#avacopan — Public Fediverse posts

And @[email protected] retracts ADVOCATE based on the FDA uncovering and 2 academic authors asking for article to be pulled. (Good on them!)

www.nejm.org/doi/10.1056/...

h/t @[email protected]

#Avacopan #vasculitis

RE: https://bsky.app/profile/did:plc:33h4q6nw674jdcwfxaq2m2nl/post/3mpcmhe7xh22o

Retraction: Jayne DRW et al. A...

And @[email protected] retracts ADVOCATE based on the FDA uncovering and 2 academic authors asking for article to be pulled. (Good on them!)

www.nejm.org/doi/10.1056/...

h/t @[email protected]

#Avacopan #vasculitis

RE: https://bsky.app/profile/did:plc:33h4q6nw674jdcwfxaq2m2nl/post/3mpcmhe7xh22o

Retraction: Jayne DRW et al. A...

CHMP recommends revoking marketing authorisation for TAVNEOS® (avacopan) in the European Union

Recommendation follows an Article 20 non-pharmacovigilance procedure Patients currently on TAVNEOS treatment should consult their treating physician  ST. GALLEN, Switzerland,…
#Europe #EU #authorisation #avacopan #CHMP #European #EuropeanUnion #for #in #marketing #recommends #revoking #TAVNEOS #the #Union
https://www.europesays.com/europe/80144/

CHMP recommends EU revocation of TAVNEOS

Recommendation follows an Article 20 non-pharmacovigilance procedure Patients currently on TAVNEOS treatment should consult their treating physician   ST. GALLEN,…
#Europe #EU #ANCA-associatedvasculitis #avacopan #CHMP #CSL #CSLLY #EMA #European #EuropeanCommission #TAVNEOS
https://www.europesays.com/europe/80132/

The #avacopan story in #ANCA vasculitis is messy. IMHO #Amgen should be forced to withdraw & do another registrational trial. If not, they should be forced to do a PASS under a REMS.
Finally was ava rolled out in Japan during a high #covid period -> VBS was due to virus+/-drug?

The #avacopan story in #ANCA vasculitis is messy. IMHO #Amgen should be forced to withdraw & do another registrational trial. If not, they should be forced to do a PASS under a REMS.
Finally was ava rolled out in Japan during a high #covid period -> VBS was due to virus+/-drug?

The #avacopan story in #ANCA vasculitis is messy. IMHO #Amgen should be forced to withdraw & do another registrational trial. If not, they should be forced to do a PASS under a REMS.
Finally was ava rolled out in Japan during a high #covid period -> VBS was due to virus+/-drug?

The #avacopan story in #ANCA vasculitis is messy. IMHO #Amgen should be forced to withdraw & do another registrational trial. If not, they should be forced to do a PASS under a REMS.
Finally was ava rolled out in Japan during a high #covid period -> VBS was due to virus+/-drug?

The #avacopan story in #ANCA vasculitis is messy. IMHO #Amgen should be forced to withdraw & do another registrational trial. If not, they should be forced to do a PASS under a REMS.
Finally was ava rolled out in Japan during a high #covid period -> VBS was due to virus+/-drug?

The #avacopan story in #ANCA vasculitis is messy. IMHO #Amgen should be forced to withdraw & do another registrational trial. If not, they should be forced to do a PASS under a REMS. Finally was ava rolled out in Japan during a high #covid period -> VBS was due to virus+/-drug?

The #avacopan story in #ANCA vasculitis is messy. IMHO #Amgen should be forced to withdraw & do another registrational trial. If not, they should be forced to do a PASS under a REMS. Finally was ava rolled out in Japan during a high #covid period -> VBS was due to virus+/-drug?

more h/t @[email protected]

www.fda.gov/drugs/drug-a...

accusations of selectively re-adjudicating with an intent to p-hack

#Avacopan #Tavneos

CDER proposes to withdraw appr...

more h/t @[email protected]

www.fda.gov/drugs/drug-a...

accusations of selectively re-adjudicating with an intent to p-hack

#Avacopan #Tavneos

CDER proposes to withdraw appr...

more h/t @[email protected] www.fda.gov/drugs/drug-a... accusations of selectively re-adjudicating with an intent to p-hack #Avacopan #Tavneos

CDER proposes to withdraw appr...

As @[email protected] sez (on the other site) given limited efficacy benefit anyways - #avacopan is now dead until proven otherwise Stop using it

Plus cases of Vanishing bile duct syndrome? Eg www.acpjournals.org/doi/10.7326/... And academic.oup.com/rheumatology... #NephSky #Vasculitis #Avacopan

Avacopan Causing Vanishing Bil...