A synthetic benzothiazole-thiourea derivative with multi-target potential activity for Alzheimer's disease: Antioxidant properties and mechanistic insights.
Neuropharmacology. 2026 Sep 25;301:111199. Epub 2026 Sep 25Authors: Lahouel A, Harrouche K, Oguz E, Türkan F, Cetin A, Khelili SPubMed: 42790732Submit Comment
Read more: https://www.alzforum.org/papers/synthetic-benzothiazole-thiourea-derivative-multi-target-potential-activity-alzheimers
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Activation of TREM2 via single-domain antibodies improves synaptic and cognitive function in 5×FAD mice.
Cell Rep. 2026 Sep 26;45(10):118063. Epub 2026 Sep 26Authors: Yu X, Ren Q, Gao Y, Xie S, Dang R, Meng J, Su Z, Li M, Ao Y, Liu A, Wang Y, Xie WPubMed: 42800026Submit Comment
Read more: https://www.alzforum.org/papers/activation-trem2-single-domain-antibodies-improves-synaptic-and-cognitive-function-5xfad-mice
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Integrating transcriptomic data to identify calmodulin-related diagnostic biomarkers for Alzheimer's disease.
J Alzheimers Dis. 2026 Sep 28;:13872877261487604. Epub 2026 Sep 28Authors: Wang X, Huang Y, Li JPubMed: 42803726Submit Comment
Read more: https://www.alzforum.org/papers/integrating-transcriptomic-data-identify-calmodulin-related-diagnostic-biomarkers-alzheimers
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Tau Overexpression Causes Cardiac Hypertrophy by Disrupting Mitochondrial Homeostasis.
Int J Mol Sci. 2026 Sep 11;27(18)Authors: Xu J, Xing Y, Liu Q, Wang T, Liu W, Yang X, Li Z, Wang JPubMed: 42794506Submit Comment
Read more: https://www.alzforum.org/papers/tau-overexpression-causes-cardiac-hypertrophy-disrupting-mitochondrial-homeostasis
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Interpreting Viral Associations in Neurodegenerative Diseases.
Int J Mol Sci. 2026 Sep 15;27(18)Authors: Hedström AKPubMed: 42794615Submit Comment
Read more: https://www.alzforum.org/papers/interpreting-viral-associations-neurodegenerative-diseases
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Mast Cells in Neuroimmune Interactions: Mechanisms, Pathophysiological Roles, and Therapeutic Implications.
Mol Neurobiol. 2026 Sep 26;63(1)Authors: Hasan A, Asfour AA, Qaba H, Al-Sharabi AA, Asfoor A, Mohammed S, Al-Adhreai A, Güner S, ALSaeedy MPubMed: 42799832Submit Comment
Read more: https://www.alzforum.org/papers/mast-cells-neuroimmune-interactions-mechanisms-pathophysiological-roles-and-therapeutic
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Neuroinflammation and metabolic reprogramming in Parkinson's disease.
Front Immunol. 2026;17:1857394. Epub 2026 Sep 11Authors: Fu Y, Yu J, Xu L, Zhou T, Deng QPubMed: 42798987Submit Comment
Read more: https://www.alzforum.org/papers/neuroinflammation-and-metabolic-reprogramming-parkinsons-disease
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Altered temporal features of visual processing in subjective cognitive decline.
Neuropsychology. 2026 Oct 1; Epub 2026 Oct 1Authors: Lévesque M, Akzam-Ouellette MA, Joubert S, Arguin MPubMed: 42821427Submit Comment
Read more: https://www.alzforum.org/papers/altered-temporal-features-visual-processing-subjective-cognitive-decline
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Cinnamic Acid-based Hybrid Molecules as Multitarget Therapeutic Agents for Cancer, Alzheimer's Disease, and Malaria: A Review.
Mini Rev Med Chem. 2026 Sep 28; Epub 2026 Sep 28Authors: Anshika, Tailor NKPubMed: 42816978Submit Comment
Read more: https://www.alzforum.org/papers/cinnamic-acid-based-hybrid-molecules-multitarget-therapeutic-agents-cancer-alzheimers-disease
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The brain's immune code: decoding antigen presentation at the meningeal-glymphatic interface in neurological disorders.
