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#zikavirus — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #zikavirus, aggregated by home.social.

  1. Circuito dos Cuidados: CNJ realiza encontro e lança documentário sobre ZikaPolítica de Cuidados e Circuito dos Cuidados: o CNJ realiza evento em 25 de maio no Auditório do CNJ, Brasília, com exibição do documentário Precisamo... #EventoseProgramações #CircuitodosCuidados #PolíticadeCuidados #Zikavírus
    direitohojenoticias.com.br/cir

  2. Zika virus secretly builds tiny tunnels to infect unborn babies. Penn State scientists reveal how—and why this discovery could stop future infections.

    #ZikaVirus #InfectiousDiseases #PublicHealth

    geekoo.news/tunnel-building-vi

  3. Zika virus secretly builds tiny tunnels to infect unborn babies. Penn State scientists reveal how—and why this discovery could stop future infections.

    #ZikaVirus #InfectiousDiseases #PublicHealth

    geekoo.news/tunnel-building-vi

  4. Zika virus secretly builds tiny tunnels to infect unborn babies. Penn State scientists reveal how—and why this discovery could stop future infections.

    #ZikaVirus #InfectiousDiseases #PublicHealth

    geekoo.news/tunnel-building-vi

  5. Protective threshold of a potent neutralizing #Zika virus monoclonal #antibody in rhesus #macaques

    Source: Journal of Virology, https://journals.asm.org/doi/full/10.1128/jvi.01429-24?af=R

    ABSTRACT
    Zika virus (ZIKV) is a mosquito-borne flavivirus that caused a global pandemic in 2016–2017 with continued ongoing transmission at low levels in several countries. In the absence of an approved ZIKV vaccine, neutralizing monoclonal antibodies (mAbs) provide an option for the prevention and treatment of ZIKV infection. Previous studies identified a potent neutralizing human mAb ZIKV-117 that reduced fetal infection and death in mice following ZIKV challenge. In this study, we report exquisite potency of ZIKV-117-LALA-YTE, which has been engineered to reduce Fc receptor binding and to extend half-life, in a titration study in rhesus macaques to protect against ZIKV challenge. We show complete protection at a dose of 0.016 mg/kg ZIKV-117-LALA-YTE, which resulted in median serum concentrations of 0.13 µg/mL. The high potency of this mAb supports its potential clinical development as a novel biotherapeutic intervention for ZIKV.

    ____

    #abstract #animalModels #monoclonalAntibodies #research #zikaVirus

  6. Protective threshold of a potent neutralizing #Zika virus monoclonal #antibody in rhesus #macaques

    Source: Journal of Virology, https://journals.asm.org/doi/full/10.1128/jvi.01429-24?af=R

    ABSTRACT
    Zika virus (ZIKV) is a mosquito-borne flavivirus that caused a global pandemic in 2016–2017 with continued ongoing transmission at low levels in several countries. In the absence of an approved ZIKV vaccine, neutralizing monoclonal antibodies (mAbs) provide an option for the prevention and treatment of ZIKV infection. Previous studies identified a potent neutralizing human mAb ZIKV-117 that reduced fetal infection and death in mice following ZIKV challenge. In this study, we report exquisite potency of ZIKV-117-LALA-YTE, which has been engineered to reduce Fc receptor binding and to extend half-life, in a titration study in rhesus macaques to protect against ZIKV challenge. We show complete protection at a dose of 0.016 mg/kg ZIKV-117-LALA-YTE, which resulted in median serum concentrations of 0.13 µg/mL. The high potency of this mAb supports its potential clinical development as a novel biotherapeutic intervention for ZIKV.

    ____

    #abstract #animalModels #monoclonalAntibodies #research #zikaVirus

  7. Protective threshold of a potent neutralizing #Zika virus monoclonal #antibody in rhesus #macaques

    Source: Journal of Virology, https://journals.asm.org/doi/full/10.1128/jvi.01429-24?af=R

    ABSTRACT
    Zika virus (ZIKV) is a mosquito-borne flavivirus that caused a global pandemic in 2016–2017 with continued ongoing transmission at low levels in several countries. In the absence of an approved ZIKV vaccine, neutralizing monoclonal antibodies (mAbs) provide an option for the prevention and treatment of ZIKV infection. Previous studies identified a potent neutralizing human mAb ZIKV-117 that reduced fetal infection and death in mice following ZIKV challenge. In this study, we report exquisite potency of ZIKV-117-LALA-YTE, which has been engineered to reduce Fc receptor binding and to extend half-life, in a titration study in rhesus macaques to protect against ZIKV challenge. We show complete protection at a dose of 0.016 mg/kg ZIKV-117-LALA-YTE, which resulted in median serum concentrations of 0.13 µg/mL. The high potency of this mAb supports its potential clinical development as a novel biotherapeutic intervention for ZIKV.

