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  1. 🚨 New hypothesis: One mechanism links schizophrenia, depression & PTSD: collapse of excitability margin (ΔVmargin) in ventral CA1.

    🎥 9-min explainer video: youtube.com/watch?v=DWbEN-F5ML

    🔗 Full preprint: osf.io/preprints/osf/e4cwb_v3

    #Neuroscience #Psychiatry #MentalHealth #Schizophrenia #Depression #PTSD #OpenScience #FediSci

  2. 🚨 New hypothesis: One mechanism links schizophrenia, depression & PTSD: collapse of excitability margin (ΔVmargin) in ventral CA1.
    Chronic stress (–11.3 mV), hot-spot recall (–3.2 mV) + risk factors (alleles, psychoactives, infections, diet, microplastics) converge. Once ΔVmargin <5 mV, engram valence → phenotype (fear→SZ, sadness→DEP, trauma→PTSD).
    📄 doi.org/10.31219/osf.io/e4cwb_
    #Neuroscience #Psychiatry #MentalHealth #Schizophrenia #Depression #PTSD #OpenScience #FediSci

  3. 🚨 New preprint: One mechanism links schizophrenia, depression & PTSD: collapse of excitability margin (ΔVmargin) in ventral CA1.
    Chronic stress (–11.3 mV), hot-spot recall (–3.2 mV) + risk factors (alleles, psychoactives, infections, diet, microplastics) converge. Once ΔVmargin <5 mV, engram valence → phenotype (fear→SZ, sadness→DEP, trauma→PTSD).
    📄 doi.org/10.31219/osf.io/e4cwb_
    #Neuroscience #Psychiatry #MentalHealth #Schizophrenia #Depression #PTSD #OpenScience #FediSci

  4. 🚨 New preprint: One mechanism links schizophrenia, depression & PTSD: collapse of excitability margin (ΔVmargin) in ventral CA1.
    Chronic stress (–11.3 mV), hot-spot recall (–3.2 mV) + risk factors (alleles, psychoactives, infections, diet, microplastics) converge. Once ΔVmargin <5 mV, engram valence → phenotype (fear→SZ, sadness→DEP, trauma→PTSD).

    📄 doi.org/10.31219/osf.io/e4cwb_

    #neuroscience #psychiatry #schizophrenia #depression #PTSD #brain #research #openScience #FediSci #MentalHealth

  5. New model links schizophrenia, depression & PTSD to one root cause: a dangerously narrowed excitability margin in hippocampal CA1.
    From stress & risk alleles to ELF fields & geomagnetic storms — one pathway, 3 phenotypes.
    🔗 doi.org/10.31219/osf.io/e4cwb_
    #Neuroscience #Psychiatry #MentalHealth #Schizophrenia #Depression #PTSD #OpenScience #FediSci

  6. New model links schizophrenia, depression & PTSD to one root cause: a dangerously narrowed excitability margin in hippocampal CA1.
    From stress & risk alleles to ELF fields & geomagnetic storms — one pathway, 3 phenotypes.
    🔗 doi.org/10.31219/osf.io/e4cwb_
    #Neuroscience #Psychiatry #MentalHealth #Schizophrenia #Depression #PTSD #OpenScience #FediSci

  7. New preprint/model: the Rosa-Margin Hypothesis. When the vCA1 safety buffer shrinks (<~5 mV), everyday network transients trigger involuntary replay of emotional engrams → SZ/MDD/PTSD trajectories.
    Falsifiable endpoints: MEG γ-burst ↓ ≥35%, HRV rMSSD +≥5 ms.
    Code+DOI:
    doi.org/10.31219/osf.io/e4cwb_
    #NeuroFediverse #Neuroscience #Hippocampus #Schizophrenia #Depression #PTSD #Oscillations #KCC2 #PVInterneurons #MEG #HRV #Preprint #OpenScience #FediSci #Science #Psychiatry #Brain