#xraycrystallography — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #xraycrystallography, aggregated by home.social.
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The first structure of a cold-active arginase reveals a modest reduction in structural rigidity associated with cold adaptation @BirkbeckUoL @ActaCrystF @IUCr #ColdActiveEnzymes #Arginases #XRayCrystallography https://doi.org/10.1107/S2053230X26003092
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The first structure of a cold-active arginase reveals a modest reduction in structural rigidity associated with cold adaptation @BirkbeckUoL @ActaCrystF @IUCr #ColdActiveEnzymes #Arginases #XRayCrystallography https://doi.org/10.1107/S2053230X26003092
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The first structure of a cold-active arginase reveals a modest reduction in structural rigidity associated with cold adaptation @BirkbeckUoL @ActaCrystF @IUCr #ColdActiveEnzymes #Arginases #XRayCrystallography https://doi.org/10.1107/S2053230X26003092
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Modifying the bacterial strain led to cleaner bacterial expression of a synthetic BRIL antibody that facilitates protein structure determination via both crystallography and cryo-EM #CryoEM #XRayCrystallography #BRIL https://doi.org/10.1107/S2053230X26001548
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Modifying the bacterial strain led to cleaner bacterial expression of a synthetic BRIL antibody that facilitates protein structure determination via both crystallography and cryo-EM #CryoEM #XRayCrystallography #BRIL https://doi.org/10.1107/S2053230X26001548
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Modifying the bacterial strain led to cleaner bacterial expression of a synthetic BRIL antibody that facilitates protein structure determination via both crystallography and cryo-EM #CryoEM #XRayCrystallography #BRIL https://doi.org/10.1107/S2053230X26001548
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High-resolution structures of α-bCA2 with sulfonamide derivatives provides experimentally supported information defining their binding mode and supporting inhibitor optimization #CarbonicAnhydraseII #SulfonamideInhibitors #XRayCrystallography https://doi.org/10.1107/S2053230X26002128
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High-resolution structures of α-bCA2 with sulfonamide derivatives provides experimentally supported information defining their binding mode and supporting inhibitor optimization #CarbonicAnhydraseII #SulfonamideInhibitors #XRayCrystallography https://doi.org/10.1107/S2053230X26002128
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High-resolution structures of α-bCA2 with sulfonamide derivatives provides experimentally supported information defining their binding mode and supporting inhibitor optimization #CarbonicAnhydraseII #SulfonamideInhibitors #XRayCrystallography https://doi.org/10.1107/S2053230X26002128
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#RosalindFranklin: 37 years of life. 16 years of science.
Beyond DNA. Beyond the lost #Nobel Prize or two(?)
Her #XrayCrystallography ignited:
• Carbon chemistry & fuel efficiency
• Seeds of #MolecularBiology and genomics
• Foundations of structural #virologyFull story here:
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#RosalindFranklin: 37 years of life. 16 years of science.
Beyond DNA. Beyond the lost #Nobel Prize or two(?)
Her #XrayCrystallography ignited:
• Carbon chemistry & fuel efficiency
• Seeds of #MolecularBiology and genomics
• Foundations of structural #virologyFull story here:
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#RosalindFranklin: 37 years of life. 16 years of science.
Beyond DNA. Beyond the lost #Nobel Prize or two(?)
Her #XrayCrystallography ignited:
• Carbon chemistry & fuel efficiency
• Seeds of #MolecularBiology and genomics
• Foundations of structural #virologyFull story here:
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#RosalindFranklin: 37 years of life. 16 years of science.
Beyond DNA. Beyond the lost #Nobel Prize or two(?)
Her #XrayCrystallography ignited:
• Carbon chemistry & fuel efficiency
• Seeds of #MolecularBiology and genomics
• Foundations of structural #virologyFull story here:
-
#RosalindFranklin: 37 years of life. 16 years of science.
Beyond DNA. Beyond the lost #Nobel Prize or two(?)
Her #XrayCrystallography ignited:
• Carbon chemistry & fuel efficiency
• Seeds of #MolecularBiology and genomics
• Foundations of structural #virologyFull story here:
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#RosalindFranklin Life of 37 years. 16 in science. 2 unraveling DNA.
1950s #XRayCrystallography No easy feat.
