#medstatgoe — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #medstatgoe, aggregated by home.social.
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📢 Our next #DFG -funded symposium on
"Recent advances in #MetaAnalysis"
will be taking place May 28/29 in Göttingen.
For more details, see here:
➡️ https://medstat.umg.eu/aktuelles/symposium-meta-analysis-2026/
and stay tuned for updates! -
🤔 Meta-analyses considering differences between subgroups within each study ("treatment-by-subgroup interactions") do not necessarily yield matching estimates for effects within subgroups and the difference between them.
💡 @panaro worked out how explicit consideration of information fractions contributed by subgroups in the analysis model allows to fix this counterintuitive behaviour; see here for details:
➡️ https://arxiv.org/abs/2512.18785
(joint work with @friede1). -
🤔 Estimation of between-study variability (heterogeneity) is tricky when only few studies are available.
❓ Can we make use of additional information, by considering subgroups within studies?
💡 It turns out we can -- yielding better performance due to fewer zero-estimates and more degrees-of-freedom.
👉 See here: https://arxiv.org/abs/2511.15366
(Joint work with Ao Huang and @friede1 ) -
📢 A mini-symposium on "Adaptive Designs - Modern Approaches in Clinical Research" will be held in Göttingen next February.
See here for more details:
👉 https://medstat.umg.eu/en/events/ -
📢 A mini-symposium on "Adaptive Designs - Modern Approaches in Clinical Research" will be held in Göttingen next February.
See here for more details:
👉 https://medstat.umg.eu/en/events/ -
📢 A mini-symposium on "Adaptive Designs - Modern Approaches in Clinical Research" will be held in Göttingen next February.
See here for more details:
👉 https://medstat.umg.eu/en/events/ -
Meta-analyses comparing treatment effects in patient subgroups (e.g. males vs. females) may be tricky, and may in fact sometimes suggest contradictory findings. Renato Panaro (@panaro) looked at the mechanisms at work, and also suggests a possible solution:
👉 https://arxiv.org/abs/2508.15531
(joint work with @friede1). -
Our Dortmund colleagues hosted an inspiring symposium last week within our #DFG -funded project on "Valid methods for meta-analyses with few studies and small sample sizes"; see here for details:
👉 https://msind.statistik.tu-dortmund.de/en/research/events/meta-analysis-symposium-2025
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Most #MetaAnalysis approaches are based on parametric models, which may be challenging in case of sparse data (few / small studies). Thien Phuc Tran and Long-Hao Xu have developed a nonparametric permutation approach for #MetaAnalysis based on individual participant data (IPD); see here for details:
👉 https://arxiv.org/abs/2505.24774 -
🤔 Should one meta-analyze a single study?
☝️🤓 It turns out this makes sense in certain cases - if you're looking for predictions ("MAP priors"). In the particular case of a single study, there are also close links to power priors and bias allowance models. Have a look:
➡️ https://arxiv.org/abs/2505.15502
(joint work with @friede1 ) -
A very interesting workshop on "Hierarchical models in preclinical research" finished today in Göttingen. This was a joint undertaking of the IBS-DR working groups "Non-clinical statistics" and "Bayes Methods", and included an extensive Tutorial on #brms by Sebastian Weber and Lukas Widmer. Some of the material is available on the meeting website:
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The EU-funded 🇪🇺 INVENTS project (https://invents-he.eu) held its first annual consortium meeting this week in Göttingen. Looking forward to further fruitful collaboration!
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The working groups "Bayes Methods" and "Non-Clinical Statistics" of the International Biometric Society's German Region (IBS-DR) are organizing a workshop on
➡️ HIERARCHICAL MODELS IN PRECLINICAL RESEARCH
on December 5-6 in Göttingen.
Meanwhile the PROGRAM is available, and REGISTRATION is still possible -- see here for more details:
➡️ https://www.biometrische-gesellschaft.de/arbeitsgruppen/bayes-methodik/workshops/2024-goettingen.html -
A kick-off meeting of researchers from Japan and Germany within the #HeKKSaGOn network (www.HeKKSaGOn.net) came to a successful finish today in Göttingen. Looking forward to further collaborations!
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Clinical trials are usually designed to demonstrate an overall treatment effect, but are often not able to resolve effects in patient subgroups. We performed a #MetaAnalysis, considering several studies to look for differences in treatment effects between patient subgroups in #MultipleSclerosis and investigate which patients may benefit most (or least) from immunotherapy. See here for more details:
➡️ https://doi.org/10.1177/20552173241274618 -
The working groups "Bayes Methods" and "Non-Clinical Statistics" of the International Biometric Society's German Region (IBS-DR) are organizing a workshop on
➡️ HIERARCHICAL MODELS IN PRECLINICAL RESEARCH
on December 5-6 in Göttingen.
See here for more details:
➡️ https://www.biometrische-gesellschaft.de/arbeitsgruppen/bayes-methodik/workshops/2024-goettingen.html -
We hosted a meeting on "Recent advances in #MetaAnalysis" two weeks ago here in Göttingen. Presentation slides and posters are now available on our website:
➡️ https://medstat.umg.eu/aktuelles/symposium-meta-analysis-2024/
#MedStatGoe -
🤔 If you do two replications of a study, will the results "look similar"❓
How easy is it to tell from just a pair of estimates whether results are "homogeneous"❓
We had a closer look at this case; the publication just appeared:
➡️ https://doi.org/10.1002/bimj.202300387
(joint work with @friede1 )
#MetaAnalysis #MedStatGoe -
A successful symposium on "Recent advances in #MetaAnalysis" finished today. Abstracts and presentations will soon be available on our website:
https://medstat.umg.eu/aktuelles/symposium-meta-analysis-2024/
Looking forward to another symposium next year...
#MedStatGoe