#immunosky — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #immunosky, aggregated by home.social.
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Fascinating paper. Not only association between auto antibodies against immunotegulatory IL-10 and some patients with inflammatory bowel disease. But also association between these antibodies and HLA risk allele for IBD. What's mechanistic link? #immunosky #MedSky www.nejm.org/doi/full/10....
Interleukin-10 Autoantibodies ... -
https://bsky.app/profile/inflames-flagship.bsky.social/post/3mnc3n4velc2v #UTU #yliopisto We are so lucky, we have brilliant Professor David G Shazt from Yale School of Medicine as keynote speaker at ImmuDocs and IFDM summer seminar! Cool!
#ImmunoSky #MedSky #FinnishFlagships
@utu.fi -
this is cool - haematopoietic stem cell subsets that remember inflammatory cues. Link to human disease mortality a bit loose, personally, and not much functional readout of progenitor cells. Still, paper concept interesting, and yet another single cell popn to hunt in own datasets.... #ImmunoSky
RE: https://bsky.app/profile/did:plc:vt765hjdontyunsxk7bslksv/post/3mn3dyhzm7s2h -
https://bsky.app/profile/inflames-flagship.bsky.social/post/3mmqxqqdpuk2e #UTU #yliopisto Uusi aivokuvantamistutkimus ei löytänyt pitkittyneistä koronataudin oireista kärsivien potilaiden aivoista laaja-alaista aivotulehdusta. Sen sijaan voimakkaimmat long covid-oireet olivat yhteydessä lisääntyneeseen aktivaatioon alueilla, jotka liittyvät mielialaan ja tunteisiin.
#ImmunoSky #TSPO-PET
https://inflames.utu.fi/aivotulehdus-on-epatodennakoinen-syy-pitkittyneisiin-koronaoireisiin/ -
https://bsky.app/profile/utu.fi/post/3mlsha5oeik2i #UTU #yliopisto Professor Shimon Sakaguchi discovered a completely new type of immune cell, regulatory T cell, and was awarded the 2025 Nobel Prize in Medicine for his research. During his visit to the University of Turku he explained us the clinical relevance of these cells which is significant.
#ImmunoSky
https://www.utu.fi/en/news/news/regulatory-t-cells-discovered-by-shimon-sakaguchi-maintain-order-in-the-body -
https://bsky.app/profile/utu.fi/post/3mlsg65w75h2w #UTU #yliopisto Professori ja lääketieteen nobelisti Shimon Sakaguchi kertoi Turun vierailullaan tutkimuksestaan, joka johti täysin uuden solutyypin, T-säätelijäsolun, löytymiseen. Löytöä voidaan hyödyntää muun muassa kun kehitetään uusia hoitoja autoimmuunisairauksiin.
#ImmunoSky #MedSky
Lahesmaa Lab -
https://bsky.app/profile/inflames-flagship.bsky.social/post/3mlseyjkprc27 #UTU #yliopisto We had an honour to talk with Nobel laureate, professor Shimon Sakaguchi during his visit to the University of Turku. He explained which research finding was key to his discovery of regulatory T-cells and how he now views the clinical relevance of this cell type.
#ImmunoSky
@lahesmaalab.bsky.social
https://inflames.utu.fi/regulatory-t-cells-discovered-by-shimon-sakaguchi-maintain-order-in-the-body/ -
https://bsky.app/profile/inflames-flagship.bsky.social/post/3mlsdwivnn22r #UTU #yliopisto Tapasimme nobelistin, professorin ja maailmankuulun immunologin Shimon Sakaguchin hänen vieraillessaan Turun yliopistossa. Hän kertoi, mikä tutkimus oli hänen T-säätelijäsolulöydölleen ratkaiseva ja antoi myös neuvoja nuoremmille tutkijoille.
#ImmunoSky #MedSky
@lahesmaalab.bsky.social
https://inflames.utu.fi/nobelisti-shimon-sakaguchin-loytama-t-saatelijasolu-on-elimiston-jarjestyksenvalvoja/ -
https://bsky.app/profile/inflames-flagship.bsky.social/post/3mlnjaymjt22l #UTU #yliopisto Full house in Turku for Nobel Laureate, Professor Shimon Sakaguchi. It's such a honor to have him here!