DNA story, #NobelPrize clashes, gender barriers. #ScienceHistory
Other XRC pioneer women. #WomenInSTEM
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#RosalindFranklin Life of 37 years. 16 in science. 2 unraveling DNA.
1950s #XRayCrystallography No easy feat.
DNA story, #NobelPrize clashes, gender barriers. #ScienceHistory
Other XRC pioneer women. #WomenInSTEM
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#RosalindFranklin Life of 37 years. 16 in science. 2 unraveling DNA.
1950s #XRayCrystallography No easy feat.
DNA story, #NobelPrize clashes, gender barriers. #ScienceHistory
Other XRC pioneer women. #WomenInSTEM
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#RosalindFranklin Life of 37 years. 16 in science. 2 unraveling DNA.
1950s #XRayCrystallography No easy feat.
DNA story, #NobelPrize clashes, gender barriers. #ScienceHistory
Other XRC pioneer women. #WomenInSTEM
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#RosalindFranklin Life of 37 years. 16 in science. 2 unraveling DNA.
1950s #XRayCrystallography No easy feat.
DNA story, #NobelPrize clashes, gender barriers. #ScienceHistory
Other XRC pioneer women. #WomenInSTEM
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How do enzymes, nature's highly efficient catalysts, achieve almost perfect precision and efficiency?
This is the research question to be addressed by newly funded project in chemistry: “NEXT - Quantum Biology”. The funding will strengthen #interdisciplinary teams and bridge #StructureBiology and #QuantumPhysics.
Congratulations to researchers at our Uni, MPI-NAT in Göttingen, and Hamburg Uni: www.uni-goettingen.de/en/3240.html?id=8028. With thanks to the Volkswagen Foundation.
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How do enzymes, nature's highly efficient catalysts, achieve almost perfect precision and efficiency?
This is the research question to be addressed by newly funded project in chemistry: “NEXT - Quantum Biology”. The funding will strengthen #interdisciplinary teams and bridge #StructureBiology and #QuantumPhysics.
Congratulations to researchers at our Uni, MPI-NAT in Göttingen, and Hamburg Uni: www.uni-goettingen.de/en/3240.html?id=8028. With thanks to the Volkswagen Foundation.
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How do enzymes, nature's highly efficient catalysts, achieve almost perfect precision and efficiency?
This is the research question to be addressed by newly funded project in chemistry: “NEXT - Quantum Biology”. The funding will strengthen #interdisciplinary teams and bridge #StructureBiology and #QuantumPhysics.
Congratulations to researchers at our Uni, MPI-NAT in Göttingen, and Hamburg Uni: www.uni-goettingen.de/en/3240.html?id=8028. With thanks to the Volkswagen Foundation.
-
How do enzymes, nature's highly efficient catalysts, achieve almost perfect precision and efficiency?
This is the research question to be addressed by newly funded project in chemistry: “NEXT - Quantum Biology”. The funding will strengthen #interdisciplinary teams and bridge #StructureBiology and #QuantumPhysics.
Congratulations to researchers at our Uni, MPI-NAT in Göttingen, and Hamburg Uni: www.uni-goettingen.de/en/3240.html?id=8028. With thanks to the Volkswagen Foundation.
-
How do enzymes, nature's highly efficient catalysts, achieve almost perfect precision and efficiency?
This is the research question to be addressed by newly funded project in chemistry: “NEXT - Quantum Biology”. The funding will strengthen #interdisciplinary teams and bridge #StructureBiology and #QuantumPhysics.
Congratulations to researchers at our Uni, MPI-NAT in Göttingen, and Hamburg Uni: www.uni-goettingen.de/en/3240.html?id=8028. With thanks to the Volkswagen Foundation.
