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#upf2 — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #upf2, aggregated by home.social.

  1. Cosmin Saveanu @[email protected] ·

    Nonsense mediated mRNA decay (#NMD) is frequently a target of viral proteins since an active NMD can limit viral replication. As shown by the lovely work of Fiorini and colleagues, the N protein of #SARS-CoV-2 physically and functionally interact with #Upf1 and #Upf2, two core NMD factors. These results complement previously published studies, such as the one from the Makino group, 2018, on the murine hepatitis virus, a related coronavirus.

    pubmed.ncbi.nlm.nih.gov/398313
    pubmed.ncbi.nlm.nih.gov/302974

    #rna

    #nmd #sars #upf1 #upf2 #rna