#MedSky #ImmunoSky #Science
@utu.fi @lahesmaalab.bsky.social -
https://bsky.app/profile/utu.fi/post/3mldm3hkwza2i #UTU #yliopisto Nobel-palkittu professori Shimon Sakaguchi luennoi Turun yliopistossa tiistaina 12.5. Sakaguchin löydökset ovat luoneet uusia mahdollisuuksia muun muassa syöpien ja autoimmuunisairauksien hoitojen kehittämiseen.
#MedSky #ImmunoSky #Treg
Lahesmaa Lab Turku Bioscience -
https://bsky.app/profile/inflames-flagship.bsky.social/post/3mldm3hi62z2v #UTU #yliopisto Nobel-palkittu professori Shimon Sakaguchi luennoi Turun yliopistossa tiistaina 12.5. Sakaguchin löydökset ovat luoneet uusia mahdollisuuksia muun muassa syöpien ja autoimmuunisairauksien hoitojen kehittämiseen.
#MedSky #ImmunoSky #Treg
Lahesmaa Lab Turku Bioscience -
Nice demonstration by @[email protected] et al that some, but not all, non tuberculous mycobacteria (NTM) intracellular growth in macrophages is pH sensitive #TBSky #immunosky onlinelibrary.wiley.com/doi/10.1111/...
Acidic pH Restricts Non‐Tuberc... -
This is really rather cool - macrophages nibbling live cells to maintain immune tolerance. A must for journal club soon... #immunosky
RE: https://bsky.app/profile/did:plc:px3rjj3utp3bkfchk2vmqm5p/post/3mknf2p62rs2c -
https://bsky.app/profile/inflames-flagship.bsky.social/post/3mkmwsygbc22m #UTU #yliopisto Happy wishes from InFLAMES Flagship Finland on a International Day of Immunology!
#ImmunoSky #medsky #FinnishFlagships
@utu.fi @aboakademi.bsky.social @iuis-online.bsky.social @yefis-immunology.bsky.social @yssi-immunology.bsky.social -
Love this - all marketing is good marketing. Even immune markers have an age and significant milestones. CD40 - important molecule - not to be sniffed at! #ImmunoSky
RE: https://bsky.app/profile/did:plc:czhpd6buktkiv23zghhohq22/post/3mk3kkino7m2n -
Great progress on vaccines & host-directed therapies (HDT) in TB. Our review on IL-17👇 🎯protective early on & post-vaccine in animal models 👉desirable for vaccines? 🎯Drive pathology in TB disease👉target for HDT to limit post-TB lung damage? With @[email protected] @[email protected] #TBSky #ImmunoSky
Context-specific roles for IL-... -
Great progress on vaccines & host-directed therapies (HDT) in TB. Our review on IL-17👇 🎯protective early on & post-vaccine in animal models 👉desirable for vaccines? 🎯Drive pathology in TB disease👉target for HDT to limit post-TB lung damage? With @[email protected] @[email protected] #TBSky #ImmunoSky
Context-specific roles for IL-... -
https://bsky.app/profile/inflames-flagship.bsky.social/post/3mjyxehdev22l Soon we´ll have a chance to listen to our new clinical researchers Lauri Ivaska, Jukka Kero and Eero Rissanen. Excellent!
#Medsky #ImmunoSky #Science #immunology
@lauriivaska.bsky.social
@utu.fi #UTU #yliopisto -
https://bsky.app/profile/inflames-flagship.bsky.social/post/3mhdlgzvgx222 Lääketieteen tohtori Antti Hurme on aloittanut Turun Immunologiakeskuksen kliinisenä johtajana! Hän aikoo toimia siltana immunologisen perustutkimuksen ja klinikan välillä.
Onnea Antille!
#ImmunoSky #MedSky #ScienceSky
https://inflames.utu.fi/antti-hurme-aloitti-turun-immunologiakeskuksen-kliinisena-johtajana-tavoitteena-tutkimuksen-ja-klinikan-yh #utu #yliopisto -
https://bsky.app/profile/inflames-flagship.bsky.social/post/3mf4oa6i2zc2r Our researchers have discovered that the surface cells of the lymphatic vessels in oral cancer contain proteins that indicate cell division and strongly predict disease progression and mortality.