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Features of sample preparation that should be considered prior to biomolecular crystallization experiments are reviewed, as described in the SAMPREP workshop during the 73rd Annual ACA Meeting #Crystallization #XRayCrystallography #StructuralBiology https://doi.org/10.1107/S2053230X25004650
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Features of sample preparation that should be considered prior to biomolecular crystallization experiments are reviewed, as described in the SAMPREP workshop during the 73rd Annual ACA Meeting #Crystallization #XRayCrystallography #StructuralBiology https://doi.org/10.1107/S2053230X25004650
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Features of sample preparation that should be considered prior to biomolecular crystallization experiments are reviewed, as described in the SAMPREP workshop during the 73rd Annual ACA Meeting #Crystallization #XRayCrystallography #StructuralBiology https://doi.org/10.1107/S2053230X25004650
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The structure of the C1 domain of the surface-layer protein SlpM from L. brevis provides new insights into the architecture and evolutionary adaptability of SLPs in Lactobacillus species #XRayCrystallography #SurfaceLayerProtein #SlpM https://doi.org/10.1107/S2053230X25004194
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The structure of the C1 domain of the surface-layer protein SlpM from L. brevis provides new insights into the architecture and evolutionary adaptability of SLPs in Lactobacillus species #XRayCrystallography #SurfaceLayerProtein #SlpM https://doi.org/10.1107/S2053230X25004194
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The structure of the C1 domain of the surface-layer protein SlpM from L. brevis provides new insights into the architecture and evolutionary adaptability of SLPs in Lactobacillus species #XRayCrystallography #SurfaceLayerProtein #SlpM https://doi.org/10.1107/S2053230X25004194
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Postdoctoral Scholar-Structural Biology in Protein Dynamics
Icahn School of Medicine at Mount Sinai
Join our lab as a #StructuralBiology #Postdoc to study proteins in #Alzheimers & #Cancer using #CryoEM & #XrayCrystallography at Mount Sinai!
See the full job description on jobRxiv: https://jobrxiv.org/job/icahn-school-of-medicine-at-mount-sinai...
https://jobrxiv.org/job/icahn-school-of-medicine-at-mount-sinai-27778-postdoctoral-scholar-structural-biology-in-protein-dynamics-2/?feed_id=89569 -
Postdoctoral Scholar-Structural Biology in Protein Dynamics
Icahn School of Medicine at Mount Sinai
Join our lab as a #StructuralBiology #Postdoc to study proteins in #Alzheimers & #Cancer using #CryoEM & #XrayCrystallography at Mount Sinai!
See the full job description on jobRxiv: https://jobrxiv.org/job/icahn-school-of-medicine-at-mount-sinai...
https://jobrxiv.org/job/icahn-school-of-medicine-at-mount-sinai-27778-postdoctoral-scholar-structural-biology-in-protein-dynamics-2/?feed_id=89569 -
Postdoctoral Scholar-Structural Biology in Protein Dynamics
Icahn School of Medicine at Mount Sinai
Join our lab as a #StructuralBiology #Postdoc to study proteins in #Alzheimers & #Cancer using #CryoEM & #XrayCrystallography at Mount Sinai!
See the full job description on jobRxiv: https://jobrxiv.org/job/icahn-school-of-medicine-at-mount-sinai...
https://jobrxiv.org/job/icahn-school-of-medicine-at-mount-sinai-27778-postdoctoral-scholar-structural-biology-in-protein-dynamics-2/?feed_id=89569 -
Postdoctoral Scholar-Structural Biology in Protein Dynamics
Icahn School of Medicine at Mount Sinai
Join our lab as a #StructuralBiology #Postdoc to study proteins in #Alzheimers & #Cancer using #CryoEM & #XrayCrystallography at Mount Sinai!
See the full job description on jobRxiv: https://jobrxiv.org/job/icahn-school-of-medicine-at-mount-sinai...
https://jobrxiv.org/job/icahn-school-of-medicine-at-mount-sinai-27778-postdoctoral-scholar-structural-biology-in-protein-dynamics-2/?feed_id=89569 -
Postdoctoral Scholar-Structural Biology in Protein Dynamics
Icahn School of Medicine at Mount Sinai
Join our lab as a #StructuralBiology #Postdoc to study proteins in #Alzheimers & #Cancer using #CryoEM & #XrayCrystallography at Mount Sinai!
See the full job description on jobRxiv: https://jobrxiv.org/job/icahn-school-of-medicine-at-mount-sinai...
https://jobrxiv.org/job/icahn-school-of-medicine-at-mount-sinai-27778-postdoctoral-scholar-structural-biology-in-protein-dynamics-2/?feed_id=89569 -
Postdoctoral Scholar-Structural Biology in Protein Dynamics
Icahn School of Medicine at Mount Sinai
Join our lab as a #StructuralBiology #Postdoc to study proteins in #Alzheimers & #Cancer using #CryoEM & #XrayCrystallography at Mount Sinai!
