#zosurabalpin — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #zosurabalpin, aggregated by home.social.
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He also hinted at a new class of synthetic antibiotics that is in current development at Roche. Hopefully there are many more new antibiotics in the future. (7/7)
#Antibiotics #DrugDiscovery #DrugDevelopment #ChemBio #Chemistry #cryoEM #AMR #Resistance #Bacteria #SAR #Synthesis #Zosurabalpin
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If you are interested, make sure to come by! More information can be found here: https://www.universiteitleiden.nl/en/science/led3/led3-lectures
(2/2)#Antibiotics #DrugDiscovery #LPS #Bacteria #Zosurabalpin #Chemistry #ChemBio
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Experimental #antibiotic kills deadly #superbug, opens whole new class of #drugs
Relatively large molecule clogs a transport system, leading to lethal toxicity. In this case, the new #drug—dubbed #zosurabalpin—fights off the #GramNegative #bacterium carbapenem-resistant Acinetobacter baumannii, aka CRAB. Though it may sound obscure, it's an opportunistic, invasive #bacteria that often strikes hospitalized and critically ill patients, causing deadly #infections worldwide. https://arstechnica.com/science/2024/01/experimental-antibiotic-reveals-entirely-new-way-to-kill-drug-resistant-bacteria/ -
Experimental #antibiotic kills deadly #superbug, opens whole new class of #drugs
Relatively large molecule clogs a transport system, leading to lethal toxicity. In this case, the new #drug—dubbed #zosurabalpin—fights off the #GramNegative #bacterium carbapenem-resistant Acinetobacter baumannii, aka CRAB. Though it may sound obscure, it's an opportunistic, invasive #bacteria that often strikes hospitalized and critically ill patients, causing deadly #infections worldwide. https://arstechnica.com/science/2024/01/experimental-antibiotic-reveals-entirely-new-way-to-kill-drug-resistant-bacteria/ -
A new experimental antibiotic can handily knock off one of the world's most notoriously drug-resistant and deadly bacteria —in lab dishes and mice, at least.
It does so with a never-before-seen method, cracking open an entirely new class of drugs that could yield more desperately needed new therapies for fighting drug-resistant infections.
The new drug—dubbed #zosurabalpin—fights off the Gram-negative bacterium carbapenem-resistant Acinetobacter baumannii, aka #CRAB.
Though it may sound obscure, it's an opportunistic, invasive bacteria that often strikes hospitalized and critically ill patients, causing deadly infections worldwide.
It is extensively drug-resistant, with ongoing emergence of pan-resistant strains around the world—in other words, strains that are resistant to every current antibiotic available.
Mortality rates of invasive CRAB infections range from 40 to 60 percent.
In 2017, the World Health Organization listed it as a priority 1: critical pathogen, for which new antibiotics are needed most urgently.
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A new experimental antibiotic can handily knock off one of the world's most notoriously drug-resistant and deadly bacteria —in lab dishes and mice, at least.
It does so with a never-before-seen method, cracking open an entirely new class of drugs that could yield more desperately needed new therapies for fighting drug-resistant infections.
The new drug—dubbed #zosurabalpin—fights off the Gram-negative bacterium carbapenem-resistant Acinetobacter baumannii, aka #CRAB.
Though it may sound obscure, it's an opportunistic, invasive bacteria that often strikes hospitalized and critically ill patients, causing deadly infections worldwide.
It is extensively drug-resistant, with ongoing emergence of pan-resistant strains around the world—in other words, strains that are resistant to every current antibiotic available.
Mortality rates of invasive CRAB infections range from 40 to 60 percent.
In 2017, the World Health Organization listed it as a priority 1: critical pathogen, for which new antibiotics are needed most urgently.
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At last some good news:
Scientists hail new #antibiotic that can kill drug-resistant bacteria#Zosurabalpin has defeated strains of pneumonia and sepsis in mice, raising hopes for human trials
https://www.theguardian.com/science/2024/jan/03/scientists-new-class-antibiotic-kill-drug-resistant-bacteria?CMP=Share_AndroidApp_Other -
At last some good news:
Scientists hail new #antibiotic that can kill drug-resistant bacteria#Zosurabalpin has defeated strains of pneumonia and sepsis in mice, raising hopes for human trials
https://www.theguardian.com/science/2024/jan/03/scientists-new-class-antibiotic-kill-drug-resistant-bacteria?CMP=Share_AndroidApp_Other -
Scientists hail new antibiotic that can kill drug-resistant bacteria | Infectious diseases | The Guardian
https://www.theguardian.com/science/2024/jan/03/scientists-new-class-antibiotic-kill-drug-resistant-bacteria#Antibiotic
#DrugResistantBacteria
#NewAntibiotic
#Zosurabalpin
#Sepsis
#LPS
#Lipopolysaccharide
#GramNegativeBacteria -
Scientists hail new antibiotic that can kill drug-resistant bacteria | Infectious diseases | The Guardian
https://www.theguardian.com/science/2024/jan/03/scientists-new-class-antibiotic-kill-drug-resistant-bacteria#Antibiotic
#DrugResistantBacteria
#NewAntibiotic
#Zosurabalpin
#Sepsis
#LPS
#Lipopolysaccharide
#GramNegativeBacteria