@salmilab.bsky.social @turkubioscience.bsky.social
#ImmunoSky #MedSky
https://inflames.utu.fi/aggressive-oral-cancer-can-be-identified-at-an-early-stag #utu #yliopisto -
https://bsky.app/profile/inflames-flagship.bsky.social/post/3mdnout7fjb2x Lääketieteessä ja lääkekehityksessä tutkimus on painottunut miehiin. Mutta onko niin, että miesbiologiasta kumpuavat tutkimustulokset ovat suoraan sovellettavissa naisiin? Mm. tätä pohdittiin InFLAMESin Sex and Immunity-teeman Corporate Corner -seminaarissa.
#ImmunoSky #MedSky #immunologiahttps://www.utu.fi/fi/ajankohtaista/uutinen/nainen-ei-o #utu #yliopisto
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https://bsky.app/profile/inflames-flagship.bsky.social/post/3mdmwsz4vds24 Ryhmänjohtamme, neuroimmunologian professori Laura Airas kertoo Turun Sanomissa monin tavoin yllättävästä MS- lääketutkimuksesta!
#lääkekehitys #MedSky #ImmunoSKY #MS
@utu.fi[contains quote post or other embedded content] #utu #yliopisto
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https://bsky.app/profile/inflames-flagship.bsky.social/post/3mdfgf5mkss2h Kateenkorva on keskeinen osa immuunijärjestelmää, sitä ei aina muisteta. Mielenkiintoinen tutkimus!
#ImmunoSky #MedSky #immunologia
https://tekniikanmaailma.fi/nytko-se-loytyi-uusi-tapa-pitaa-immuunijarjestelma-nuorena-pitkaan-tutkimus/ #utu #yliopisto -
https://bsky.app/profile/inflames-flagship.bsky.social/post/3mcz4xd7jb22j Think about this: Women's health receives only 1% of research funding if oncology is excluded. Not cool. Our Corporate Corner is in full swing! #Sex&Immunity
#medsky #immunosky
@utu.fi #utu #yliopisto -
https://bsky.app/profile/inflames-flagship.bsky.social/post/3mcytk6mbes2i TODAY! Let's find out has the one-size-fits-all research failed to capture biologically meaningful sex differences. What do you think?
#immunosky #medsky #FinnishFlagships #immunology
@utu.fi @aboakademi.bsky.social #utu #yliopisto -
https://bsky.app/profile/inflames-flagship.bsky.social/post/3mhdlgzvgx222 Lääketieteen tohtori Antti Hurme on aloittanut Turun Immunologiakeskuksen kliinisenä johtajana! Hän aikoo toimia siltana immunologisen perustutkimuksen ja klinikan välillä.
Onnea Antille!
#ImmunoSky #MedSky #ScienceSky
https://inflames.utu.fi/antti-hurme-aloitti-turun-immunologiakeskuksen-kliinisena-johtajana-tavoitteena-tutkimuksen-ja-klinikan-yh #utu #yliopisto -
https://bsky.app/profile/inflames-flagship.bsky.social/post/3mf4oa6i2zc2r Our researchers have discovered that the surface cells of the lymphatic vessels in oral cancer contain proteins that indicate cell division and strongly predict disease progression and mortality.
@salmilab.bsky.social @turkubioscience.bsky.social
#ImmunoSky #MedSky
https://inflames.utu.fi/aggressive-oral-cancer-can-be-identified-at-an-early-stag #utu #yliopisto -
https://bsky.app/profile/inflames-flagship.bsky.social/post/3mdnout7fjb2x Lääketieteessä ja lääkekehityksessä tutkimus on painottunut miehiin. Mutta onko niin, että miesbiologiasta kumpuavat tutkimustulokset ovat suoraan sovellettavissa naisiin? Mm. tätä pohdittiin InFLAMESin Sex and Immunity-teeman Corporate Corner -seminaarissa.
#ImmunoSky #MedSky #immunologiahttps://www.utu.fi/fi/ajankohtaista/uutinen/nainen-ei-o #utu #yliopisto
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https://bsky.app/profile/inflames-flagship.bsky.social/post/3mdmwsz4vds24 Ryhmänjohtamme, neuroimmunologian professori Laura Airas kertoo Turun Sanomissa monin tavoin yllättävästä MS- lääketutkimuksesta!