    ____

    #abstract #animalModels #monoclonalAntibodies #research #zikaVirus

  8. Protective threshold of a potent neutralizing #Zika virus monoclonal #antibody in rhesus #macaques

    Source: Journal of Virology, https://journals.asm.org/doi/full/10.1128/jvi.01429-24?af=R

    ABSTRACT
    Zika virus (ZIKV) is a mosquito-borne flavivirus that caused a global pandemic in 2016–2017 with continued ongoing transmission at low levels in several countries. In the absence of an approved ZIKV vaccine, neutralizing monoclonal antibodies (mAbs) provide an option for the prevention and treatment of ZIKV infection. Previous studies identified a potent neutralizing human mAb ZIKV-117 that reduced fetal infection and death in mice following ZIKV challenge. In this study, we report exquisite potency of ZIKV-117-LALA-YTE, which has been engineered to reduce Fc receptor binding and to extend half-life, in a titration study in rhesus macaques to protect against ZIKV challenge. We show complete protection at a dose of 0.016 mg/kg ZIKV-117-LALA-YTE, which resulted in median serum concentrations of 0.13 µg/mL. The high potency of this mAb supports its potential clinical development as a novel biotherapeutic intervention for ZIKV.

    ____

    #abstract #animalModels #monoclonalAntibodies #research #zikaVirus

  9. ⚡️ The Karnataka government has reported the detection of Zika virus in mosquitoes in Chikkaballapura district. They assure that the situation is well controlled, with intensified vector control measures, serum sampling of pregnant women, indoor space spraying, and information sessions. #ZikaVirus #PublicHealth riskmap.com/incidents/1946920/

  10. ⚡️ The Karnataka government has reported the detection of Zika virus in mosquitoes in Chikkaballapura district. They assure that the situation is well controlled, with intensified vector control measures, serum sampling of pregnant women, indoor space spraying, and information sessions. #ZikaVirus #PublicHealth riskmap.com/incidents/1946920/

  11. ⚡️ The Karnataka government has reported the detection of Zika virus in mosquitoes in Chikkaballapura district. They assure that the situation is well controlled, with intensified vector control measures, serum sampling of pregnant women, indoor space spraying, and information sessions. #ZikaVirus #PublicHealth riskmap.com/incidents/1946920/

  12. ⚡️ The Karnataka government has reported the detection of Zika virus in mosquitoes in Chikkaballapura district. They assure that the situation is well controlled, with intensified vector control measures, serum sampling of pregnant women, indoor space spraying, and information sessions. #ZikaVirus #PublicHealth riskmap.com/incidents/1946920/

  13. ⚡️ The Karnataka government has reported the detection of Zika virus in mosquitoes in Chikkaballapura district. They assure that the situation is well controlled, with intensified vector control measures, serum sampling of pregnant women, indoor space spraying, and information sessions. #ZikaVirus #PublicHealth riskmap.com/incidents/1946920/

  14. ⚡️ Zika virus outbreak in Thailand prompts warning by Department of Disease Control. Expectant mothers at high risk due to virus transmission to unborn children, causing birth defects. Public urged to eliminate mosquito breeding sites. Pregnant women advised to protect themselves from Aedes mosquito bites. #ZikaVirus #PublicHealthSafety riskmap.com/incidents/1884437/

  15. ⚡️ Zika virus outbreak in Thailand prompts warning by Department of Disease Control. Expectant mothers at high risk due to virus transmission to unborn children, causing birth defects. Public urged to eliminate mosquito breeding sites. Pregnant women advised to protect themselves from Aedes mosquito bites. #ZikaVirus #PublicHealthSafety riskmap.com/incidents/1884437/

  16. ⚡️ Zika virus outbreak in Thailand prompts warning by Department of Disease Control. Expectant mothers at high risk due to virus transmission to unborn children, causing birth defects. Public urged to eliminate mosquito breeding sites. Pregnant women advised to protect themselves from Aedes mosquito bites. #ZikaVirus #PublicHealthSafety riskmap.com/incidents/1884437/

  17. ⚡️ Zika virus outbreak in Thailand prompts warning by Department of Disease Control. Expectant mothers at high risk due to virus transmission to unborn children, causing birth defects. Public urged to eliminate mosquito breeding sites. Pregnant women advised to protect themselves from Aedes mosquito bites. #ZikaVirus #PublicHealthSafety riskmap.com/incidents/1884437/

  18. Zika cases surging in Thailand 🦟 🦟

    I wrote a review article on the role of mathematical modeling in understanding and predicting Zika virus transmission some years back.

