitation assay for #LassaFever @UniversityNjala developed by Isobel Honeyborne among others as part of a #OneHealth @PandoraIDNet project to understand Lassa transmission in Sierra Leone.

#LassaFever case counts in week 2 from #Nigeria. Greatest number of cases ever detected at the beginning of the year. The annual trend of <20 cases per week in December to >80 cases per week in January.

Would love to be able to study this more. This appears to me too synchronised to be driven by purely rodent factors.

#LassaFever case counts in week 2 from #Nigeria. Greatest number of cases ever detected at the beginning of the year. The annual trend of <20 cases per week in December to >80 cases per week in January.

Would love to be able to study this more. This appears to me too synchronised to be driven by purely rodent factors.

A nice study of #LassaFever in #Guinea by @stephanie200586 and colleagues. https://wwwnc.cdc.gov/eid/article/29/2/21-2525_article

Found evidence that fractured habitats are associated with increased exposure.

Seroprevalence up to 59% but so few clinical cases reported from Guinea. <20 in 10 years. 🤔

I am particularly interested in rodent-borne zoonosis spillover into human populations in #WestAfrica. I am studying #LassaFever but this is one of many viral and bacterial zoonoses in the region. This work collates and synthesises rodent trapping studies to understand sampling.

I am particularly interested in rodent-borne zoonosis spillover into human populations in #WestAfrica. I am studying #LassaFever but this is one of many viral and bacterial zoonoses in the region. This work collates and synthesises rodent trapping studies to understand sampling.

I've been frustrated with some of the numbers reported when discussing #LassaFever this hopefully quantifies some of the uncertainty around numbers of reported cases.

Would love to explore further if of interest to those who hold the data. @NCDCgov @Chikwe_I
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RT @RSTMH
New in our journal #InternationalHealth: David Simons (@David_Simons_UK) highlights current uncertainty and systemic underreporting of the morbidity and mortality burden …
https://twitter.com/RSTMH/status/1597590039768498177