#lääkekehitys #MedSky #ImmunoSKY #MS
@utu.fi[contains quote post or other embedded content] #utu #yliopisto
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https://bsky.app/profile/inflames-flagship.bsky.social/post/3mdfgf5mkss2h Kateenkorva on keskeinen osa immuunijärjestelmää, sitä ei aina muisteta. Mielenkiintoinen tutkimus!
#ImmunoSky #MedSky #immunologia
https://tekniikanmaailma.fi/nytko-se-loytyi-uusi-tapa-pitaa-immuunijarjestelma-nuorena-pitkaan-tutkimus/ #utu #yliopisto -
https://bsky.app/profile/inflames-flagship.bsky.social/post/3mcz4xd7jb22j Think about this: Women's health receives only 1% of research funding if oncology is excluded. Not cool. Our Corporate Corner is in full swing! #Sex&Immunity
#medsky #immunosky
@utu.fi #utu #yliopisto -
https://bsky.app/profile/inflames-flagship.bsky.social/post/3mcytk6mbes2i TODAY! Let's find out has the one-size-fits-all research failed to capture biologically meaningful sex differences. What do you think?
#immunosky #medsky #FinnishFlagships #immunology
@utu.fi @aboakademi.bsky.social #utu #yliopisto -
https://bsky.app/profile/inflames-flagship.bsky.social/post/3mf4oa6i2zc2r Our researchers have discovered that the surface cells of the lymphatic vessels in oral cancer contain proteins that indicate cell division and strongly predict disease progression and mortality.
@salmilab.bsky.social @turkubioscience.bsky.social
#ImmunoSky #MedSky
https://inflames.utu.fi/aggressive-oral-cancer-can-be-identified-at-an-early-stag #utu #yliopisto -
https://bsky.app/profile/inflames-flagship.bsky.social/post/3mhdlgzvgx222 Lääketieteen tohtori Antti Hurme on aloittanut Turun Immunologiakeskuksen kliinisenä johtajana! Hän aikoo toimia siltana immunologisen perustutkimuksen ja klinikan välillä.
Onnea Antille!
#ImmunoSky #MedSky #ScienceSky
https://inflames.utu.fi/antti-hurme-aloitti-turun-immunologiakeskuksen-kliinisena-johtajana-tavoitteena-tutkimuksen-ja-klinikan-yh #utu #yliopisto -
https://bsky.app/profile/inflames-flagship.bsky.social/post/3mdnout7fjb2x Lääketieteessä ja lääkekehityksessä tutkimus on painottunut miehiin. Mutta onko niin, että miesbiologiasta kumpuavat tutkimustulokset ovat suoraan sovellettavissa naisiin? Mm. tätä pohdittiin InFLAMESin Sex and Immunity-teeman Corporate Corner -seminaarissa.
#ImmunoSky #MedSky #immunologiahttps://www.utu.fi/fi/ajankohtaista/uutinen/nainen-ei-o #utu #yliopisto
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https://bsky.app/profile/inflames-flagship.bsky.social/post/3mdmwsz4vds24 Ryhmänjohtamme, neuroimmunologian professori Laura Airas kertoo Turun Sanomissa monin tavoin yllättävästä MS- lääketutkimuksesta!
#lääkekehitys #MedSky #ImmunoSKY #MS
@utu.fi[contains quote post or other embedded content] #utu #yliopisto
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Epithelial host pathogen interactions are complex! Happy to have contributed to this work, showing how mutations in Streptococcus pneumoniae biosynthesis genes results in divergent phenotyoic effects and host transcriptional responses (the bit I did!) #IDSky #immunosky @[email protected]
Disease-Attenuated Pneumococca... -
More adjunctive immunomodulation for an infectious disease! Here it's dupilumab (IL-4/13 blockade) in coccidioidomycosis. Case series only, but not overtly harmful and maybe even helpful. #IDSky #immunosky academic.oup.com/cid/advance-...
Immunomodulation in the Treatm... -
Love this kind of science. Human integrin LFA-1 considered important for T cell skin homing. But how important is it really? Looking at genetic deficient individuals, turns out LFA-1 essential for clearing commensal papillomaviruses, but redundant for most else! @[email protected] #ImmunoSky
Human LFA-1 governs T cell imm... -
This is a very appealing meeting in Paris later this year... "The complexity of mycobacterial infections: from research to real-world impact" #EMBOComplexInfections #TBSky for the tuberculosis research, but also #NTM #Leprosy #IDSky #ImmunoSky meetings.embo.org/event/26-myc...
