#circadian — Public Fediverse posts

The clockwork macrophage: Timing in #innateimmunity

(free review article)

#OpenAccess #circadian #immunity

https://davidojcius.blogspot.com/2026/05/the-clockwork-macrophage-timing-in.html

📰 "The interplay of insulin signaling and neurotransmitters on sleep in Drosophila"
https://doi.org/doi:10.1016/j.yfrne.2026.101252
https://pubmed.ncbi.nlm.nih.gov/42102933/
#DrosophilaMelanogaster
#Circadian
#Metabolism #Drosophila #Sleep

📰 "Bidirectional regulation between circadian feeding behavior and specialized midgut clocks in Drosophila"
https://doi.org/doi:10.64898/2026.04.23.720414
https://pubmed.ncbi.nlm.nih.gov/42094398/
#Metabolism #Circadian
#Drosophila #Behaviour

📰 "Bidirectional regulation between circadian feeding behavior and specialized midgut clocks in Drosophila"
https://doi.org/doi:10.64898/2026.04.23.720414
https://pubmed.ncbi.nlm.nih.gov/42094398/
#Metabolism #Circadian
#Drosophila #Behaviour

📰 "Bidirectional regulation between circadian feeding behavior and specialized midgut clocks in Drosophila"
https://doi.org/doi:10.64898/2026.04.23.720414
https://pubmed.ncbi.nlm.nih.gov/42094398/
#Metabolism #Circadian
#Drosophila #Behaviour

☀️⏰ #Research shows that permanent daylight saving time causes darker mornings that interfere with our natural #circadian rhythms. This misalignment is linked to higher rates of #cardiovascular #disease and metabolic #health issues in the general population.

👉 https://www.popsci.com/science/permanent-daylight-saving-time-video/

#biology #science #sleep #dst #wellness #medicine #metabolism #physiology

☀️⏰ #Research shows that permanent daylight saving time causes darker mornings that interfere with our natural #circadian rhythms. This misalignment is linked to higher rates of #cardiovascular #disease and metabolic #health issues in the general population.

👉 https://www.popsci.com/science/permanent-daylight-saving-time-video/

#biology #science #sleep #dst #wellness #medicine #metabolism #physiology

☀️⏰ #Research shows that permanent daylight saving time causes darker mornings that interfere with our natural #circadian rhythms. This misalignment is linked to higher rates of #cardiovascular #disease and metabolic #health issues in the general population.

👉 https://www.popsci.com/science/permanent-daylight-saving-time-video/

#biology #science #sleep #dst #wellness #medicine #metabolism #physiology

☀️⏰ #Research shows that permanent daylight saving time causes darker mornings that interfere with our natural #circadian rhythms. This misalignment is linked to higher rates of #cardiovascular #disease and metabolic #health issues in the general population.

👉 https://www.popsci.com/science/permanent-daylight-saving-time-video/

#biology #science #sleep #dst #wellness #medicine #metabolism #physiology

☀️⏰ #Research shows that permanent daylight saving time causes darker mornings that interfere with our natural #circadian rhythms. This misalignment is linked to higher rates of #cardiovascular #disease and metabolic #health issues in the general population.

👉 https://www.popsci.com/science/permanent-daylight-saving-time-video/

#biology #science #sleep #dst #wellness #medicine #metabolism #physiology

📰 "Molecular foundations and tissue-specific dynamics of the mosquito circadian clock"
https://doi.org/doi:10.1016/j.pt.2026.04.003
https://pubmed.ncbi.nlm.nih.gov/42069471/
#Drosophila #Circadian

📰 "YIPPEE/YPEL5 regulates circadian period by modulating PER ubiquitination and stability"
https://www.biorxiv.org/content/10.64898/2026.04.28.721296v1?rss=1
#Drosophila #Circadian
#Behaviour

📰 "Microbe-dependent inter-organ communication regulates germline stem cell proliferation in Drosophila"
https://www.biorxiv.org/content/10.64898/2026.04.27.717131v1?rss=1
#DrosophilaMelanogaster
#Metabolism #Circadian
#Drosophila

📰 "Disrupting the clock of the Madeira cockroach through RNAi-mediated knockdown of CLOCK and CYCLE"
https://www.biorxiv.org/content/10.64898/2026.04.27.720303v1?rss=1
#Drosophila #Circadian
#Behaviour

🌙🧠 #Research suggests that the human #brain is biologically predisposed to negative emotions and increased impulsivity during late night hours.

