#proteases — Public Fediverse posts

I am very happy that Michaela Prothiwa joined us today for a department visit and a lecture. She gave a very interesting lecture on "Chemical strategies to understand bacterial immune evasion".
https://link.springer.com/protocol/10.1007/978-1-0716-4502-4_11
#ChemBio #Chemistry #Bacteria #Proteases #Probes

Profiling endogenous #airway #proteases and antiproteases and measuring proteolytic #activation of #Influenza #HA using in vitro and ex vivo human airway surface #liquid samples, BioRxIV: https://www.biorxiv.org/content/10.1101/2024.06.14.599031v1?rss=1

This #assay presents a direct and efficient method of evaluating the proteolytic environment of human airway samples in assessment of therapeutic treatment, exposure, or underlying disease.

Hmm, interesting questions: when doing in-vitro protease digests with recombinant protease, do I exclude self-cleavages of the protease from the putative cleavages as it might be rather an artefact of the excess protease addition? #Proteases #Ntermini