#acetylation — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #acetylation, aggregated by home.social.
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Loss of metabolic control mechanisms promotes uncontrolled cancer cell proliferation
Researchers from the University of Seville have participated in research to identify the molecular details of the regulation…
#NewsBeep #News #Health #Acetylation #AU #Australia #Cancer #Cell #CellProliferation #Enzyme #Fruit #Kinase #Metabolism #Proliferation #research
https://www.newsbeep.com/au/432382/ -
https://www.europesays.com/ie/186315/ Breast cancer cells use a molecular switch to survive stress #Acetylation #BreastCancer #cancer #Cell #CellCulture #Éire #estrogen #Gene #GeneExpression #Genes #Genetic #IE #Ireland #Protein #Receptor #Research #RNA #Science #Stress #Transcription #Tumor
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This allows condensate behaviour to respond to different inputs, such as lysine #acetylation in IDRs in other CBP domains. It can help to explain how #transcription factors binding to different regions of CBP differentially regulate CBP activity. #enhancers #generegulation #llps #chromatin #imaging #biochemistry #molecularbiology #CellBiology
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This allows condensate behaviour to respond to different inputs, such as lysine #acetylation in IDRs in other CBP domains. It can help to explain how #transcription factors binding to different regions of CBP differentially regulate CBP activity. #enhancers #generegulation #llps #chromatin #imaging #biochemistry #molecularbiology #CellBiology
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This allows condensate behaviour to respond to different inputs, such as lysine #acetylation in IDRs in other CBP domains. It can help to explain how #transcription factors binding to different regions of CBP differentially regulate CBP activity. #enhancers #generegulation #llps #chromatin #imaging #biochemistry #molecularbiology #CellBiology
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This allows condensate behaviour to respond to different inputs, such as lysine #acetylation in IDRs in other CBP domains. It can help to explain how #transcription factors binding to different regions of CBP differentially regulate CBP activity. #enhancers #generegulation #llps #chromatin #imaging #biochemistry #molecularbiology #CellBiology
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This allows condensate behaviour to respond to different inputs, such as lysine #acetylation in IDRs in other CBP domains. It can help to explain how #transcription factors binding to different regions of CBP differentially regulate CBP activity. #enhancers #generegulation #llps #chromatin #imaging #biochemistry #molecularbiology #CellBiology
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Researchers reveal how #acetylation regulates #centromere dynamics, #chromosome #segregation and #mitotic progression.
https://phys.org/news/2024-05-reveal-acetylation-centromere-dynamics-chromosome.html
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Researchers reveal how #acetylation regulates #centromere dynamics, #chromosome #segregation and #mitotic progression.
https://phys.org/news/2024-05-reveal-acetylation-centromere-dynamics-chromosome.html
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Researchers reveal how #acetylation regulates #centromere dynamics, #chromosome #segregation and #mitotic progression.
https://phys.org/news/2024-05-reveal-acetylation-centromere-dynamics-chromosome.html
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Researchers reveal how #acetylation regulates #centromere dynamics, #chromosome #segregation and #mitotic progression.
https://phys.org/news/2024-05-reveal-acetylation-centromere-dynamics-chromosome.html
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Researchers reveal how #acetylation regulates #centromere dynamics, #chromosome #segregation and #mitotic progression.
https://phys.org/news/2024-05-reveal-acetylation-centromere-dynamics-chromosome.html
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The cell's 'read–write' mechanism: Researchers uncover how instructions for #gene #expression are relayed.
#Epigenetic #histone #p300_CBP #acetylation
https://phys.org/news/2023-11-cell-readwrite-mechanism-uncover-gene.html
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The cell's 'read–write' mechanism: Researchers uncover how instructions for #gene #expression are relayed.