The phenomenon occurs because the internal #circadian clock naturally shifts toward lower mood and reduced cognitive control after midnight. Scientists explain that these biological changes evolved for #sleep and can lead to distorted thinking when #people remain awake.

👉 https://www.zmescience.com/science/news-science/why-everything-really-does-feel-worse-at-midnight-but-better-in-the-morning/

#biology #psychology #science #health #mentalhealth

📰 "Bidirectional regulation between circadian feeding behavior and specialized midgut clocks in Drosophila"
https://www.biorxiv.org/content/10.64898/2026.04.23.720414v1?rss=1
#Metabolism #Circadian
#Drosophila #Behaviour

The #circadian clock & cellular #metabolism are tightly coupled. This Primer explores a @plosbiology.org study showing how #glucose metabolism changes during the day in #Drosophila and how it is disrupted in clock & sleep mutants. Paper: https://plos.io/3Olm1M1 Primer: https://plos.io/4sUov2g

📰 "Circadian clock gates diurnal glucose utilization"
https://doi.org/doi:10.1371/journal.pbio.3003743
https://pubmed.ncbi.nlm.nih.gov/41996297/
#Circadian
#Metabolism #Drosophila #Sleep

📰 "Glucose is dynamically regulated by time of day in humans and Drosophila"
https://doi.org/doi:10.1371/journal.pbio.3003717
https://pubmed.ncbi.nlm.nih.gov/41989995/
#Circadian
#Metabolism #Drosophila

How do #circadian clocks regulate glucose processing? By integrating human metabolite profiling with isotope-tracing in #Drosophila, this study defines daily rhythms in #glucose utilization that are influenced by circadian timing @PLOSBiology https://plos.io/3Olm1M1

Does the mammalian #circadian clock manage to temperature-compensate during deep #hypothermia? This study shows that mice maintain circadian rhythms during a #hibernation -like hypothermic state, and that this is supported by systemic regulatory mechanisms @PLOSBiology https://plos.io/4tW1pJt

📰 "The curious case of CCHamide1: a role for CCHamide1 in sleep, metabolism and fitness in Drosophila melanogaster"
https://doi.org/doi:10.1093/genetics/iyag096
https://pubmed.ncbi.nlm.nih.gov/41968725/
#DrosophilaMelanogaster
#Drosophila #Metabolism #Circadian
#Sleep

📰 "Drosophila RSK: A Pivotal Regulator of Circadian Plasticity at the Neuronal and Behavioral Level"
https://doi.org/doi:10.1177/07487304261434715
https://pubmed.ncbi.nlm.nih.gov/41966995/
#Circadian
#Drosophila #Behaviour

📰 "Cell-type-specific circadian and light-responsive transcriptional dynamics in adult Drosophila neurons"
https://www.biorxiv.org/content/10.64898/2026.04.07.717038v1?rss=1
#Circadian
#Drosophila #Behaviour #Adult

📰 "Circadian Rhythms Time Seizure Severity in Drosophila"
https://doi.org/doi:10.1177/07487304261428337
https://pubmed.ncbi.nlm.nih.gov/41958013/
#DrosophilaMelanogaster
#Drosophila #Circadian

📰 "Metaplastic sleep regulation in Drosophila determined by microscale circadian neural dynamics"
https://doi.org/doi:10.64898/2026.03.21.713346
https://pubmed.ncbi.nlm.nih.gov/41929078/
#Drosophila #Circadian
#Sleep

https://www.theguardian.com/science/2026/apr/05/satellite-mirror-plans-could-disrupt-sleep-and-ecosystems-worldwide-scientists-say; https://www.bioclocks.uk/news/bambos-. "Proposals to deploy reflective #mirrors & up to 1m more #satellites in low #Earth #orbit could have far-reaching #consequences for #human #health & #ecosystems, leading #sleep & #circadian #rhythm #researchers have said."