See the full job description on jobRxiv: https://jobrxiv.org/job/icahn-school-of-medicine-at-mount-sinai...
https://jobrxiv.org/job/icahn-school-of-medicine-at-mount-sinai-27778-postdoctoral-scholar-structural-biology-in-protein-dynamics-2/?feed_id=89072 -
Postdoctoral Scholar-Structural Biology in Protein Dynamics
Icahn School of Medicine at Mount Sinai
Join our lab as a #StructuralBiology #Postdoc to study proteins in #Alzheimers & #Cancer using #CryoEM & #XrayCrystallography at Mount Sinai!
See the full job description on jobRxiv: https://jobrxiv.org/job/icahn-school-of-medicine-at-mount-sinai...
https://jobrxiv.org/job/icahn-school-of-medicine-at-mount-sinai-27778-postdoctoral-scholar-structural-biology-in-protein-dynamics-2/?feed_id=89072 -
Postdoctoral Scholar-Structural Biology in Protein Dynamics
Icahn School of Medicine at Mount Sinai
Join our lab as a #StructuralBiology #Postdoc to study proteins in #Alzheimers & #Cancer using #CryoEM & #XrayCrystallography at Mount Sinai!
See the full job description on jobRxiv: https://jobrxiv.org/job/icahn-school-of-medicine-at-mount-sinai...
https://jobrxiv.org/job/icahn-school-of-medicine-at-mount-sinai-27778-postdoctoral-scholar-structural-biology-in-protein-dynamics-2/?feed_id=89072 -
Postdoctoral Scholar-Structural Biology in Protein Dynamics
Icahn School of Medicine at Mount Sinai
Join our lab as a #StructuralBiology #Postdoc to study proteins in #Alzheimers & #Cancer using #CryoEM & #XrayCrystallography at Mount Sinai!
See the full job description on jobRxiv: https://jobrxiv.org/job/icahn-school-of-medicine-at-mount-sinai...
https://jobrxiv.org/job/icahn-school-of-medicine-at-mount-sinai-27778-postdoctoral-scholar-structural-biology-in-protein-dynamics-2/?feed_id=89072 -
Postdoctoral Scholar-Structural Biology in Protein Dynamics
Icahn School of Medicine at Mount Sinai
Join our lab as a #StructuralBiology #Postdoc to study proteins in #Alzheimers & #Cancer using #CryoEM & #XrayCrystallography at Mount Sinai!
See the full job description on jobRxiv: https://jobrxiv.org/job/icahn-school-of-medicine-at-mount-sinai...
https://jobrxiv.org/job/icahn-school-of-medicine-at-mount-sinai-27778-postdoctoral-scholar-structural-biology-in-protein-dynamics-2/?feed_id=89072 -
Unlike other serpins, human serpin B9 shows significant structural deviations around helix D, with a larger surface cavity, which could serve as a promising target for small-molecule inhibitors #Serpins #XRayCrystallography #Crystallization https://t.co/ilB7Aa3Krg
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Unlike other serpins, human serpin B9 shows significant structural deviations around helix D, with a larger surface cavity, which could serve as a promising target for small-molecule inhibitors #Serpins #XRayCrystallography #Crystallization https://t.co/ilB7Aa3Krg
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Unlike other serpins, human serpin B9 shows significant structural deviations around helix D, with a larger surface cavity, which could serve as a promising target for small-molecule inhibitors #Serpins #XRayCrystallography #Crystallization https://t.co/ilB7Aa3Krg
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This topical review focuses on 13 X-ray crystal structures and five electron cryo-microscopy structures of glucose-6-phosphate dehydrogenase in the PDB #Glucose6PhosphateDehydrogenase #XRayCrystallography #ElectronCryoMicroscopy https://doi.org/10.1107/S2053230X24008112
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This topical review focuses on 13 X-ray crystal structures and five electron cryo-microscopy structures of glucose-6-phosphate dehydrogenase in the PDB #Glucose6PhosphateDehydrogenase #XRayCrystallography #ElectronCryoMicroscopy https://doi.org/10.1107/S2053230X24008112
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This topical review focuses on 13 X-ray crystal structures and five electron cryo-microscopy structures of glucose-6-phosphate dehydrogenase in the PDB #Glucose6PhosphateDehydrogenase #XRayCrystallography #ElectronCryoMicroscopy https://doi.org/10.1107/S2053230X24008112
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The structure of the Rib domain from Limosilactobacillus reuteri is compared with previously published models and is found to exhibit extraordinary thermal stability #XRayCrystallography #RibDomain #ImmunoglobulinLikeFold https://t.co/y4cUSd1bHR