Front Immunol. 2026;17:1960846. Epub 2026 Sep 15Authors: Li W, Liang Y, Li L, Sun H, Liu QPubMed: 42813059Submit Comment
Read more: https://www.alzforum.org/papers/brains-immune-code-decoding-antigen-presentation-meningeal-glymphatic-interface-neurological
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Oleandrin and PBI-05204 for Neuroprotection in Alzheimer's Disease, Parkinson's Disease, and Stroke: Preclinical Mechanisms, Blood-brain Barrier Penetration, and Clinical Translation Perspectives.
Mini Rev Med Chem. 2026 Sep 28; Epub 2026 Sep 28Authors: Pal T, Singh PPubMed: 42816980Submit Comment
Read more: https://www.alzforum.org/papers/oleandrin-and-pbi-05204-neuroprotection-alzheimers-disease-parkinsons-disease-and-stroke
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Perspectives from Alzheimer's Disease Research Centers site directors on the early steps and the lasting impact.
Alzheimers Dement. 2026 Oct;22(10):e71694. Authors: Growdon JH, Morris JC, Petersen RC, Sano M, Schneider LSPubMed: 42805939Submit Comment
Read more: https://www.alzforum.org/papers/perspectives-alzheimers-disease-research-centers-site-directors-early-steps-and-lasting
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Molecular Details of RNA Interactions With FUS Condensates Altering Assembly, Dynamics, and Aggregation.
Angew Chem Int Ed Engl. 2026 Sep 25;:e1070299. Epub 2026 Sep 25Authors: Zheng T, Sojitra KA, Cummings S, Chen Q, Mohanty P, Mittal J, Fawzi NLPubMed: 42788291Submit Comment
Read more: https://www.alzforum.org/papers/molecular-details-rna-interactions-fus-condensates-altering-assembly-dynamics-and-aggregation
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Targeting CH25H restores p62-mediated α-synuclein clearance.
Trends Pharmacol Sci. 2026 Sep 28; Epub 2026 Sep 28Authors: Dawe GSPubMed: 42805814Submit Comment
Read more: https://www.alzforum.org/papers/targeting-ch25h-restores-p62-mediated-synuclein-clearance
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Reader Response: Midlife Vascular Risk Factors, Parkinson Disease, and Parkinson Disease-Dementia: The ARIC Study.
Neurology. 2026 Oct 27;107(8):e214854. Epub 2026 Sep 25Authors: Adhya A, Tripathi M, Elavarasi A, Vetal DPubMed: 42789820Submit Comment
Read more: https://www.alzforum.org/papers/reader-response-midlife-vascular-risk-factors-parkinson-disease-and-parkinson-disease
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A coordinated multi-target approach based on chondroitin sulphate nano-selenium mitigates Alzheimer's disease pathologies in APP/PS1 mice.
Front Pharmacol. 2026;17:1936198. Epub 2026 Sep 15Authors: Ji D, Zhao J, Huang X, Liu X, Yang Q, Li X, Yan L, Gao D, Xiao YPubMed: 42812304Submit Comment
Read more: https://www.alzforum.org/papers/coordinated-multi-target-approach-based-chondroitin-sulphate-nano-selenium-mitigates
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α-Synuclein Pathology in Idiopathic Normal Pressure Hydrocephalus: Evidence for Concomitant Synucleinopathy and Clinical Implications.
Diagnostics (Basel). 2026 Sep 8;16(18)Authors: Pyrgelis ES, Paraskevas GP, Constantinides VC, Boufidou F, Stefanis L, Kapaki EPubMed: 42793674Submit Comment
Read more: https://www.alzforum.org/papers/synuclein-pathology-idiopathic-normal-pressure-hydrocephalus-evidence-concomitant
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Non-invasive neuromodulation in Alzheimer's disease: toward brain-heart coupling as a candidate framework for biomarker-guided adaptive intervention.
Rev Neurosci. 2026 Oct 2; Epub 2026 Oct 2Authors: Zheng W, Ma Y, Su C, Qiu Z, Yan Z, Xu G, Geng D, Wang APubMed: 42817879Submit Comment
Read more: https://www.alzforum.org/papers/non-invasive-neuromodulation-alzheimers-disease-toward-brain-heart-coupling-candidate
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Dorsal and ventral stream visuoperceptual processing deficits in Lewy body disease.
J Neurol. 2026 Sep 25;273(10)Authors: McCann E, Coleman F, Lee S, Fazlollahi A, O'Sullivan JD, Nestor PJPubMed: 42789112Submit Comment
Read more: https://www.alzforum.org/papers/dorsal-and-ventral-stream-visuoperceptual-processing-deficits-lewy-body-disease
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