📰 "Inferring circadian phases and quantifying biological desynchrony across single-cell transcriptomes"
https://www.biorxiv.org/content/10.64898/2026.03.30.715278v1?rss=1
#Circadian
#Drosophila

📰 "Metaplastic sleep regulation in Drosophila determined by microscale circadian neural dynamics"
https://www.biorxiv.org/content/10.64898/2026.03.21.713346v1?rss=1
#Drosophila #Circadian
#Sleep

📰 "Drosophila core circadian clock neurons peptidergically regulate activity of insulin-producing cells"
https://www.biorxiv.org/content/10.64898/2026.03.23.713581v1?rss=1
#Drosophila #Circadian

📰 "Brain Transcriptomics Across Diverse Sleep-Wake Manipulations Reveals Multiple Homeostatic Pathways in Drosophila"
https://doi.org/doi:10.64898/2026.02.28.708752
https://pubmed.ncbi.nlm.nih.gov/41867706/
#Circadian
#Drosophila #Sleep

📰 "Assessment of adult structural plasticity in Drosophila neurons"
https://www.biorxiv.org/content/10.64898/2026.03.11.711108v1?rss=1
#Circadian
#Drosophila #Adult

Our colleagues in the #Circadian Mental Health Network comment on a research study in Trondheim 🇳🇴, by @lindageddes today in @TheGuardian:

⏬ lowering the blue light in an inpatient psychiatric ward improved the quality of treatment.

https://www.theguardian.com/science/2026/mar/13/how-the-colour-of-light-could-be-used-to-treat-mental-illness-norway

#mentalhealth #research #architecture #lighting

🌱 Flowers open, forests shift, and ancient trees move through their days with a quiet sense of rhythm. What if plants keep time more subtly than our clocks?

✍️ Explore the quiet clocks of plant life: https://TPC8.short.gy/3qxzQGl1

A different kind of timekeeping waits beneath each leaf.

#Plants #Science #Circadian #Biology #Phenology #Nature #Botany #TPC8

📰 "A day sleep promoting role of phototransduction in Drosophila melanogaster"
https://doi.org/doi:10.1016/j.nbscr.2026.100146
https://pubmed.ncbi.nlm.nih.gov/41815955/
#DrosophilaMelanogaster
#Circadian
#Drosophila #Behaviour #Sensory
#Sleep

Mornin' #circadian research folk, I believe I see a new way to get to #Padua for the next #EBRS meeting! 👀🚄🏴󠁧󠁢󠁳󠁣󠁴󠁿🇮🇹
OK looks like this service is also waiting to escape vintage carriages...

https://fed.brid.gy/r/https://bsky.app/profile/did:plc:vth6nor3jyocbspcnp7ckmcp/post/3mg57oulzi22r

#StayGrounded #FlyingLess

📰 "Sleep regulation in Drosophila: a review of neural circuits and genetics"
https://doi.org/doi:10.3389/fnins.2026.1750211
https://pubmed.ncbi.nlm.nih.gov/41705129/
#DrosophilaMelanogaster
#InternalState
#Circadian
#Drosophila #Sleep

📰 "Sleep regulation in Drosophila: a review of neural circuits and genetics"
https://doi.org/doi:10.3389/fnins.2026.1750211
https://pubmed.ncbi.nlm.nih.gov/41705129/
#DrosophilaMelanogaster
#InternalState
#Circadian
#Drosophila #Sleep