The complexity of mycobacteria... -
IL-23 is a highly targeted cytokine vs autoimmune disease. But here with an oral agent! @nejm.org #ImmunoSky #MedSky www.nejm.org/doi/full/10....
Oral Icotrokinra for Plaque Ps... -
Host-directed therapies for infectious disease are here & coming! Simple equation proposed to consider best interventions: ⭐ Microorganism + immune response = clinical presentation/status ⭐ Will require futuristic-sounding real-time diagnostics = exciting! #IDSky #MedSky #ImmunoSky #TBSky
The Changing Paradigm in Infec... -
There you go - TB shaping the immune system (MHC class II) of meerkats! #TBSky #ImmunoSky 🧪 www.nature.com/articles/s41...
Twenty years of tuberculosis-d... -
Speed conference dating @ #IUIS2025! 😅 #ImmunoSky
RE: https://bsky.app/profile/did:plc:lejmggi35is2bys7mwc5pjc2/post/3lwqkgfmjmt2f -
I think someone accidentally copied and pasted "Manuscript title:" into the title field! 🤭 (also quite an interesting #malaria immunology study!) #IDSky #ClinMicro #medsky #immunosky #AcademicSky academic.oup.com/jid/advance-...
Manuscript title: Cytokines As... -
Another immune mechanism in TB in which a seemingly host protective response (immunothrombosis) may get out of hand and drive tissue pathology. @jidjournal.bsky.social #IDSky #TBSky #ImmunoSky 🧪
The emerging role of immunothr... -
As paper titles involving TB go, this one using the rhyming Fc is not bad... (also a good synopsis of an important paper) #IDSky #TBSky #immunosky www.science.org/doi/10.1126/...
TB or not TB: That depends on ... -
This is good news. Comparable immune responses (IgA & neutralising antibodies) with new oral polio vaccine compared to Sabin vaccine - hopefully can help interrupt circulating vaccine-derived poliovirus outbreaks. @lancetmicrobe.bsky.social #IDSky #ImmunoSky www.thelancet.com/journals/lan...
Intestinal mucosal immune resp... -
I honestly thought it was a given that neutrophil elastase was important in controlling Staph aureus infection! @jidjournal.bsky.social #immunosky academic.oup.com/jid/advance-...
Neutrophil elastase limits spr... -
And TBH @europepmc.org has more & better features, like @altmetric.com integration for one! #MedSky #immunosky #IDSky #AcademicSky
RE: https://bsky.app/profile/did:plc:a4mdbabyn4u3yxzh5o7hzlxl/post/3ljdh7ckzs22q -
The evidence is overwhelming. Denying viruses is denying reality. Science works. If you’re unsure, follow experts in virology, immunology, molecular biology, and epidemiology, not conspiracy theories.
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Immune evasion through mitochondrial transfer in the tumour microenvironment
Identification of mitochondrial DNA (mtDNA) mutations in TILs that are shared with cancer cells, and are derived from the tumour cells.
#ImmunoSky #MedSky -
Precursors of exhausted T cells are preemptively formed in acute infection
At that stage early precursors show diversity; memory T cells but also cells with a phenotype, gene-expression, and epigenetic profile that resembles precursors of exhausted T cells. #ImmunoSky
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🚨 Delighted to share our paper defining a new role for IL-6 in TB. 🚨 We used genetic variation to show *reduced* IL-6 signalling is causally associated with *lower* risk of TB. Lead author @gushamilton.bsky.social #TBSky #IDSky #ImmunoSky www.thelancet.com/journals/lan... Thread 👇 (1/8)
Altered IL-6 signalling and ri... -
Cool new paper - lockdowns have indirect immunological consequences on disease susceptibility 👏 @apsmunro.bsky.social & @tah-sci.bsky.social #IDSky 🩺 #virology #MicroSky #ImmunoSky academic.oup.com/cid/advance-...
Cycles of susceptibility: Immu... -
MicroRNAs won the Nobel — will they ever be useful as medicines? #Science #MedSky #ImmunoSky www.nature.com/artic...
MicroRNAs won the Nobel — will... -
'Human inborn errors of the type I IFN response pathway and auto-Abs neutralizing IFN-α, -β, and/or -ω can underlie severe viral illnesses. We report a simple assay for the detection of both types of condition.'