    If it can aid in understanding the Zika virus transmission dynamics, please check it out:

    peerj.com/articles/4526/

    #Zikavirus #Zika #Virus #Thailand

  19. ⚡️ Zika virus infections are increasing in Thailand, particularly in regions with dengue fever. The government has issued a warning as the virus spreads rapidly across the country. While the mortality rate is low, the main concern is the potential risks to pregnant women, including miscarriage and birth defects. Zika is transmitted through mosquito bites. #ZikaVirus #Thailand #HealthRisk riskmap.com/incidents/1868537/

  20. ⚡️ Zika virus infections are increasing in Thailand, particularly in regions with dengue fever. The government has issued a warning as the virus spreads rapidly across the country. While the mortality rate is low, the main concern is the potential risks to pregnant women, including miscarriage and birth defects. Zika is transmitted through mosquito bites. #ZikaVirus #Thailand #HealthRisk riskmap.com/incidents/1868537/

  21. ⚡️ Zika virus infections are increasing in Thailand, particularly in regions with dengue fever. The government has issued a warning as the virus spreads rapidly across the country. While the mortality rate is low, the main concern is the potential risks to pregnant women, including miscarriage and birth defects. Zika is transmitted through mosquito bites. #ZikaVirus #Thailand #HealthRisk riskmap.com/incidents/1868537/

  22. Das #Zikavirus könnte bei der Therapie von Prostakarzinomen helfen, berichten Forscher. Was es damit auf sich hat, lest ihr hier. docc.hk/gzbut3

  23. Das #Zikavirus könnte bei der Therapie von Prostakarzinomen helfen, berichten Forscher. Was es damit auf sich hat, lest ihr hier. docc.hk/gzbut3

  24. Das #Zikavirus könnte bei der Therapie von Prostakarzinomen helfen, berichten Forscher. Was es damit auf sich hat, lest ihr hier. docc.hk/gzbut3

  25. New Zika virus lineages show increased fitness
    #ZikaVirus
    #Zika
    #PLOS
    #NeglectedTropicalDiseases
    #PhenitypicAdaptation
    #Mosquito
    #Mosquitos
    #Mozzies
    #Clades
    #Mutations
    #ZikaEpidemic news-medical.net/news/20230209
    >The current study, published in the journal PLOS Neglected Tropical Diseases, aimed to explore the possible phenotypic adaptation of the Zika virus to increase its transmissibility and virulence in the Americas.

  26. New Zika virus lineages show increased fitness
    #ZikaVirus
    #Zika
    #PLOS
    #NeglectedTropicalDiseases
    #PhenitypicAdaptation
    #Mosquito
    #Mosquitos
    #Mozzies
    #Clades
    #Mutations
    #ZikaEpidemic news-medical.net/news/20230209
    >The current study, published in the journal PLOS Neglected Tropical Diseases, aimed to explore the possible phenotypic adaptation of the Zika virus to increase its transmissibility and virulence in the Americas.

  27. New Zika virus lineages show increased fitness
    #ZikaVirus
    #Zika
    #PLOS
    #NeglectedTropicalDiseases
    #PhenitypicAdaptation
    #Mosquito
    #Mosquitos
    #Mozzies
    #Clades
    #Mutations
    #ZikaEpidemic news-medical.net/news/20230209
    >The current study, published in the journal PLOS Neglected Tropical Diseases, aimed to explore the possible phenotypic adaptation of the Zika virus to increase its transmissibility and virulence in the Americas.

  28. New Zika virus lineages show increased fitness
    #ZikaVirus
    #Zika
    #PLOS
    #NeglectedTropicalDiseases
    #PhenitypicAdaptation
    #Mosquito
    #Mosquitos
    #Mozzies
    #Clades
    #Mutations
    #ZikaEpidemic news-medical.net/news/20230209
    >The current study, published in the journal PLOS Neglected Tropical Diseases, aimed to explore the possible phenotypic adaptation of the Zika virus to increase its transmissibility and virulence in the Americas.