#morphogen — Public Fediverse posts

A thoughtful review on how Dpp/BMP functions as a #morphogen in the #Drosophila wing to control growth and patterning. There is still much to learn!
#DevBio
https://doi.org/10.1002/bies.202200218

Our paper builds on previous work from our group that

- introduced the 1D morphogen gradient model:
https://twitter.com/DagmarIber/status/1499631526056796162

- revealed the impact of cell size on patterning precision:
https://twitter.com/DagmarIber/status/1489479705292156933

- explored the effect of non-linear decay:

---
RT @DagmarIber
Does self-enhanced #morphogen #degradation improve #patterning #precision in #tissue #development? …
https://twitter.com/DagmarIber/status/1589511772285054976

Our paper builds on previous work from our group that

- introduced the 1D morphogen gradient model:
https://twitter.com/DagmarIber/status/1499631526056796162

- revealed the impact of cell size on patterning precision:
https://twitter.com/DagmarIber/status/1489479705292156933

- explored the effect of non-linear decay:

---
RT @DagmarIber
Does self-enhanced #morphogen #degradation improve #patterning #precision in #tissue #development? …
https://twitter.com/DagmarIber/status/1589511772285054976

Our paper builds on previous work from our group that

- introduced the 1D morphogen gradient model:
https://twitter.com/DagmarIber/status/1499631526056796162

- revealed the impact of cell size on patterning precision:
https://twitter.com/DagmarIber/status/1489479705292156933

- explored the effect of non-linear decay:

---
RT @DagmarIber
Does self-enhanced #morphogen #degradation improve #patterning #precision in #tissue #development? …
https://twitter.com/DagmarIber/status/1589511772285054976

The #positional #error of a #morphogen #gradient significantly decreases as the patterned #tissue widens. It can drop from above one #cell diameter to below half a cell diameter, before saturating at a #tissue width beyond about 10 cells.

How to achieve high #patterning #precision in #development?

#Morphogen gradients are more precise in #2D than in 1D, in particular when #cells are #narrow.

Check out our latest #preprint on @biorxivpreprint: https://doi.org/10.1101/2023.03.13.532369

How to achieve high #patterning #precision in #development?

#Morphogen gradients are more precise in #2D than in 1D, in particular when #cells are #narrow.

Check out our latest #preprint on @biorxivpreprint: https://doi.org/10.1101/2023.03.13.532369

How to achieve high #patterning #precision in #development?

#Morphogen gradients are more precise in #2D than in 1D, in particular when #cells are #narrow.

Check out our latest #preprint on @biorxivpreprint: https://doi.org/10.1101/2023.03.13.532369

How to achieve high #patterning #precision in #development?

#Morphogen gradients are more precise in #2D than in 1D, in particular when #cells are #narrow.

Check out our latest #preprint on @biorxivpreprint: https://doi.org/10.1101/2023.03.13.532369

Study shows that morphogens in #Drosophila blastoderm control formation of cell densities along the #DVaxis that in turn is necessary for fine-tuning #morphogen gradient levels; #frazzled & #GUKholder are key effectors in this process #PLOSBiology https://plos.io/3YKufMO

Study shows that morphogens in #Drosophila blastoderm control formation of cell densities along the #DVaxis that in turn is necessary for fine-tuning #morphogen gradient levels; #frazzled & #GUKholder are key effectors in this process #PLOSBiology https://plos.io/3YKufMO

Study shows that morphogens in #Drosophila blastoderm control formation of cell densities along the #DVaxis that in turn is necessary for fine-tuning #morphogen gradient levels; #frazzled & #GUKholder are key effectors in this process #PLOSBiology https://plos.io/3YKufMO

Hi everyone!

The Vincent lab twitter account completes its migration to Mastodon.
Follow us for cool #DevBio science, mostly working with #Drosophila. We are generally interested in the signalling activities that control patterning, growth and apoptosis in epithelia. Our #morphogen of choice is #Wnt.

Here you may also find the occasional rant from JP once he gets used to the new format. Until then, this account is mostly managed by postdoc Ines.