#Epigenetic #histone #p300_CBP #acetylation
https://phys.org/news/2023-11-cell-readwrite-mechanism-uncover-gene.html
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"CD8+ Teff cells preferentially used #ketone bodies (KBs) over #glucose to fuel the tricarboxylic acid (TCA) cycle in vitro and in vivo. KBs directly boosted the respiratory capacity and TCA cycle-dependent metabolic pathways that fuel CD8+ T cell function. Mechanistically, βOHB was a major substrate for acetyl-CoA production in CD8+ T cells and regulated effector responses through effects on #histone #acetylation"
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"CD8+ Teff cells preferentially used #ketone bodies (KBs) over #glucose to fuel the tricarboxylic acid (TCA) cycle in vitro and in vivo. KBs directly boosted the respiratory capacity and TCA cycle-dependent metabolic pathways that fuel CD8+ T cell function. Mechanistically, βOHB was a major substrate for acetyl-CoA production in CD8+ T cells and regulated effector responses through effects on #histone #acetylation"
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"CD8+ Teff cells preferentially used #ketone bodies (KBs) over #glucose to fuel the tricarboxylic acid (TCA) cycle in vitro and in vivo. KBs directly boosted the respiratory capacity and TCA cycle-dependent metabolic pathways that fuel CD8+ T cell function. Mechanistically, βOHB was a major substrate for acetyl-CoA production in CD8+ T cells and regulated effector responses through effects on #histone #acetylation"
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"CD8+ Teff cells preferentially used #ketone bodies (KBs) over #glucose to fuel the tricarboxylic acid (TCA) cycle in vitro and in vivo. KBs directly boosted the respiratory capacity and TCA cycle-dependent metabolic pathways that fuel CD8+ T cell function. Mechanistically, βOHB was a major substrate for acetyl-CoA production in CD8+ T cells and regulated effector responses through effects on #histone #acetylation"
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How does #centrosome #amplification -common in #cancer- promote #cellmigration through confined spaces?
Susana Godinho and colleagues show that it alters intracellular organization via effects on #tubulin #acetylation and #organelle transport along #microtubules
https://www.embopress.org/doi/full/10.15252/embj.2022112812 -
How does #centrosome #amplification -common in #cancer- promote #cellmigration through confined spaces?
Susana Godinho and colleagues show that it alters intracellular organization via effects on #tubulin #acetylation and #organelle transport along #microtubules
https://www.embopress.org/doi/full/10.15252/embj.2022112812 -
How does #centrosome #amplification -common in #cancer- promote #cellmigration through confined spaces?
Susana Godinho and colleagues show that it alters intracellular organization via effects on #tubulin #acetylation and #organelle transport along #microtubules
https://www.embopress.org/doi/full/10.15252/embj.2022112812 -
How does #centrosome #amplification -common in #cancer- promote #cellmigration through confined spaces?
Susana Godinho and colleagues show that it alters intracellular organization via effects on #tubulin #acetylation and #organelle transport along #microtubules
https://www.embopress.org/doi/full/10.15252/embj.2022112812 -
How does #centrosome #amplification -common in #cancer- promote #cellmigration through confined spaces?
Susana Godinho and colleagues show that it alters intracellular organization via effects on #tubulin #acetylation and #organelle transport along #microtubules
https://www.embopress.org/doi/full/10.15252/embj.2022112812 -
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#Structural insights into p300 regulation and #acetylation-dependent genome organisation
https://www.nature.com/articles/s41467-022-35375-2- #alphafold model of p300 suggests that the TAZ2 domain is positioned over the p300 HAT active site
- #alphafold model in the presence of NUT AD shows that the TAZ2 domain is displaced from the HAT active site and suggest that the TAZ2 domain auto-inhibits the HAT domain
- domain truncation and #mutagenesis support the #computational #models !
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😱
#Structural insights into p300 regulation and #acetylation-dependent genome organisation
https://www.nature.com/articles/s41467-022-35375-2- #alphafold model of p300 suggests that the TAZ2 domain is positioned over the p300 HAT active site
- #alphafold model in the presence of NUT AD shows that the TAZ2 domain is displaced from the HAT active site and suggest that the TAZ2 domain auto-inhibits the HAT domain
- domain truncation and #mutagenesis support the #computational #models !
-
😱
#Structural insights into p300 regulation and #acetylation-dependent genome organisation
https://www.nature.com/articles/s41467-022-35375-2- #alphafold model of p300 suggests that the TAZ2 domain is positioned over the p300 HAT active site
- #alphafold model in the presence of NUT AD shows that the TAZ2 domain is displaced from the HAT active site and suggest that the TAZ2 domain auto-inhibits the HAT domain
- domain truncation and #mutagenesis support the #computational #models !
-
😱
#Structural insights into p300 regulation and #acetylation-dependent genome organisation
https://www.nature.com/articles/s41467-022-35375-2- #alphafold model of p300 suggests that the TAZ2 domain is positioned over the p300 HAT active site
- #alphafold model in the presence of NUT AD shows that the TAZ2 domain is displaced from the HAT active site and suggest that the TAZ2 domain auto-inhibits the HAT domain
- domain truncation and #mutagenesis support the #computational #models !
-
😱
#Structural insights into p300 regulation and #acetylation-dependent genome organisation
https://www.nature.com/articles/s41467-022-35375-2- #alphafold model of p300 suggests that the TAZ2 domain is positioned over the p300 HAT active site
- #alphafold model in the presence of NUT AD shows that the TAZ2 domain is displaced from the HAT active site and suggest that the TAZ2 domain auto-inhibits the HAT domain
- domain truncation and #mutagenesis support the #computational #models !