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The structure of the Rib domain from Limosilactobacillus reuteri is compared with previously published models and is found to exhibit extraordinary thermal stability #XRayCrystallography #RibDomain #ImmunoglobulinLikeFold https://t.co/y4cUSd1bHR
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The structure of the Rib domain from Limosilactobacillus reuteri is compared with previously published models and is found to exhibit extraordinary thermal stability #XRayCrystallography #RibDomain #ImmunoglobulinLikeFold https://t.co/y4cUSd1bHR
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A true apo PTPN2 crystal structure with an unbound active site allowed the active site to be observed in a native apo state for the first time and inhibitor complexes were obtained by soaking experiments #PTPN2 #Phosphatases #XRayCrystallography https://doi.org/10.1107/S2053230X24007866
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A true apo PTPN2 crystal structure with an unbound active site allowed the active site to be observed in a native apo state for the first time and inhibitor complexes were obtained by soaking experiments #PTPN2 #Phosphatases #XRayCrystallography https://doi.org/10.1107/S2053230X24007866
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A true apo PTPN2 crystal structure with an unbound active site allowed the active site to be observed in a native apo state for the first time and inhibitor complexes were obtained by soaking experiments #PTPN2 #Phosphatases #XRayCrystallography https://doi.org/10.1107/S2053230X24007866
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This long Rib domain demonstrates a highly conserved structure and also highlights an evolutionary convergence in structural architecture with other modular domains in cell-adhesion molecules. #BacterialAdhesins #RibDomains #XRayCrystallography https://t.co/NxObHw6qHN
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This long Rib domain demonstrates a highly conserved structure and also highlights an evolutionary convergence in structural architecture with other modular domains in cell-adhesion molecules. #BacterialAdhesins #RibDomains #XRayCrystallography https://t.co/NxObHw6qHN
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This long Rib domain demonstrates a highly conserved structure and also highlights an evolutionary convergence in structural architecture with other modular domains in cell-adhesion molecules. #BacterialAdhesins #RibDomains #XRayCrystallography https://t.co/NxObHw6qHN
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SBGrid's eLife paper received a new citation in August from SBGrid member Stephen Blacklow Harvard Medical School in Cell: Structural basis for membrane-proximal proteolysis of substrates by ADAM10.
<ALT= Structural Basis for Regulated Proteolysis by the α-Secretase ADAM10>
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SBGrid's eLife paper received a new citation in August from SBGrid member Stephen Blacklow Harvard Medical School in Cell: Structural basis for membrane-proximal proteolysis of substrates by ADAM10.
<ALT= Structural Basis for Regulated Proteolysis by the α-Secretase ADAM10>
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The first serial synchrotron crystallography structure of apo PTP1B indicates a degree of allosteric decoupling that adds nuance to the previously reported paradigm of allostery in this protein #XRayCrystallography #Phosphatase #Allostery #openaccess https://doi.org/10.1107/S2053230X22011645
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The first serial synchrotron crystallography structure of apo PTP1B indicates a degree of allosteric decoupling that adds nuance to the previously reported paradigm of allostery in this protein #XRayCrystallography #Phosphatase #Allostery #openaccess https://doi.org/10.1107/S2053230X22011645
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Hi @DNPFred
In grad school I worked on heme proteins using #paramagnetic #NMR and #NRVS. Then I shifted to #XRayCrystallography, using #EPR #UVVis and #EDX on #crystals when a postdoc. My research group works on #NonHemeIron #enzymes, & #heme, #copper & #manganese #metalloproteins. Really interested in combining #spectroscopy on #protein #crystals to examine #structure #function relationships.