📰 "Sleep regulation in Drosophila: a review of neural circuits and genetics"
https://doi.org/doi:10.3389/fnins.2026.1750211
https://pubmed.ncbi.nlm.nih.gov/41705129/
#DrosophilaMelanogaster
#InternalState
#Circadian
#Drosophila #Sleep

📰 "Sleep regulation in Drosophila: a review of neural circuits and genetics"
https://doi.org/doi:10.3389/fnins.2026.1750211
https://pubmed.ncbi.nlm.nih.gov/41705129/
#DrosophilaMelanogaster
#InternalState
#Circadian
#Drosophila #Sleep

Researchers reproduced the simplest natural #circadian system found in blue-green algae (#cyanobacteria ) within a test tube, demonstrating how a single clock signal coordinates daily #gene switching.
#MolecularBiology #Biotechnology #Chronobiology #sflorg
https://www.sflorg.com/2026/02/mbio02102601.html

📢 Looking forward to my return visit to Norwich and the @earlhaminst, this time to give the Dame Janet Thornton lecture on Thursday 13th.

Register link (with reception afterwards 🍰, do come and say hello!):
➡️ https://www.earlham.ac.uk/events/dame-janet-thornton-annual-lecture-2025

As well as talking #circadian clocks in #plantsci 🌿 and a bit on #OpenData infrastructure 💽, I'm re-using the notion of Arrival from Katherine Trebeck and Jeremy Williams' book, the #Economics of Arrival. Might this help us researchers to bridge the Knowledge-Action Gap (see below) ?

Alzheimer's disrupts circadian rhythms of plaque-clearing brain cells

https://medicine.washu.edu/news/alzheimers-disrupts-circadian-rhythms-of-plaque-clearing-brain-cells/

#HackerNews #Circadian #Rhythms #BrainHealth #PlaqueClearing #Neuroscience

How are #circadian rhythms established during development? This study shows that maternal metabolic signals oscillate in the fetal #SCN before the endogenous #clock becomes functional, offering a plausible mechanism for maternal entrainment of the developing clock @PLOSBiology https://plos.io/3VD45fZ

Switching to permanent #standardtime would prevent about 300,000 cases of #stroke per year and result in 2.6 million fewer people with #obesity by better aligning #circadianrhythms with natural light.
"We found that staying in standard time or staying in #daylightsavingtime is definitely better than switching twice a year," senior researcher #JamieZeitzer said.
An out-of-sync #circadian cycle has been linked with many different poor #health outcomes, researchers said.
https://www.usnews.com/news/health-news/articles/2025-09-16/permanent-standard-time-could-cut-strokes-obesity-among-americans

Looking back 👋 warmly on a big #EBRS2025 conference in Lübeck on #circadian and other biological rhythms, with @kofanchen et al.
The city is charming, the surrounding river/canals/lakes relax the pace and the weather was on side 😄.

Now by rail on time 🚄, to start the journey home via Berlin, bon voyage to all the fellow delegates!

A short thread on #EBRS and #staygrounded 🧵

⏰ Body clock keeps 24-hour rhythm by distorting gene activity in the heat

... the linked paper has "Renormalization Group" in the title which is something I'm always for even if it is only a semigroup

https://medicalxpress.com/news/2025-07-body-clock-hour-rhythm-distorting.html

#biology #physics #biophysics #math #circadian #time #molbio #renormalizationgroup

Turned around and now travelling towards #Lubeck en route to EBRS2025, just a basin of Baltic and half Sweden to go 🛳️ 🚄 ⛴️

Over 50 trainees up for #circadian entrainment tutorial on Sunday, it seems 🤓 ⏰ #PRCparty

https://ebrs-online.org/index.php/events/ebrs2025/program.html

#staygrounded #flyingless #EBRS2025

Spatiotemporal analysis of >10 million #PrimaryCilia in 22 mouse #brain regions shows that #cilia have region-specific length & orientation patterns. #Circadian rhythms of cilia length suggest a role for cilia in the brain’s response to environmental changes @PLOSBiology https://plos.io/4lWnfbQ